| Full name: poly(A) binding protein interacting protein 2B | Alias Symbol: KIAA1155 | ||
| Type: protein-coding gene | Cytoband: 2p13.3 | ||
| Entrez ID: 400961 | HGNC ID: HGNC:29200 | Ensembl Gene: ENSG00000124374 | OMIM ID: 611018 |
| Drug and gene relationship at DGIdb | |||
Expression of PAIP2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAIP2B | 400961 | 221868_at | -0.6442 | 0.1786 | |
| GSE20347 | PAIP2B | 400961 | 221868_at | -1.8482 | 0.0000 | |
| GSE23400 | PAIP2B | 400961 | 221868_at | -0.6566 | 0.0000 | |
| GSE26886 | PAIP2B | 400961 | 221868_at | -2.2416 | 0.0000 | |
| GSE29001 | PAIP2B | 400961 | 221868_at | -1.4218 | 0.0002 | |
| GSE38129 | PAIP2B | 400961 | 221868_at | -1.6899 | 0.0000 | |
| GSE45670 | PAIP2B | 400961 | 221868_at | -0.7921 | 0.0019 | |
| GSE53622 | PAIP2B | 400961 | 54321 | -1.9699 | 0.0000 | |
| GSE53624 | PAIP2B | 400961 | 54321 | -1.9830 | 0.0000 | |
| GSE63941 | PAIP2B | 400961 | 221868_at | 1.6565 | 0.0133 | |
| GSE77861 | PAIP2B | 400961 | 221868_at | -0.9884 | 0.0005 | |
| GSE97050 | PAIP2B | 400961 | A_24_P860797 | -1.3264 | 0.0555 | |
| SRP007169 | PAIP2B | 400961 | RNAseq | -3.3347 | 0.0000 | |
| SRP008496 | PAIP2B | 400961 | RNAseq | -2.5812 | 0.0000 | |
| SRP064894 | PAIP2B | 400961 | RNAseq | -1.8960 | 0.0000 | |
| SRP133303 | PAIP2B | 400961 | RNAseq | -1.6835 | 0.0000 | |
| SRP159526 | PAIP2B | 400961 | RNAseq | -1.1827 | 0.0000 | |
| SRP193095 | PAIP2B | 400961 | RNAseq | -2.1073 | 0.0000 | |
| SRP219564 | PAIP2B | 400961 | RNAseq | -1.6021 | 0.0051 | |
| TCGA | PAIP2B | 400961 | RNAseq | -0.7970 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 13.
Survival by PAIP2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAIP2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAIP2B | 400961 | 11 | 1 | 18 | |
| GSE20123 | PAIP2B | 400961 | 11 | 1 | 18 | |
| GSE43470 | PAIP2B | 400961 | 3 | 0 | 40 | |
| GSE46452 | PAIP2B | 400961 | 2 | 3 | 54 | |
| GSE47630 | PAIP2B | 400961 | 7 | 0 | 33 | |
| GSE54993 | PAIP2B | 400961 | 0 | 6 | 64 | |
| GSE54994 | PAIP2B | 400961 | 11 | 0 | 42 | |
| GSE60625 | PAIP2B | 400961 | 0 | 3 | 8 | |
| GSE74703 | PAIP2B | 400961 | 3 | 0 | 33 | |
| GSE74704 | PAIP2B | 400961 | 9 | 0 | 11 | |
| TCGA | PAIP2B | 400961 | 37 | 2 | 57 |
Total number of gains: 94; Total number of losses: 16; Total Number of normals: 378.
Somatic mutations of PAIP2B:
Generating mutation plots.
Highly correlated genes for PAIP2B:
Showing top 20/1511 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAIP2B | SH3BGRL2 | 0.841247 | 7 | 0 | 7 |
| PAIP2B | PAQR8 | 0.835696 | 7 | 0 | 7 |
| PAIP2B | GPD1L | 0.832977 | 11 | 0 | 11 |
| PAIP2B | RBM20 | 0.817436 | 4 | 0 | 4 |
| PAIP2B | HPGD | 0.816968 | 11 | 0 | 11 |
| PAIP2B | SORT1 | 0.816119 | 11 | 0 | 11 |
| PAIP2B | FCHO2 | 0.80504 | 7 | 0 | 7 |
| PAIP2B | SHROOM3 | 0.802812 | 7 | 0 | 7 |
| PAIP2B | FCER1A | 0.792861 | 10 | 0 | 10 |
| PAIP2B | CGNL1 | 0.792055 | 7 | 0 | 7 |
| PAIP2B | TMEM218 | 0.788089 | 3 | 0 | 3 |
| PAIP2B | EPHX2 | 0.786116 | 10 | 0 | 10 |
| PAIP2B | SNORA68 | 0.784758 | 4 | 0 | 4 |
| PAIP2B | GBP6 | 0.784311 | 4 | 0 | 4 |
| PAIP2B | VSIG2 | 0.783459 | 6 | 0 | 6 |
| PAIP2B | CPEB3 | 0.781726 | 11 | 0 | 11 |
| PAIP2B | GALNT12 | 0.780957 | 11 | 0 | 11 |
| PAIP2B | RMND5B | 0.780805 | 12 | 0 | 11 |
| PAIP2B | CA13 | 0.78007 | 3 | 0 | 3 |
| PAIP2B | SUMF1 | 0.774049 | 3 | 0 | 3 |
For details and further investigation, click here
