| Full name: transmembrane 6 superfamily member 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q25.2 | ||
| Entrez ID: 53346 | HGNC ID: HGNC:11860 | Ensembl Gene: ENSG00000136404 | OMIM ID: 606562 |
| Drug and gene relationship at DGIdb | |||
Expression of TM6SF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TM6SF1 | 53346 | 219892_at | -0.4698 | 0.4649 | |
| GSE20347 | TM6SF1 | 53346 | 219892_at | 0.0739 | 0.3885 | |
| GSE23400 | TM6SF1 | 53346 | 219892_at | -0.0444 | 0.4099 | |
| GSE26886 | TM6SF1 | 53346 | 219892_at | -0.4471 | 0.0051 | |
| GSE29001 | TM6SF1 | 53346 | 219892_at | 0.0445 | 0.8017 | |
| GSE38129 | TM6SF1 | 53346 | 219892_at | 0.0322 | 0.8649 | |
| GSE45670 | TM6SF1 | 53346 | 219892_at | -0.9990 | 0.0000 | |
| GSE53622 | TM6SF1 | 53346 | 1921 | -0.1943 | 0.0174 | |
| GSE53624 | TM6SF1 | 53346 | 1921 | -0.1699 | 0.1338 | |
| GSE63941 | TM6SF1 | 53346 | 219892_at | 0.0720 | 0.9570 | |
| GSE77861 | TM6SF1 | 53346 | 219892_at | 0.0696 | 0.4296 | |
| GSE97050 | TM6SF1 | 53346 | A_23_P77117 | -0.1607 | 0.5354 | |
| SRP064894 | TM6SF1 | 53346 | RNAseq | 0.5475 | 0.1835 | |
| SRP133303 | TM6SF1 | 53346 | RNAseq | -0.0088 | 0.9698 | |
| SRP159526 | TM6SF1 | 53346 | RNAseq | 0.1075 | 0.8509 | |
| SRP193095 | TM6SF1 | 53346 | RNAseq | 0.1889 | 0.2665 | |
| SRP219564 | TM6SF1 | 53346 | RNAseq | -0.2362 | 0.5171 | |
| TCGA | TM6SF1 | 53346 | RNAseq | -0.0334 | 0.7977 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TM6SF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TM6SF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TM6SF1 | 53346 | 7 | 1 | 22 | |
| GSE20123 | TM6SF1 | 53346 | 7 | 1 | 22 | |
| GSE43470 | TM6SF1 | 53346 | 4 | 4 | 35 | |
| GSE46452 | TM6SF1 | 53346 | 3 | 7 | 49 | |
| GSE47630 | TM6SF1 | 53346 | 8 | 10 | 22 | |
| GSE54993 | TM6SF1 | 53346 | 5 | 6 | 59 | |
| GSE54994 | TM6SF1 | 53346 | 6 | 6 | 41 | |
| GSE60625 | TM6SF1 | 53346 | 4 | 0 | 7 | |
| GSE74703 | TM6SF1 | 53346 | 4 | 2 | 30 | |
| GSE74704 | TM6SF1 | 53346 | 3 | 1 | 16 | |
| TCGA | TM6SF1 | 53346 | 15 | 14 | 67 |
Total number of gains: 66; Total number of losses: 52; Total Number of normals: 370.
Somatic mutations of TM6SF1:
Generating mutation plots.
Highly correlated genes for TM6SF1:
Showing top 20/159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TM6SF1 | C16orf89 | 0.762346 | 3 | 0 | 3 |
| TM6SF1 | GPR146 | 0.738669 | 3 | 0 | 3 |
| TM6SF1 | HSPA12B | 0.704902 | 3 | 0 | 3 |
| TM6SF1 | FGD5 | 0.702952 | 4 | 0 | 3 |
| TM6SF1 | MAGI2-AS3 | 0.697952 | 4 | 0 | 4 |
| TM6SF1 | CNTN4 | 0.682604 | 3 | 0 | 3 |
| TM6SF1 | LDB2 | 0.674295 | 7 | 0 | 6 |
| TM6SF1 | JAM2 | 0.663873 | 7 | 0 | 7 |
| TM6SF1 | TCEAL7 | 0.659544 | 6 | 0 | 5 |
| TM6SF1 | ALKBH5 | 0.658943 | 4 | 0 | 3 |
| TM6SF1 | GSTM5 | 0.657977 | 4 | 0 | 3 |
| TM6SF1 | PABPC5 | 0.651773 | 4 | 0 | 3 |
| TM6SF1 | CPQ | 0.647252 | 6 | 0 | 6 |
| TM6SF1 | ZFPM2 | 0.645502 | 8 | 0 | 7 |
| TM6SF1 | CLEC4D | 0.643647 | 3 | 0 | 3 |
| TM6SF1 | SETDB2 | 0.640972 | 4 | 0 | 3 |
| TM6SF1 | ECM2 | 0.636132 | 9 | 0 | 8 |
| TM6SF1 | PCCA | 0.635831 | 4 | 0 | 4 |
| TM6SF1 | ADORA3 | 0.635191 | 4 | 0 | 4 |
| TM6SF1 | TESC | 0.62931 | 7 | 0 | 4 |
For details and further investigation, click here
