| Full name: protein phosphatase 3 catalytic subunit gamma | Alias Symbol: CALNA3|PP2Bgamma | ||
| Type: protein-coding gene | Cytoband: 8p21.3 | ||
| Entrez ID: 5533 | HGNC ID: HGNC:9316 | Ensembl Gene: ENSG00000120910 | OMIM ID: 114107 |
| Drug and gene relationship at DGIdb | |||
PPP3CC involved pathways:
Expression of PPP3CC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP3CC | 5533 | 207000_s_at | -0.5956 | 0.0523 | |
| GSE20347 | PPP3CC | 5533 | 32541_at | -0.2332 | 0.1074 | |
| GSE23400 | PPP3CC | 5533 | 32540_at | -0.1245 | 0.0001 | |
| GSE26886 | PPP3CC | 5533 | 32541_at | -0.1858 | 0.4650 | |
| GSE29001 | PPP3CC | 5533 | 32541_at | -0.1567 | 0.4293 | |
| GSE38129 | PPP3CC | 5533 | 207000_s_at | -0.4606 | 0.0003 | |
| GSE45670 | PPP3CC | 5533 | 207000_s_at | -0.6099 | 0.0001 | |
| GSE63941 | PPP3CC | 5533 | 207000_s_at | -2.0256 | 0.0012 | |
| GSE77861 | PPP3CC | 5533 | 207000_s_at | -0.2558 | 0.0843 | |
| GSE97050 | PPP3CC | 5533 | A_23_P157495 | -0.1232 | 0.6057 | |
| SRP007169 | PPP3CC | 5533 | RNAseq | -0.8634 | 0.0267 | |
| SRP008496 | PPP3CC | 5533 | RNAseq | -0.7188 | 0.0054 | |
| SRP064894 | PPP3CC | 5533 | RNAseq | -0.3355 | 0.0622 | |
| SRP133303 | PPP3CC | 5533 | RNAseq | -0.4219 | 0.0351 | |
| SRP159526 | PPP3CC | 5533 | RNAseq | -0.6912 | 0.0002 | |
| SRP193095 | PPP3CC | 5533 | RNAseq | -0.3082 | 0.0216 | |
| SRP219564 | PPP3CC | 5533 | RNAseq | -0.1418 | 0.6321 | |
| TCGA | PPP3CC | 5533 | RNAseq | -0.2039 | 0.0013 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PPP3CC expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PPP3CC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP3CC | 5533 | 4 | 10 | 16 | |
| GSE20123 | PPP3CC | 5533 | 4 | 10 | 16 | |
| GSE43470 | PPP3CC | 5533 | 4 | 9 | 30 | |
| GSE46452 | PPP3CC | 5533 | 13 | 13 | 33 | |
| GSE47630 | PPP3CC | 5533 | 10 | 8 | 22 | |
| GSE54993 | PPP3CC | 5533 | 2 | 14 | 54 | |
| GSE54994 | PPP3CC | 5533 | 9 | 17 | 27 | |
| GSE60625 | PPP3CC | 5533 | 3 | 0 | 8 | |
| GSE74703 | PPP3CC | 5533 | 4 | 7 | 25 | |
| GSE74704 | PPP3CC | 5533 | 3 | 7 | 10 | |
| TCGA | PPP3CC | 5533 | 14 | 43 | 39 |
Total number of gains: 70; Total number of losses: 138; Total Number of normals: 280.
Somatic mutations of PPP3CC:
Generating mutation plots.
Highly correlated genes for PPP3CC:
Showing top 20/634 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP3CC | SUCLG1 | 0.790209 | 3 | 0 | 3 |
| PPP3CC | KIAA0895L | 0.771054 | 3 | 0 | 3 |
| PPP3CC | MBLAC1 | 0.770596 | 3 | 0 | 3 |
| PPP3CC | HOOK3 | 0.765074 | 6 | 0 | 6 |
| PPP3CC | KLHL9 | 0.760166 | 3 | 0 | 3 |
| PPP3CC | OR7A10 | 0.759426 | 3 | 0 | 3 |
| PPP3CC | TMEM38A | 0.759027 | 3 | 0 | 3 |
| PPP3CC | JMJD1C | 0.755596 | 3 | 0 | 3 |
| PPP3CC | IGFBP5 | 0.755521 | 3 | 0 | 3 |
| PPP3CC | IQGAP1 | 0.747544 | 4 | 0 | 4 |
| PPP3CC | UTRN | 0.743549 | 3 | 0 | 3 |
| PPP3CC | STT3B | 0.740319 | 3 | 0 | 3 |
| PPP3CC | CLIP4 | 0.738621 | 3 | 0 | 3 |
| PPP3CC | PRR16 | 0.732196 | 3 | 0 | 3 |
| PPP3CC | GHITM | 0.725385 | 3 | 0 | 3 |
| PPP3CC | HOXC5 | 0.722901 | 3 | 0 | 3 |
| PPP3CC | ULK3 | 0.722404 | 3 | 0 | 3 |
| PPP3CC | CRIM1 | 0.715988 | 3 | 0 | 3 |
| PPP3CC | CD109 | 0.714577 | 3 | 0 | 3 |
| PPP3CC | RARS2 | 0.712957 | 4 | 0 | 3 |
For details and further investigation, click here
