| Full name: STE20 related adaptor beta | Alias Symbol: CALS-21|PAPK|ILPIPA|ILPIP | ||
| Type: protein-coding gene | Cytoband: 2q33.1 | ||
| Entrez ID: 55437 | HGNC ID: HGNC:13205 | Ensembl Gene: ENSG00000082146 | OMIM ID: 607333 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
STRADB involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04150 | mTOR signaling pathway | |
| hsa04152 | AMPK signaling pathway |
Expression of STRADB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STRADB | 55437 | 223266_at | -0.5254 | 0.2496 | |
| GSE26886 | STRADB | 55437 | 223266_at | -2.2367 | 0.0000 | |
| GSE45670 | STRADB | 55437 | 223266_at | -1.1734 | 0.0004 | |
| GSE53622 | STRADB | 55437 | 17593 | -1.3081 | 0.0000 | |
| GSE53624 | STRADB | 55437 | 17593 | -2.0158 | 0.0000 | |
| GSE63941 | STRADB | 55437 | 223266_at | -1.3094 | 0.0326 | |
| GSE77861 | STRADB | 55437 | 223266_at | -1.5933 | 0.0008 | |
| GSE97050 | STRADB | 55437 | A_23_P90679 | -0.5710 | 0.1986 | |
| SRP007169 | STRADB | 55437 | RNAseq | -3.6017 | 0.0000 | |
| SRP008496 | STRADB | 55437 | RNAseq | -3.2052 | 0.0000 | |
| SRP064894 | STRADB | 55437 | RNAseq | -2.1769 | 0.0000 | |
| SRP133303 | STRADB | 55437 | RNAseq | -1.4058 | 0.0000 | |
| SRP159526 | STRADB | 55437 | RNAseq | -1.1752 | 0.0000 | |
| SRP193095 | STRADB | 55437 | RNAseq | -1.8571 | 0.0000 | |
| SRP219564 | STRADB | 55437 | RNAseq | -1.3556 | 0.0298 | |
| TCGA | STRADB | 55437 | RNAseq | -0.1180 | 0.1915 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by STRADB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STRADB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STRADB | 55437 | 5 | 4 | 21 | |
| GSE20123 | STRADB | 55437 | 5 | 4 | 21 | |
| GSE43470 | STRADB | 55437 | 1 | 1 | 41 | |
| GSE46452 | STRADB | 55437 | 1 | 4 | 54 | |
| GSE47630 | STRADB | 55437 | 4 | 5 | 31 | |
| GSE54993 | STRADB | 55437 | 0 | 3 | 67 | |
| GSE54994 | STRADB | 55437 | 10 | 8 | 35 | |
| GSE60625 | STRADB | 55437 | 0 | 3 | 8 | |
| GSE74703 | STRADB | 55437 | 1 | 1 | 34 | |
| GSE74704 | STRADB | 55437 | 2 | 2 | 16 | |
| TCGA | STRADB | 55437 | 19 | 14 | 63 |
Total number of gains: 48; Total number of losses: 49; Total Number of normals: 391.
Somatic mutations of STRADB:
Generating mutation plots.
Highly correlated genes for STRADB:
Showing top 20/1374 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STRADB | GYS2 | 0.863973 | 6 | 0 | 6 |
| STRADB | SFTA2 | 0.827882 | 4 | 0 | 4 |
| STRADB | YOD1 | 0.818486 | 7 | 0 | 7 |
| STRADB | SH3BGRL2 | 0.811408 | 7 | 0 | 7 |
| STRADB | RANBP9 | 0.801976 | 7 | 0 | 7 |
| STRADB | ESPL1 | 0.799038 | 6 | 0 | 6 |
| STRADB | KRT78 | 0.797358 | 7 | 0 | 7 |
| STRADB | NT5C2 | 0.792077 | 7 | 0 | 7 |
| STRADB | ANXA9 | 0.791068 | 7 | 0 | 7 |
| STRADB | TAX1BP1 | 0.790988 | 7 | 0 | 7 |
| STRADB | CAB39L | 0.787989 | 7 | 0 | 7 |
| STRADB | NAGK | 0.786799 | 7 | 0 | 7 |
| STRADB | CCNG2 | 0.786754 | 7 | 0 | 7 |
| STRADB | PAQR8 | 0.786402 | 7 | 0 | 7 |
| STRADB | SLC10A5 | 0.784016 | 3 | 0 | 3 |
| STRADB | ALDH9A1 | 0.783347 | 8 | 0 | 8 |
| STRADB | CA13 | 0.780568 | 3 | 0 | 3 |
| STRADB | TOM1L2 | 0.780265 | 7 | 0 | 7 |
| STRADB | PHACTR2 | 0.779893 | 7 | 0 | 7 |
| STRADB | EHD3 | 0.778463 | 8 | 0 | 8 |
For details and further investigation, click here
