BANK1

 

Full name: B cell scaffold protein with ankyrin repeats 1 Alias Symbol: BANK|FLJ20706
Type: protein-coding gene Cytoband: 4q24
Entrez ID: 55024 HGNC ID: HGNC:18233 Ensembl Gene: ENSG00000153064 OMIM ID: 610292
Drug and gene relationship at DGIdb

 

Expression of BANK1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BANK1 55024 1558662_s_at -0.2922 0.8468
GSE20347 BANK1 55024 219667_s_at 0.0134 0.9530
GSE23400 BANK1 55024 219667_s_at 0.0118 0.8077
GSE26886 BANK1 55024 222915_s_at -0.0623 0.5277
GSE29001 BANK1 55024 219667_s_at 0.4446 0.2066
GSE38129 BANK1 55024 219667_s_at -0.2902 0.3425
GSE45670 BANK1 55024 219667_s_at -0.1852 0.7804
GSE53622 BANK1 55024 115021 -1.1585 0.0000
GSE53624 BANK1 55024 115021 -1.4240 0.0000
GSE63941 BANK1 55024 1558662_s_at -0.4995 0.1941
GSE77861 BANK1 55024 222915_s_at -0.1049 0.2558
GSE97050 BANK1 55024 A_23_P10232 0.5787 0.3138
SRP133303 BANK1 55024 RNAseq -0.8899 0.0575
SRP159526 BANK1 55024 RNAseq -1.8313 0.0333
SRP193095 BANK1 55024 RNAseq 0.0140 0.9732
SRP219564 BANK1 55024 RNAseq -0.0077 0.9936
TCGA BANK1 55024 RNAseq -0.3228 0.2799

Upregulated datasets: 0; Downregulated datasets: 3.  


 

Survival by BANK1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of BANK1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BANK1 55024 1 12 17
GSE20123 BANK1 55024 1 12 17
GSE43470 BANK1 55024 0 13 30
GSE46452 BANK1 55024 1 36 22
GSE47630 BANK1 55024 0 20 20
GSE54993 BANK1 55024 9 0 61
GSE54994 BANK1 55024 1 11 41
GSE60625 BANK1 55024 0 3 8
GSE74703 BANK1 55024 0 11 25
GSE74704 BANK1 55024 0 6 14
TCGA BANK1 55024 8 40 48

Total number of gains: 21; Total number of losses: 164; Total Number of normals: 303.  


 

Somatic mutations of BANK1:

 

Generating mutation plots.

 

Highly correlated genes for BANK1:

 

Showing top 20/185 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BANK1MS4A10.789627908
BANK1TLR100.77606505
BANK1CD370.750207909
BANK1BTLA0.745457505
BANK1FCRL30.74535707
BANK1GIMAP10.731187303
BANK1LINC012150.726035504
BANK1CD190.722237909
BANK1GAPT0.710289505
BANK1FCAMR0.702071303
BANK1FCRL10.697979505
BANK1PVRIG0.69723504
BANK1CD79A0.695561008
BANK1SPIB0.693863706
BANK1TAGAP0.689174303
BANK1CD280.685119303
BANK1FCRLA0.684019807
BANK1GIMAP80.683776303
BANK1TCL1A0.679544706
BANK1CNR20.675989505

For details and further investigation, click here