| Full name: haptoglobin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q22.2 | ||
| Entrez ID: 3240 | HGNC ID: HGNC:5141 | Ensembl Gene: ENSG00000257017 | OMIM ID: 140100 |
| Drug and gene relationship at DGIdb | |||
Expression of HP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HP | 3240 | 206697_s_at | -0.0274 | 0.9645 | |
| GSE20347 | HP | 3240 | 206697_s_at | 0.0388 | 0.5974 | |
| GSE23400 | HP | 3240 | 206697_s_at | -0.1111 | 0.0003 | |
| GSE26886 | HP | 3240 | 206697_s_at | 0.2234 | 0.1564 | |
| GSE29001 | HP | 3240 | 206697_s_at | -0.0622 | 0.6062 | |
| GSE38129 | HP | 3240 | 206697_s_at | -0.0682 | 0.4227 | |
| GSE45670 | HP | 3240 | 206697_s_at | -0.0515 | 0.6417 | |
| GSE63941 | HP | 3240 | 206697_s_at | 0.1046 | 0.5082 | |
| GSE77861 | HP | 3240 | 206697_s_at | 0.3464 | 0.5822 | |
| GSE97050 | HP | 3240 | A_23_P206760 | 0.2806 | 0.4485 | |
| SRP133303 | HP | 3240 | RNAseq | -0.6314 | 0.0862 | |
| TCGA | HP | 3240 | RNAseq | -0.7101 | 0.4479 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HP expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of HP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HP | 3240 | 4 | 0 | 26 | |
| GSE20123 | HP | 3240 | 4 | 0 | 26 | |
| GSE43470 | HP | 3240 | 2 | 8 | 33 | |
| GSE46452 | HP | 3240 | 38 | 2 | 19 | |
| GSE47630 | HP | 3240 | 11 | 8 | 21 | |
| GSE54993 | HP | 3240 | 2 | 4 | 64 | |
| GSE54994 | HP | 3240 | 8 | 10 | 35 | |
| GSE60625 | HP | 3240 | 4 | 0 | 7 | |
| GSE74703 | HP | 3240 | 2 | 5 | 29 | |
| GSE74704 | HP | 3240 | 2 | 0 | 18 | |
| TCGA | HP | 3240 | 25 | 15 | 56 |
Total number of gains: 102; Total number of losses: 52; Total Number of normals: 334.
Somatic mutations of HP:
Generating mutation plots.
Highly correlated genes for HP:
Showing top 20/309 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HP | C20orf85 | 0.725435 | 3 | 0 | 3 |
| HP | PTPRH | 0.693784 | 3 | 0 | 3 |
| HP | HARBI1 | 0.652756 | 3 | 0 | 3 |
| HP | POU1F1 | 0.65173 | 4 | 0 | 4 |
| HP | PSORS1C2 | 0.646584 | 4 | 0 | 3 |
| HP | IL9R | 0.644602 | 5 | 0 | 3 |
| HP | FBXO22 | 0.637603 | 3 | 0 | 3 |
| HP | TONSL | 0.637255 | 4 | 0 | 3 |
| HP | DLX6 | 0.637114 | 4 | 0 | 3 |
| HP | CAMKV | 0.630332 | 3 | 0 | 3 |
| HP | IL1RAPL1 | 0.629721 | 3 | 0 | 3 |
| HP | CDHR5 | 0.625581 | 4 | 0 | 4 |
| HP | KIR2DS3 | 0.625286 | 5 | 0 | 3 |
| HP | SLC5A5 | 0.623934 | 5 | 0 | 4 |
| HP | SLC22A13 | 0.620232 | 5 | 0 | 4 |
| HP | NEUROG2 | 0.619133 | 3 | 0 | 3 |
| HP | ALPL | 0.616261 | 4 | 0 | 3 |
| HP | DNAH2 | 0.613157 | 4 | 0 | 3 |
| HP | KRT20 | 0.610676 | 4 | 0 | 4 |
| HP | GPRC5D | 0.60989 | 5 | 0 | 4 |
For details and further investigation, click here
