| Full name: hydroxylysine kinase | Alias Symbol: LOC123688 | ||
| Type: protein-coding gene | Cytoband: 15q25.1 | ||
| Entrez ID: 123688 | HGNC ID: HGNC:34403 | Ensembl Gene: ENSG00000188266 | OMIM ID: 614681 |
Expression of HYKK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HYKK | 123688 | 236150_at | -0.2779 | 0.6279 | |
| GSE26886 | HYKK | 123688 | 236150_at | -0.1763 | 0.5084 | |
| GSE45670 | HYKK | 123688 | 236150_at | -0.4821 | 0.0091 | |
| GSE53622 | HYKK | 123688 | 155788 | -0.4856 | 0.0000 | |
| GSE53624 | HYKK | 123688 | 155788 | -0.6756 | 0.0000 | |
| GSE63941 | HYKK | 123688 | 236150_at | 0.4873 | 0.3608 | |
| GSE77861 | HYKK | 123688 | 236150_at | -0.3250 | 0.0886 | |
| SRP007169 | HYKK | 123688 | RNAseq | -0.7771 | 0.1584 | |
| SRP064894 | HYKK | 123688 | RNAseq | -0.6374 | 0.0236 | |
| SRP133303 | HYKK | 123688 | RNAseq | -0.2332 | 0.1551 | |
| SRP159526 | HYKK | 123688 | RNAseq | 0.0799 | 0.7594 | |
| SRP193095 | HYKK | 123688 | RNAseq | -0.4635 | 0.0001 | |
| SRP219564 | HYKK | 123688 | RNAseq | -0.5568 | 0.3492 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HYKK expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of HYKK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HYKK | 123688 | 7 | 1 | 22 | |
| GSE20123 | HYKK | 123688 | 7 | 1 | 22 | |
| GSE43470 | HYKK | 123688 | 4 | 5 | 34 | |
| GSE46452 | HYKK | 123688 | 3 | 7 | 49 | |
| GSE47630 | HYKK | 123688 | 8 | 10 | 22 | |
| GSE54993 | HYKK | 123688 | 5 | 6 | 59 | |
| GSE54994 | HYKK | 123688 | 5 | 6 | 42 | |
| GSE60625 | HYKK | 123688 | 4 | 0 | 7 | |
| GSE74703 | HYKK | 123688 | 4 | 3 | 29 | |
| GSE74704 | HYKK | 123688 | 3 | 1 | 16 | |
| TCGA | HYKK | 123688 | 14 | 15 | 67 |
Total number of gains: 64; Total number of losses: 55; Total Number of normals: 369.
Somatic mutations of HYKK:
Generating mutation plots.
Highly correlated genes for HYKK:
Showing top 20/240 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HYKK | RAB11B-AS1 | 0.73562 | 3 | 0 | 3 |
| HYKK | SAMD5 | 0.665905 | 3 | 0 | 3 |
| HYKK | GYS2 | 0.665815 | 3 | 0 | 3 |
| HYKK | ULK3 | 0.653021 | 3 | 0 | 3 |
| HYKK | RAB9A | 0.652242 | 3 | 0 | 3 |
| HYKK | STRADB | 0.645866 | 3 | 0 | 3 |
| HYKK | CLDN8 | 0.633833 | 3 | 0 | 3 |
| HYKK | IL18 | 0.632751 | 3 | 0 | 3 |
| HYKK | ACADL | 0.63096 | 4 | 0 | 4 |
| HYKK | CRISP2 | 0.62591 | 3 | 0 | 3 |
| HYKK | WT1-AS | 0.625268 | 3 | 0 | 3 |
| HYKK | ANXA11 | 0.624289 | 4 | 0 | 4 |
| HYKK | DOCK9 | 0.623693 | 3 | 0 | 3 |
| HYKK | B3GALT4 | 0.623563 | 3 | 0 | 3 |
| HYKK | PAIP2B | 0.620909 | 6 | 0 | 5 |
| HYKK | GMDS | 0.619983 | 3 | 0 | 3 |
| HYKK | SLC46A2 | 0.619685 | 3 | 0 | 3 |
| HYKK | SUOX | 0.618282 | 5 | 0 | 4 |
| HYKK | MTERF2 | 0.616761 | 3 | 0 | 3 |
| HYKK | EPB41L3 | 0.615722 | 3 | 0 | 3 |
For details and further investigation, click here
