| Full name: killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 3 | Alias Symbol: nkat7 | ||
| Type: protein-coding gene | Cytoband: 19q13.4 alternate reference locus | ||
| Entrez ID: 3808 | HGNC ID: HGNC:6335 | Ensembl Gene: | OMIM ID: 604954 |
| Drug and gene relationship at DGIdb | |||
KIR2DS3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04612 | Antigen processing and presentation | |
| hsa04650 | Natural killer cell mediated cytotoxicity |
Expression of KIR2DS3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIR2DS3 | 3808 | 208122_x_at | 0.0101 | 0.9799 | |
| GSE20347 | KIR2DS3 | 3808 | 208122_x_at | 0.0457 | 0.6762 | |
| GSE23400 | KIR2DS3 | 3808 | 208122_x_at | -0.1620 | 0.0009 | |
| GSE26886 | KIR2DS3 | 3808 | 208122_x_at | 0.0200 | 0.8700 | |
| GSE29001 | KIR2DS3 | 3808 | 208122_x_at | -0.0979 | 0.5855 | |
| GSE38129 | KIR2DS3 | 3808 | 208122_x_at | -0.0482 | 0.7021 | |
| GSE45670 | KIR2DS3 | 3808 | 208122_x_at | 0.1129 | 0.2693 | |
| GSE63941 | KIR2DS3 | 3808 | 208122_x_at | 0.1596 | 0.3562 | |
| GSE77861 | KIR2DS3 | 3808 | 208122_x_at | 0.0506 | 0.6802 | |
| GSE97050 | KIR2DS3 | 3808 | A_33_P3311073 | 0.7672 | 0.2816 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of KIR2DS3:
No record found for this gene.
Somatic mutations of KIR2DS3:
Generating mutation plots.
Highly correlated genes for KIR2DS3:
Showing top 20/1021 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIR2DS3 | IL1RAPL2 | 0.749209 | 5 | 0 | 5 |
| KIR2DS3 | TCL6 | 0.74597 | 3 | 0 | 3 |
| KIR2DS3 | CGA | 0.734312 | 5 | 0 | 5 |
| KIR2DS3 | RSPH6A | 0.731252 | 6 | 0 | 6 |
| KIR2DS3 | ECE2 | 0.723805 | 5 | 0 | 5 |
| KIR2DS3 | CHGA | 0.723306 | 4 | 0 | 4 |
| KIR2DS3 | NTNG1 | 0.719061 | 4 | 0 | 4 |
| KIR2DS3 | RAI1 | 0.718581 | 5 | 0 | 5 |
| KIR2DS3 | KRT38 | 0.718399 | 4 | 0 | 4 |
| KIR2DS3 | ASTN1 | 0.716562 | 3 | 0 | 3 |
| KIR2DS3 | CRHR2 | 0.707363 | 5 | 0 | 5 |
| KIR2DS3 | GPA33 | 0.706055 | 4 | 0 | 4 |
| KIR2DS3 | PAPPA2 | 0.70513 | 6 | 0 | 5 |
| KIR2DS3 | GBX1 | 0.703727 | 5 | 0 | 5 |
| KIR2DS3 | SLC17A1 | 0.701588 | 4 | 0 | 4 |
| KIR2DS3 | FCGR2C | 0.701552 | 3 | 0 | 3 |
| KIR2DS3 | ELSPBP1 | 0.700227 | 4 | 0 | 4 |
| KIR2DS3 | P2RX6 | 0.699959 | 5 | 0 | 4 |
| KIR2DS3 | NEU3 | 0.699615 | 5 | 0 | 5 |
| KIR2DS3 | CCDC87 | 0.697846 | 4 | 0 | 4 |
For details and further investigation, click here
