| Full name: dynein axonemal heavy chain 2 | Alias Symbol: KIAA1503|FLJ46675 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 146754 | HGNC ID: HGNC:2948 | Ensembl Gene: ENSG00000183914 | OMIM ID: 603333 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAH2 | 146754 | 239499_at | 0.7540 | 0.0805 | |
| GSE20347 | DNAH2 | 146754 | 215840_at | 0.0130 | 0.8997 | |
| GSE23400 | DNAH2 | 146754 | 215840_at | -0.2840 | 0.0000 | |
| GSE26886 | DNAH2 | 146754 | 239499_at | 0.4531 | 0.0083 | |
| GSE29001 | DNAH2 | 146754 | 215840_at | -0.0813 | 0.5484 | |
| GSE38129 | DNAH2 | 146754 | 215840_at | -0.0371 | 0.7154 | |
| GSE45670 | DNAH2 | 146754 | 239499_at | 0.1986 | 0.2688 | |
| GSE53622 | DNAH2 | 146754 | 102185 | 0.7464 | 0.0000 | |
| GSE53624 | DNAH2 | 146754 | 102185 | 0.7361 | 0.0000 | |
| GSE63941 | DNAH2 | 146754 | 239499_at | 0.3605 | 0.2577 | |
| GSE77861 | DNAH2 | 146754 | 239499_at | 0.0755 | 0.7635 | |
| GSE97050 | DNAH2 | 146754 | A_32_P206899 | 0.3041 | 0.2782 | |
| SRP133303 | DNAH2 | 146754 | RNAseq | 0.5464 | 0.0015 | |
| SRP159526 | DNAH2 | 146754 | RNAseq | 1.7371 | 0.0000 | |
| SRP193095 | DNAH2 | 146754 | RNAseq | 0.6596 | 0.0032 | |
| SRP219564 | DNAH2 | 146754 | RNAseq | 0.9678 | 0.0829 | |
| TCGA | DNAH2 | 146754 | RNAseq | 0.9722 | 0.0282 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DNAH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAH2 | 146754 | 4 | 2 | 24 | |
| GSE20123 | DNAH2 | 146754 | 4 | 3 | 23 | |
| GSE43470 | DNAH2 | 146754 | 1 | 6 | 36 | |
| GSE46452 | DNAH2 | 146754 | 34 | 1 | 24 | |
| GSE47630 | DNAH2 | 146754 | 7 | 1 | 32 | |
| GSE54993 | DNAH2 | 146754 | 4 | 3 | 63 | |
| GSE54994 | DNAH2 | 146754 | 5 | 8 | 40 | |
| GSE60625 | DNAH2 | 146754 | 4 | 0 | 7 | |
| GSE74703 | DNAH2 | 146754 | 1 | 3 | 32 | |
| GSE74704 | DNAH2 | 146754 | 2 | 1 | 17 | |
| TCGA | DNAH2 | 146754 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 49; Total Number of normals: 356.
Somatic mutations of DNAH2:
Generating mutation plots.
Highly correlated genes for DNAH2:
Showing top 20/415 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAH2 | ARL9 | 0.729006 | 3 | 0 | 3 |
| DNAH2 | KCNAB3 | 0.709859 | 3 | 0 | 3 |
| DNAH2 | CDH4 | 0.709335 | 3 | 0 | 3 |
| DNAH2 | TMEM9 | 0.705785 | 3 | 0 | 3 |
| DNAH2 | ELOVL3 | 0.69823 | 4 | 0 | 4 |
| DNAH2 | AICDA | 0.679499 | 4 | 0 | 3 |
| DNAH2 | RAX | 0.663827 | 3 | 0 | 3 |
| DNAH2 | PTCH2 | 0.662717 | 5 | 0 | 4 |
| DNAH2 | HAGHL | 0.660148 | 4 | 0 | 3 |
| DNAH2 | CDRT15 | 0.652302 | 3 | 0 | 3 |
| DNAH2 | PPFIA2 | 0.651725 | 3 | 0 | 3 |
| DNAH2 | STRC | 0.645107 | 3 | 0 | 3 |
| DNAH2 | NTNG2 | 0.643115 | 3 | 0 | 3 |
| DNAH2 | RTN4RL2 | 0.642535 | 3 | 0 | 3 |
| DNAH2 | ZNF77 | 0.642281 | 4 | 0 | 4 |
| DNAH2 | DEFB121 | 0.638532 | 3 | 0 | 3 |
| DNAH2 | ARR3 | 0.638303 | 3 | 0 | 3 |
| DNAH2 | S1PR4 | 0.637283 | 4 | 0 | 3 |
| DNAH2 | KCNH3 | 0.636912 | 4 | 0 | 4 |
| DNAH2 | TMEM105 | 0.636122 | 3 | 0 | 3 |
For details and further investigation, click here
