| Full name: PWWP domain containing 2A | Alias Symbol: KIAA1935 | ||
| Type: protein-coding gene | Cytoband: 5q33.3 | ||
| Entrez ID: 114825 | HGNC ID: HGNC:29406 | Ensembl Gene: ENSG00000170234 | OMIM ID: 617823 |
| Drug and gene relationship at DGIdb | |||
Expression of PWWP2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PWWP2A | 114825 | 228336_at | 0.0676 | 0.8219 | |
| GSE20347 | PWWP2A | 114825 | 217533_x_at | -0.0184 | 0.7677 | |
| GSE23400 | PWWP2A | 114825 | 217533_x_at | -0.0311 | 0.4380 | |
| GSE26886 | PWWP2A | 114825 | 226720_at | -0.0345 | 0.9171 | |
| GSE29001 | PWWP2A | 114825 | 217533_x_at | -0.1087 | 0.5531 | |
| GSE38129 | PWWP2A | 114825 | 217533_x_at | -0.0803 | 0.0804 | |
| GSE45670 | PWWP2A | 114825 | 226720_at | 0.2559 | 0.0913 | |
| GSE53622 | PWWP2A | 114825 | 31352 | -0.2845 | 0.0014 | |
| GSE53624 | PWWP2A | 114825 | 31352 | -0.1713 | 0.0286 | |
| GSE63941 | PWWP2A | 114825 | 228336_at | -0.1396 | 0.7322 | |
| GSE77861 | PWWP2A | 114825 | 226720_at | -0.0124 | 0.9649 | |
| GSE97050 | PWWP2A | 114825 | A_23_P398770 | 0.2667 | 0.2585 | |
| SRP007169 | PWWP2A | 114825 | RNAseq | -0.6161 | 0.0665 | |
| SRP008496 | PWWP2A | 114825 | RNAseq | -0.6699 | 0.0008 | |
| SRP064894 | PWWP2A | 114825 | RNAseq | 0.0240 | 0.9024 | |
| SRP133303 | PWWP2A | 114825 | RNAseq | 0.0758 | 0.3558 | |
| SRP159526 | PWWP2A | 114825 | RNAseq | -0.3784 | 0.2168 | |
| SRP193095 | PWWP2A | 114825 | RNAseq | -0.2156 | 0.0102 | |
| SRP219564 | PWWP2A | 114825 | RNAseq | -0.0219 | 0.9454 | |
| TCGA | PWWP2A | 114825 | RNAseq | -0.2203 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PWWP2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PWWP2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PWWP2A | 114825 | 0 | 11 | 19 | |
| GSE20123 | PWWP2A | 114825 | 0 | 11 | 19 | |
| GSE43470 | PWWP2A | 114825 | 2 | 10 | 31 | |
| GSE46452 | PWWP2A | 114825 | 0 | 27 | 32 | |
| GSE47630 | PWWP2A | 114825 | 0 | 20 | 20 | |
| GSE54993 | PWWP2A | 114825 | 9 | 2 | 59 | |
| GSE54994 | PWWP2A | 114825 | 1 | 16 | 36 | |
| GSE60625 | PWWP2A | 114825 | 0 | 0 | 11 | |
| GSE74703 | PWWP2A | 114825 | 2 | 8 | 26 | |
| GSE74704 | PWWP2A | 114825 | 0 | 6 | 14 | |
| TCGA | PWWP2A | 114825 | 4 | 37 | 55 |
Total number of gains: 18; Total number of losses: 148; Total Number of normals: 322.
Somatic mutations of PWWP2A:
Generating mutation plots.
Highly correlated genes for PWWP2A:
Showing top 20/276 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PWWP2A | USP37 | 0.783679 | 3 | 0 | 3 |
| PWWP2A | NIN | 0.77714 | 3 | 0 | 3 |
| PWWP2A | CDC14A | 0.7769 | 3 | 0 | 3 |
| PWWP2A | ZNF771 | 0.773123 | 3 | 0 | 3 |
| PWWP2A | C2CD2 | 0.769703 | 3 | 0 | 3 |
| PWWP2A | GMCL1 | 0.766979 | 3 | 0 | 3 |
| PWWP2A | TEX261 | 0.749963 | 3 | 0 | 3 |
| PWWP2A | THRAP3 | 0.749531 | 3 | 0 | 3 |
| PWWP2A | CNTF | 0.734943 | 4 | 0 | 3 |
| PWWP2A | KLHL24 | 0.733423 | 3 | 0 | 3 |
| PWWP2A | TAF1C | 0.730855 | 3 | 0 | 3 |
| PWWP2A | ATG4C | 0.730758 | 4 | 0 | 3 |
| PWWP2A | CTDSP1 | 0.728833 | 3 | 0 | 3 |
| PWWP2A | RPUSD4 | 0.727853 | 3 | 0 | 3 |
| PWWP2A | ZBTB33 | 0.723262 | 3 | 0 | 3 |
| PWWP2A | ERCC4 | 0.723106 | 3 | 0 | 3 |
| PWWP2A | DOCK5 | 0.72253 | 3 | 0 | 3 |
| PWWP2A | PRDM10 | 0.721985 | 3 | 0 | 3 |
| PWWP2A | CDC42EP1 | 0.71836 | 3 | 0 | 3 |
| PWWP2A | BOD1 | 0.717688 | 3 | 0 | 3 |
For details and further investigation, click here
