| Full name: psoriasis susceptibility 1 candidate 2 | Alias Symbol: SPR1 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 170680 | HGNC ID: HGNC:17199 | Ensembl Gene: ENSG00000204538 | OMIM ID: 613526 |
| Drug and gene relationship at DGIdb | |||
Expression of PSORS1C2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSORS1C2 | 170680 | 220635_at | -0.1518 | 0.8100 | |
| GSE20347 | PSORS1C2 | 170680 | 220635_at | -0.2190 | 0.0502 | |
| GSE23400 | PSORS1C2 | 170680 | 220635_at | -0.2131 | 0.0004 | |
| GSE26886 | PSORS1C2 | 170680 | 220635_at | -0.2983 | 0.1793 | |
| GSE29001 | PSORS1C2 | 170680 | 220635_at | -0.6376 | 0.0285 | |
| GSE38129 | PSORS1C2 | 170680 | 220635_at | -0.3046 | 0.0389 | |
| GSE45670 | PSORS1C2 | 170680 | 220635_at | -0.0291 | 0.9201 | |
| GSE63941 | PSORS1C2 | 170680 | 220635_at | -0.0407 | 0.7853 | |
| GSE77861 | PSORS1C2 | 170680 | 220635_at | 0.0056 | 0.9883 | |
| TCGA | PSORS1C2 | 170680 | RNAseq | 0.3601 | 0.4212 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSORS1C2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PSORS1C2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSORS1C2 | 170680 | 5 | 1 | 24 | |
| GSE20123 | PSORS1C2 | 170680 | 5 | 1 | 24 | |
| GSE43470 | PSORS1C2 | 170680 | 5 | 1 | 37 | |
| GSE46452 | PSORS1C2 | 170680 | 1 | 10 | 48 | |
| GSE47630 | PSORS1C2 | 170680 | 7 | 3 | 30 | |
| GSE54993 | PSORS1C2 | 170680 | 2 | 1 | 67 | |
| GSE54994 | PSORS1C2 | 170680 | 11 | 4 | 38 | |
| GSE60625 | PSORS1C2 | 170680 | 0 | 1 | 10 | |
| GSE74703 | PSORS1C2 | 170680 | 5 | 0 | 31 | |
| GSE74704 | PSORS1C2 | 170680 | 2 | 0 | 18 | |
| TCGA | PSORS1C2 | 170680 | 17 | 16 | 63 |
Total number of gains: 60; Total number of losses: 38; Total Number of normals: 390.
Somatic mutations of PSORS1C2:
Generating mutation plots.
Highly correlated genes for PSORS1C2:
Showing top 20/162 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSORS1C2 | TM6SF2 | 0.678247 | 3 | 0 | 3 |
| PSORS1C2 | MEPE | 0.674527 | 3 | 0 | 3 |
| PSORS1C2 | LINC01136 | 0.658385 | 3 | 0 | 3 |
| PSORS1C2 | HP | 0.646584 | 4 | 0 | 3 |
| PSORS1C2 | ARMC4 | 0.646447 | 3 | 0 | 3 |
| PSORS1C2 | CTSG | 0.638811 | 3 | 0 | 3 |
| PSORS1C2 | APOA4 | 0.637247 | 3 | 0 | 3 |
| PSORS1C2 | MASP2 | 0.636356 | 3 | 0 | 3 |
| PSORS1C2 | FOXN1 | 0.610661 | 4 | 0 | 3 |
| PSORS1C2 | ZBTB7C | 0.610026 | 3 | 0 | 3 |
| PSORS1C2 | HPGDS | 0.609201 | 4 | 0 | 3 |
| PSORS1C2 | SLC38A3 | 0.608409 | 3 | 0 | 3 |
| PSORS1C2 | RAX | 0.607292 | 4 | 0 | 3 |
| PSORS1C2 | CETN1 | 0.603604 | 4 | 0 | 3 |
| PSORS1C2 | MTNR1B | 0.601606 | 4 | 0 | 3 |
| PSORS1C2 | RARG | 0.599542 | 5 | 0 | 4 |
| PSORS1C2 | TERT | 0.596647 | 3 | 0 | 3 |
| PSORS1C2 | RECQL5 | 0.593047 | 5 | 0 | 4 |
| PSORS1C2 | PRL | 0.59287 | 4 | 0 | 3 |
| PSORS1C2 | SLC22A8 | 0.590004 | 4 | 0 | 3 |
For details and further investigation, click here
