| Full name: phosphoglucomutase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p31.3 | ||
| Entrez ID: 5236 | HGNC ID: HGNC:8905 | Ensembl Gene: ENSG00000079739 | OMIM ID: 171900 |
| Drug and gene relationship at DGIdb | |||
Expression of PGM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PGM1 | 5236 | 201968_s_at | -0.4882 | 0.1370 | |
| GSE20347 | PGM1 | 5236 | 201968_s_at | -0.9762 | 0.0000 | |
| GSE23400 | PGM1 | 5236 | 201968_s_at | -0.4585 | 0.0000 | |
| GSE26886 | PGM1 | 5236 | 201968_s_at | -0.5164 | 0.0237 | |
| GSE29001 | PGM1 | 5236 | 201968_s_at | -0.6799 | 0.0366 | |
| GSE38129 | PGM1 | 5236 | 201968_s_at | -0.8540 | 0.0000 | |
| GSE45670 | PGM1 | 5236 | 201968_s_at | -0.7945 | 0.0003 | |
| GSE53622 | PGM1 | 5236 | 81231 | -0.3541 | 0.0000 | |
| GSE53624 | PGM1 | 5236 | 81231 | -0.5117 | 0.0000 | |
| GSE63941 | PGM1 | 5236 | 201968_s_at | -0.5227 | 0.4650 | |
| GSE77861 | PGM1 | 5236 | 201968_s_at | -1.2905 | 0.0011 | |
| GSE97050 | PGM1 | 5236 | A_23_P52031 | -0.1690 | 0.3789 | |
| SRP007169 | PGM1 | 5236 | RNAseq | -1.0921 | 0.0106 | |
| SRP008496 | PGM1 | 5236 | RNAseq | -0.9714 | 0.0006 | |
| SRP064894 | PGM1 | 5236 | RNAseq | -0.2927 | 0.1094 | |
| SRP133303 | PGM1 | 5236 | RNAseq | -0.3197 | 0.1092 | |
| SRP159526 | PGM1 | 5236 | RNAseq | -0.8865 | 0.0005 | |
| SRP193095 | PGM1 | 5236 | RNAseq | -0.9660 | 0.0000 | |
| SRP219564 | PGM1 | 5236 | RNAseq | -0.5240 | 0.2264 | |
| TCGA | PGM1 | 5236 | RNAseq | -0.2069 | 0.0013 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PGM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PGM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PGM1 | 5236 | 3 | 6 | 21 | |
| GSE20123 | PGM1 | 5236 | 3 | 5 | 22 | |
| GSE43470 | PGM1 | 5236 | 5 | 4 | 34 | |
| GSE46452 | PGM1 | 5236 | 1 | 1 | 57 | |
| GSE47630 | PGM1 | 5236 | 8 | 5 | 27 | |
| GSE54993 | PGM1 | 5236 | 0 | 0 | 70 | |
| GSE54994 | PGM1 | 5236 | 6 | 5 | 42 | |
| GSE60625 | PGM1 | 5236 | 0 | 0 | 11 | |
| GSE74703 | PGM1 | 5236 | 4 | 3 | 29 | |
| GSE74704 | PGM1 | 5236 | 2 | 2 | 16 | |
| TCGA | PGM1 | 5236 | 10 | 20 | 66 |
Total number of gains: 42; Total number of losses: 51; Total Number of normals: 395.
Somatic mutations of PGM1:
Generating mutation plots.
Highly correlated genes for PGM1:
Showing top 20/1094 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PGM1 | TBCK | 0.807571 | 3 | 0 | 3 |
| PGM1 | PDCD7 | 0.755742 | 3 | 0 | 3 |
| PGM1 | ZCCHC9 | 0.75527 | 3 | 0 | 3 |
| PGM1 | UBQLN1 | 0.74623 | 3 | 0 | 3 |
| PGM1 | CYYR1 | 0.743855 | 3 | 0 | 3 |
| PGM1 | BDP1 | 0.740882 | 3 | 0 | 3 |
| PGM1 | LRP11 | 0.73506 | 3 | 0 | 3 |
| PGM1 | SLC16A14 | 0.732035 | 3 | 0 | 3 |
| PGM1 | TMEM219 | 0.730905 | 4 | 0 | 4 |
| PGM1 | PPIL3 | 0.730504 | 3 | 0 | 3 |
| PGM1 | HOXC5 | 0.724979 | 3 | 0 | 3 |
| PGM1 | DLL1 | 0.720008 | 3 | 0 | 3 |
| PGM1 | PRDX4 | 0.717696 | 3 | 0 | 3 |
| PGM1 | PPP2CB | 0.717306 | 7 | 0 | 7 |
| PGM1 | ZNF436 | 0.714858 | 5 | 0 | 4 |
| PGM1 | ARSG | 0.711547 | 3 | 0 | 3 |
| PGM1 | ALDOC | 0.710514 | 3 | 0 | 3 |
| PGM1 | TMEM61 | 0.707152 | 4 | 0 | 4 |
| PGM1 | NFIA | 0.698793 | 6 | 0 | 6 |
| PGM1 | GTF3C6 | 0.693959 | 4 | 0 | 4 |
For details and further investigation, click here
