| Full name: triggering receptor expressed on myeloid cells like 2 | Alias Symbol: FLJ13693|TLT2|dJ238O23.1 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 79865 | HGNC ID: HGNC:21092 | Ensembl Gene: ENSG00000112195 | OMIM ID: 609715 |
| Drug and gene relationship at DGIdb | |||
Expression of TREML2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TREML2 | 79865 | 219748_at | -0.1324 | 0.6462 | |
| GSE20347 | TREML2 | 79865 | 219748_at | -0.0778 | 0.4905 | |
| GSE23400 | TREML2 | 79865 | 219748_at | -0.3676 | 0.0000 | |
| GSE26886 | TREML2 | 79865 | 219748_at | -0.2803 | 0.0305 | |
| GSE29001 | TREML2 | 79865 | 219748_at | -0.1955 | 0.3077 | |
| GSE38129 | TREML2 | 79865 | 219748_at | -0.2595 | 0.0016 | |
| GSE45670 | TREML2 | 79865 | 219748_at | -0.1201 | 0.3368 | |
| GSE53622 | TREML2 | 79865 | 35520 | 0.0798 | 0.6220 | |
| GSE53624 | TREML2 | 79865 | 35520 | 0.1316 | 0.3573 | |
| GSE63941 | TREML2 | 79865 | 219748_at | 0.3303 | 0.0423 | |
| GSE77861 | TREML2 | 79865 | 219748_at | -0.1579 | 0.2495 | |
| SRP064894 | TREML2 | 79865 | RNAseq | 0.4850 | 0.0545 | |
| SRP133303 | TREML2 | 79865 | RNAseq | -0.0984 | 0.6135 | |
| SRP159526 | TREML2 | 79865 | RNAseq | -0.3337 | 0.6243 | |
| SRP193095 | TREML2 | 79865 | RNAseq | 0.9462 | 0.0000 | |
| SRP219564 | TREML2 | 79865 | RNAseq | 0.3609 | 0.5165 | |
| TCGA | TREML2 | 79865 | RNAseq | -0.3242 | 0.4902 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TREML2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TREML2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TREML2 | 79865 | 4 | 2 | 24 | |
| GSE20123 | TREML2 | 79865 | 4 | 2 | 24 | |
| GSE43470 | TREML2 | 79865 | 6 | 0 | 37 | |
| GSE46452 | TREML2 | 79865 | 2 | 9 | 48 | |
| GSE47630 | TREML2 | 79865 | 8 | 4 | 28 | |
| GSE54993 | TREML2 | 79865 | 3 | 2 | 65 | |
| GSE54994 | TREML2 | 79865 | 11 | 4 | 38 | |
| GSE60625 | TREML2 | 79865 | 0 | 1 | 10 | |
| GSE74703 | TREML2 | 79865 | 6 | 0 | 30 | |
| GSE74704 | TREML2 | 79865 | 2 | 2 | 16 | |
| TCGA | TREML2 | 79865 | 19 | 13 | 64 |
Total number of gains: 65; Total number of losses: 39; Total Number of normals: 384.
Somatic mutations of TREML2:
Generating mutation plots.
Highly correlated genes for TREML2:
Showing top 20/1295 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TREML2 | AKAP6 | 0.732074 | 4 | 0 | 4 |
| TREML2 | NPTXR | 0.727165 | 7 | 0 | 7 |
| TREML2 | SHANK1 | 0.720802 | 4 | 0 | 4 |
| TREML2 | MUC5AC | 0.710194 | 5 | 0 | 5 |
| TREML2 | MYO1A | 0.699866 | 7 | 0 | 7 |
| TREML2 | MATN1 | 0.692123 | 3 | 0 | 3 |
| TREML2 | DPYSL4 | 0.691433 | 7 | 0 | 7 |
| TREML2 | IQCD | 0.688053 | 3 | 0 | 3 |
| TREML2 | CAMK2B | 0.686182 | 6 | 0 | 6 |
| TREML2 | MAGEA8 | 0.683876 | 3 | 0 | 3 |
| TREML2 | GABRR2 | 0.683065 | 4 | 0 | 4 |
| TREML2 | MYF5 | 0.681761 | 3 | 0 | 3 |
| TREML2 | NCR2 | 0.68145 | 7 | 0 | 7 |
| TREML2 | PRODH2 | 0.679393 | 6 | 0 | 6 |
| TREML2 | GALNT8 | 0.677968 | 6 | 0 | 6 |
| TREML2 | TEK | 0.677647 | 3 | 0 | 3 |
| TREML2 | C3orf36 | 0.677616 | 5 | 0 | 5 |
| TREML2 | PSG5 | 0.673349 | 5 | 0 | 5 |
| TREML2 | NXPE4 | 0.672486 | 5 | 0 | 5 |
| TREML2 | SLC5A5 | 0.671073 | 5 | 0 | 5 |
For details and further investigation, click here
