| Full name: cysteine rich secretory protein 2 | Alias Symbol: CRISP-2|CT36 | ||
| Type: protein-coding gene | Cytoband: 6p12.3 | ||
| Entrez ID: 7180 | HGNC ID: HGNC:12024 | Ensembl Gene: ENSG00000124490 | OMIM ID: 187430 |
| Drug and gene relationship at DGIdb | |||
Expression of CRISP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRISP2 | 7180 | 210262_at | -1.0689 | 0.1858 | |
| GSE20347 | CRISP2 | 7180 | 210262_at | -0.8542 | 0.0000 | |
| GSE23400 | CRISP2 | 7180 | 210262_at | -0.5748 | 0.0000 | |
| GSE26886 | CRISP2 | 7180 | 210262_at | -1.6245 | 0.0013 | |
| GSE29001 | CRISP2 | 7180 | 210262_at | -2.4517 | 0.0000 | |
| GSE38129 | CRISP2 | 7180 | 210262_at | -0.7458 | 0.0000 | |
| GSE45670 | CRISP2 | 7180 | 210262_at | -1.6848 | 0.0017 | |
| GSE53622 | CRISP2 | 7180 | 103949 | -6.3022 | 0.0000 | |
| GSE53624 | CRISP2 | 7180 | 103949 | -6.7032 | 0.0000 | |
| GSE63941 | CRISP2 | 7180 | 210262_at | 0.1255 | 0.3224 | |
| GSE77861 | CRISP2 | 7180 | 210262_at | -0.7129 | 0.0429 | |
| GSE97050 | CRISP2 | 7180 | A_32_P173662 | -3.8195 | 0.1024 | |
| SRP064894 | CRISP2 | 7180 | RNAseq | -6.9295 | 0.0000 | |
| SRP133303 | CRISP2 | 7180 | RNAseq | -3.9440 | 0.0000 | |
| TCGA | CRISP2 | 7180 | RNAseq | 2.1794 | 0.1937 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by CRISP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRISP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRISP2 | 7180 | 5 | 2 | 23 | |
| GSE20123 | CRISP2 | 7180 | 5 | 2 | 23 | |
| GSE43470 | CRISP2 | 7180 | 5 | 0 | 38 | |
| GSE46452 | CRISP2 | 7180 | 2 | 10 | 47 | |
| GSE47630 | CRISP2 | 7180 | 7 | 5 | 28 | |
| GSE54993 | CRISP2 | 7180 | 3 | 1 | 66 | |
| GSE54994 | CRISP2 | 7180 | 8 | 4 | 41 | |
| GSE60625 | CRISP2 | 7180 | 0 | 3 | 8 | |
| GSE74703 | CRISP2 | 7180 | 5 | 0 | 31 | |
| GSE74704 | CRISP2 | 7180 | 2 | 1 | 17 | |
| TCGA | CRISP2 | 7180 | 21 | 12 | 63 |
Total number of gains: 63; Total number of losses: 40; Total Number of normals: 385.
Somatic mutations of CRISP2:
Generating mutation plots.
Highly correlated genes for CRISP2:
Showing top 20/1339 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRISP2 | GYS2 | 0.832239 | 10 | 0 | 10 |
| CRISP2 | CRISP3 | 0.807744 | 11 | 0 | 11 |
| CRISP2 | NCCRP1 | 0.80274 | 3 | 0 | 3 |
| CRISP2 | SLC46A2 | 0.80123 | 6 | 0 | 6 |
| CRISP2 | IL12A-AS1 | 0.792869 | 6 | 0 | 5 |
| CRISP2 | ATG9B | 0.792234 | 7 | 0 | 7 |
| CRISP2 | KRT78 | 0.791695 | 7 | 0 | 7 |
| CRISP2 | FAM3D | 0.783236 | 7 | 0 | 7 |
| CRISP2 | PAQR8 | 0.780707 | 7 | 0 | 7 |
| CRISP2 | UBL3 | 0.776521 | 11 | 0 | 11 |
| CRISP2 | ZNF365 | 0.771186 | 10 | 0 | 10 |
| CRISP2 | NCR1 | 0.768729 | 3 | 0 | 3 |
| CRISP2 | LINC00320 | 0.768277 | 3 | 0 | 3 |
| CRISP2 | SFTA2 | 0.763398 | 4 | 0 | 4 |
| CRISP2 | CCDC160 | 0.76335 | 4 | 0 | 4 |
| CRISP2 | SCNN1B | 0.761658 | 11 | 0 | 11 |
| CRISP2 | FLG | 0.761558 | 11 | 0 | 11 |
| CRISP2 | ZNF503-AS1 | 0.760752 | 6 | 0 | 6 |
| CRISP2 | UPK3B | 0.760387 | 3 | 0 | 3 |
| CRISP2 | HCG22 | 0.758706 | 7 | 0 | 6 |
For details and further investigation, click here
