| Full name: neurogenin 2 | Alias Symbol: Atoh4|Math4A|ngn-2|bHLHa8|NGN2 | ||
| Type: protein-coding gene | Cytoband: 4q25 | ||
| Entrez ID: 63973 | HGNC ID: HGNC:13805 | Ensembl Gene: ENSG00000178403 | OMIM ID: 606624 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NEUROG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEUROG2 | 63973 | 215632_at | 0.0219 | 0.9361 | |
| GSE20347 | NEUROG2 | 63973 | 215632_at | 0.0201 | 0.7366 | |
| GSE23400 | NEUROG2 | 63973 | 215632_at | -0.0287 | 0.2064 | |
| GSE26886 | NEUROG2 | 63973 | 215632_at | 0.2095 | 0.1531 | |
| GSE29001 | NEUROG2 | 63973 | 215632_at | 0.0158 | 0.8802 | |
| GSE38129 | NEUROG2 | 63973 | 215632_at | 0.0228 | 0.6579 | |
| GSE45670 | NEUROG2 | 63973 | 215632_at | 0.0842 | 0.2269 | |
| GSE53622 | NEUROG2 | 63973 | 12732 | 0.1933 | 0.2889 | |
| GSE53624 | NEUROG2 | 63973 | 12732 | 0.6377 | 0.0000 | |
| GSE63941 | NEUROG2 | 63973 | 215632_at | -0.0090 | 0.9612 | |
| GSE77861 | NEUROG2 | 63973 | 215632_at | -0.1042 | 0.4278 | |
| TCGA | NEUROG2 | 63973 | RNAseq | 3.6227 | 0.0031 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NEUROG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEUROG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEUROG2 | 63973 | 1 | 13 | 16 | |
| GSE20123 | NEUROG2 | 63973 | 1 | 13 | 16 | |
| GSE43470 | NEUROG2 | 63973 | 0 | 14 | 29 | |
| GSE46452 | NEUROG2 | 63973 | 1 | 36 | 22 | |
| GSE47630 | NEUROG2 | 63973 | 0 | 20 | 20 | |
| GSE54993 | NEUROG2 | 63973 | 9 | 0 | 61 | |
| GSE54994 | NEUROG2 | 63973 | 1 | 11 | 41 | |
| GSE60625 | NEUROG2 | 63973 | 0 | 3 | 8 | |
| GSE74703 | NEUROG2 | 63973 | 0 | 12 | 24 | |
| GSE74704 | NEUROG2 | 63973 | 0 | 7 | 13 | |
| TCGA | NEUROG2 | 63973 | 8 | 35 | 53 |
Total number of gains: 21; Total number of losses: 164; Total Number of normals: 303.
Somatic mutations of NEUROG2:
Generating mutation plots.
Highly correlated genes for NEUROG2:
Showing top 20/200 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEUROG2 | PTPRCAP | 0.658736 | 3 | 0 | 3 |
| NEUROG2 | BLK | 0.658681 | 4 | 0 | 3 |
| NEUROG2 | SHANK1 | 0.653138 | 4 | 0 | 4 |
| NEUROG2 | CD180 | 0.652516 | 4 | 0 | 4 |
| NEUROG2 | IL9R | 0.648266 | 5 | 0 | 3 |
| NEUROG2 | UBASH3B | 0.630211 | 3 | 0 | 3 |
| NEUROG2 | NAGLU | 0.626357 | 4 | 0 | 3 |
| NEUROG2 | PHACTR1 | 0.622519 | 4 | 0 | 3 |
| NEUROG2 | LINC00950 | 0.619898 | 3 | 0 | 3 |
| NEUROG2 | HP | 0.619133 | 3 | 0 | 3 |
| NEUROG2 | DMP1 | 0.617974 | 3 | 0 | 3 |
| NEUROG2 | DGKZ | 0.61513 | 3 | 0 | 3 |
| NEUROG2 | YTHDF3-AS1 | 0.61306 | 3 | 0 | 3 |
| NEUROG2 | TMEM179 | 0.606074 | 4 | 0 | 3 |
| NEUROG2 | METRN | 0.605905 | 3 | 0 | 3 |
| NEUROG2 | RGS9 | 0.605367 | 5 | 0 | 3 |
| NEUROG2 | CXCR1 | 0.605082 | 3 | 0 | 3 |
| NEUROG2 | SH2D1A | 0.605043 | 4 | 0 | 3 |
| NEUROG2 | FBXO31 | 0.604495 | 3 | 0 | 3 |
| NEUROG2 | NTRK1 | 0.603295 | 4 | 0 | 3 |
For details and further investigation, click here
