| Full name: crystallin beta A1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 1411 | HGNC ID: HGNC:2394 | Ensembl Gene: ENSG00000108255 | OMIM ID: 123610 |
| Drug and gene relationship at DGIdb | |||
Expression of CRYBA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRYBA1 | 1411 | 206982_at | -0.0566 | 0.7891 | |
| GSE20347 | CRYBA1 | 1411 | 206982_at | 0.1308 | 0.0331 | |
| GSE23400 | CRYBA1 | 1411 | 206982_at | 0.0002 | 0.9955 | |
| GSE26886 | CRYBA1 | 1411 | 206982_at | 0.3465 | 0.0016 | |
| GSE29001 | CRYBA1 | 1411 | 206982_at | 0.0226 | 0.8739 | |
| GSE38129 | CRYBA1 | 1411 | 206982_at | 0.0339 | 0.5627 | |
| GSE45670 | CRYBA1 | 1411 | 206982_at | -0.0179 | 0.8455 | |
| GSE53622 | CRYBA1 | 1411 | 49576 | -0.3291 | 0.0259 | |
| GSE53624 | CRYBA1 | 1411 | 49576 | -0.4593 | 0.0002 | |
| GSE63941 | CRYBA1 | 1411 | 206982_at | 0.1145 | 0.3596 | |
| GSE77861 | CRYBA1 | 1411 | 206982_at | 0.0053 | 0.9558 | |
| GSE97050 | CRYBA1 | 1411 | A_23_P4254 | -0.2601 | 0.3546 | |
| SRP133303 | CRYBA1 | 1411 | RNAseq | -0.5047 | 0.0924 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CRYBA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRYBA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRYBA1 | 1411 | 8 | 1 | 21 | |
| GSE20123 | CRYBA1 | 1411 | 9 | 1 | 20 | |
| GSE43470 | CRYBA1 | 1411 | 0 | 1 | 42 | |
| GSE46452 | CRYBA1 | 1411 | 33 | 1 | 25 | |
| GSE47630 | CRYBA1 | 1411 | 7 | 1 | 32 | |
| GSE54993 | CRYBA1 | 1411 | 2 | 3 | 65 | |
| GSE54994 | CRYBA1 | 1411 | 7 | 6 | 40 | |
| GSE60625 | CRYBA1 | 1411 | 4 | 0 | 7 | |
| GSE74703 | CRYBA1 | 1411 | 0 | 1 | 35 | |
| GSE74704 | CRYBA1 | 1411 | 6 | 1 | 13 | |
| TCGA | CRYBA1 | 1411 | 21 | 10 | 65 |
Total number of gains: 97; Total number of losses: 26; Total Number of normals: 365.
Somatic mutations of CRYBA1:
Generating mutation plots.
Highly correlated genes for CRYBA1:
Showing top 20/342 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRYBA1 | HTR1F | 0.783579 | 3 | 0 | 3 |
| CRYBA1 | ZMIZ2 | 0.75236 | 3 | 0 | 3 |
| CRYBA1 | NR5A2 | 0.750403 | 3 | 0 | 3 |
| CRYBA1 | CD180 | 0.740414 | 3 | 0 | 3 |
| CRYBA1 | NKX2-5 | 0.738708 | 3 | 0 | 3 |
| CRYBA1 | KLHL25 | 0.738297 | 3 | 0 | 3 |
| CRYBA1 | AKR1E2 | 0.736125 | 4 | 0 | 4 |
| CRYBA1 | LIPF | 0.725782 | 4 | 0 | 4 |
| CRYBA1 | BTBD2 | 0.71531 | 3 | 0 | 3 |
| CRYBA1 | NPFF | 0.708265 | 3 | 0 | 3 |
| CRYBA1 | FCHO1 | 0.706214 | 3 | 0 | 3 |
| CRYBA1 | C6orf163 | 0.702727 | 3 | 0 | 3 |
| CRYBA1 | MAGEC1 | 0.702307 | 3 | 0 | 3 |
| CRYBA1 | SLC25A12 | 0.695598 | 3 | 0 | 3 |
| CRYBA1 | KCNC4 | 0.685047 | 4 | 0 | 4 |
| CRYBA1 | IFNB1 | 0.679922 | 4 | 0 | 4 |
| CRYBA1 | ALPK3 | 0.678543 | 3 | 0 | 3 |
| CRYBA1 | MAST2 | 0.677373 | 3 | 0 | 3 |
| CRYBA1 | TWISTNB | 0.674112 | 3 | 0 | 3 |
| CRYBA1 | VWCE | 0.67222 | 3 | 0 | 3 |
For details and further investigation, click here
