| Full name: protein tyrosine phosphatase receptor type H | Alias Symbol: SAP-1 | ||
| Type: protein-coding gene | Cytoband: 19q13.4 | ||
| Entrez ID: 5794 | HGNC ID: HGNC:9672 | Ensembl Gene: | OMIM ID: 602510 |
| Drug and gene relationship at DGIdb | |||
Expression of PTPRH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTPRH | 5794 | 208300_at | 0.2810 | 0.3384 | |
| GSE20347 | PTPRH | 5794 | 208300_at | 0.1803 | 0.0225 | |
| GSE23400 | PTPRH | 5794 | 208300_at | 0.0213 | 0.6920 | |
| GSE26886 | PTPRH | 5794 | 208300_at | 0.5660 | 0.0084 | |
| GSE29001 | PTPRH | 5794 | 208300_at | 0.2580 | 0.2795 | |
| GSE38129 | PTPRH | 5794 | 208300_at | 0.1698 | 0.1365 | |
| GSE45670 | PTPRH | 5794 | 208300_at | 0.7116 | 0.0005 | |
| GSE53622 | PTPRH | 5794 | 47975 | 0.2751 | 0.0553 | |
| GSE53624 | PTPRH | 5794 | 47975 | -0.4664 | 0.0006 | |
| GSE63941 | PTPRH | 5794 | 208300_at | 0.5908 | 0.1815 | |
| GSE77861 | PTPRH | 5794 | 208300_at | 0.0316 | 0.9130 | |
| GSE97050 | PTPRH | 5794 | A_23_P101642 | 0.5866 | 0.1851 | |
| SRP133303 | PTPRH | 5794 | RNAseq | 3.6025 | 0.0000 | |
| SRP219564 | PTPRH | 5794 | RNAseq | 4.1738 | 0.0001 | |
| TCGA | PTPRH | 5794 | RNAseq | -1.2100 | 0.0002 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by PTPRH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTPRH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTPRH | 5794 | 3 | 4 | 23 | |
| GSE20123 | PTPRH | 5794 | 3 | 3 | 24 | |
| GSE43470 | PTPRH | 5794 | 3 | 11 | 29 | |
| GSE46452 | PTPRH | 5794 | 45 | 1 | 13 | |
| GSE47630 | PTPRH | 5794 | 8 | 6 | 26 | |
| GSE54993 | PTPRH | 5794 | 17 | 4 | 49 | |
| GSE54994 | PTPRH | 5794 | 4 | 13 | 36 | |
| GSE60625 | PTPRH | 5794 | 9 | 0 | 2 | |
| GSE74703 | PTPRH | 5794 | 3 | 7 | 26 | |
| GSE74704 | PTPRH | 5794 | 3 | 1 | 16 | |
| TCGA | PTPRH | 5794 | 19 | 14 | 63 |
Total number of gains: 117; Total number of losses: 64; Total Number of normals: 307.
Somatic mutations of PTPRH:
Generating mutation plots.
Highly correlated genes for PTPRH:
Showing top 20/293 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTPRH | CCNJL | 0.74231 | 4 | 0 | 4 |
| PTPRH | MAPK15 | 0.730301 | 3 | 0 | 3 |
| PTPRH | HSPBAP1 | 0.724373 | 3 | 0 | 3 |
| PTPRH | C19orf81 | 0.717425 | 3 | 0 | 3 |
| PTPRH | WRAP73 | 0.715117 | 3 | 0 | 3 |
| PTPRH | CLTCL1 | 0.709875 | 3 | 0 | 3 |
| PTPRH | SERPINA10 | 0.699472 | 3 | 0 | 3 |
| PTPRH | HP | 0.693784 | 3 | 0 | 3 |
| PTPRH | POLD1 | 0.693503 | 3 | 0 | 3 |
| PTPRH | TMEM120B | 0.69103 | 3 | 0 | 3 |
| PTPRH | COL27A1 | 0.689361 | 4 | 0 | 3 |
| PTPRH | TYMP | 0.68486 | 3 | 0 | 3 |
| PTPRH | MAK | 0.683369 | 3 | 0 | 3 |
| PTPRH | DUSP9 | 0.681923 | 5 | 0 | 4 |
| PTPRH | OLIG3 | 0.677601 | 4 | 0 | 4 |
| PTPRH | CENPW | 0.677189 | 3 | 0 | 3 |
| PTPRH | UHRF1 | 0.67548 | 3 | 0 | 3 |
| PTPRH | WDR90 | 0.672173 | 5 | 0 | 4 |
| PTPRH | FEN1 | 0.670389 | 4 | 0 | 4 |
| PTPRH | NPW | 0.667088 | 4 | 0 | 3 |
For details and further investigation, click here
