| Full name: apolipoprotein L5 | Alias Symbol: APOLV | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 80831 | HGNC ID: HGNC:14869 | Ensembl Gene: ENSG00000128313 | OMIM ID: 607255 |
| Drug and gene relationship at DGIdb | |||
Expression of APOL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APOL5 | 80831 | 220478_at | 0.0175 | 0.9592 | |
| GSE20347 | APOL5 | 80831 | 220478_at | -0.1576 | 0.0337 | |
| GSE23400 | APOL5 | 80831 | 220478_at | -0.2165 | 0.0000 | |
| GSE26886 | APOL5 | 80831 | 220478_at | 0.1468 | 0.2780 | |
| GSE29001 | APOL5 | 80831 | 220478_at | -0.2882 | 0.0225 | |
| GSE38129 | APOL5 | 80831 | 220478_at | -0.2054 | 0.0314 | |
| GSE45670 | APOL5 | 80831 | 220478_at | 0.0023 | 0.9882 | |
| GSE53622 | APOL5 | 80831 | 62149 | -0.1025 | 0.3298 | |
| GSE53624 | APOL5 | 80831 | 62149 | -0.3505 | 0.0000 | |
| GSE63941 | APOL5 | 80831 | 220478_at | 0.1040 | 0.4845 | |
| GSE77861 | APOL5 | 80831 | 220478_at | -0.3056 | 0.0117 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by APOL5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APOL5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APOL5 | 80831 | 4 | 6 | 20 | |
| GSE20123 | APOL5 | 80831 | 4 | 5 | 21 | |
| GSE43470 | APOL5 | 80831 | 4 | 7 | 32 | |
| GSE46452 | APOL5 | 80831 | 31 | 1 | 27 | |
| GSE47630 | APOL5 | 80831 | 8 | 5 | 27 | |
| GSE54993 | APOL5 | 80831 | 3 | 6 | 61 | |
| GSE54994 | APOL5 | 80831 | 9 | 9 | 35 | |
| GSE60625 | APOL5 | 80831 | 5 | 0 | 6 | |
| GSE74703 | APOL5 | 80831 | 4 | 5 | 27 | |
| GSE74704 | APOL5 | 80831 | 1 | 2 | 17 | |
| TCGA | APOL5 | 80831 | 27 | 15 | 54 |
Total number of gains: 100; Total number of losses: 61; Total Number of normals: 327.
Somatic mutations of APOL5:
Generating mutation plots.
Highly correlated genes for APOL5:
Showing top 20/867 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APOL5 | KLF15 | 0.718837 | 3 | 0 | 3 |
| APOL5 | FSTL4 | 0.716635 | 4 | 0 | 4 |
| APOL5 | ZMAT4 | 0.700637 | 3 | 0 | 3 |
| APOL5 | OR2S2 | 0.698578 | 3 | 0 | 3 |
| APOL5 | AMELY | 0.696531 | 3 | 0 | 3 |
| APOL5 | SLC6A5 | 0.694391 | 3 | 0 | 3 |
| APOL5 | GRPR | 0.688477 | 3 | 0 | 3 |
| APOL5 | NOS1 | 0.686386 | 5 | 0 | 4 |
| APOL5 | KLK3 | 0.686067 | 3 | 0 | 3 |
| APOL5 | DISC1 | 0.677448 | 4 | 0 | 4 |
| APOL5 | RBP4 | 0.672503 | 3 | 0 | 3 |
| APOL5 | GALNTL5 | 0.672255 | 3 | 0 | 3 |
| APOL5 | IL12A | 0.672097 | 3 | 0 | 3 |
| APOL5 | HOXC5 | 0.667064 | 3 | 0 | 3 |
| APOL5 | PIK3R5 | 0.666973 | 5 | 0 | 5 |
| APOL5 | KIF25 | 0.665639 | 4 | 0 | 3 |
| APOL5 | DNAI1 | 0.664638 | 3 | 0 | 3 |
| APOL5 | GALR3 | 0.659774 | 6 | 0 | 6 |
| APOL5 | IL17RC | 0.658053 | 6 | 0 | 4 |
| APOL5 | ALDH3B1 | 0.657892 | 5 | 0 | 4 |
For details and further investigation, click here
