IDO2

 

Full name: indoleamine 2,3-dioxygenase 2 Alias Symbol: 
Type: protein-coding gene Cytoband: 8p11.21
Entrez ID: 169355 HGNC ID: HGNC:27269 Ensembl Gene: ENSG00000188676 OMIM ID: 612129
Drug and gene relationship at DGIdb

 

Expression of IDO2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IDO2 169355 1568638_a_at 0.1661 0.6702
GSE26886 IDO2 169355 1568638_a_at -0.0535 0.6091
GSE45670 IDO2 169355 1568638_a_at 0.0402 0.7421
GSE53622 IDO2 169355 66054 -0.0653 0.7178
GSE53624 IDO2 169355 66054 -0.6565 0.0000
GSE63941 IDO2 169355 1568638_a_at 0.1589 0.2186
GSE77861 IDO2 169355 1568638_a_at -0.1580 0.0282
TCGA IDO2 169355 RNAseq 1.4063 0.0637

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by IDO2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of IDO2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 IDO2 169355 10 4 16
GSE20123 IDO2 169355 10 4 16
GSE43470 IDO2 169355 7 6 30
GSE46452 IDO2 169355 20 5 34
GSE47630 IDO2 169355 22 1 17
GSE54993 IDO2 169355 2 16 52
GSE54994 IDO2 169355 19 8 26
GSE60625 IDO2 169355 3 0 8
GSE74703 IDO2 169355 7 5 24
GSE74704 IDO2 169355 9 1 10
TCGA IDO2 169355 35 23 38

Total number of gains: 144; Total number of losses: 73; Total Number of normals: 271.  

 

Somatic mutations of IDO2:

 

Generating mutation plots.

 

Highly correlated genes for IDO2:

 

Showing all 15 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IDO2S100B0.640728303
IDO2TTTY110.614622303
IDO2TIFAB0.595936303
IDO2CD1B0.592259303
IDO2TCL1A0.582749403
IDO2IL18RAP0.566552403
IDO2SAMHD10.551084403
IDO2LRP1B0.542481303
IDO2BANK10.538582403
IDO2ZAP700.533014605
IDO2GPR1710.530493503
IDO2LGALS20.530084603
IDO2CD960.525026704
IDO2DENND1C0.513113603
IDO2ANKRD550.509259403

For details and further investigation, click here