| Full name: TIFA inhibitor | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 497189 | HGNC ID: HGNC:34024 | Ensembl Gene: ENSG00000255833 | OMIM ID: 612663 |
| Drug and gene relationship at DGIdb | |||
Expression of TIFAB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TIFAB | 497189 | 236673_at | 0.1551 | 0.3997 | |
| GSE26886 | TIFAB | 497189 | 236673_at | -0.1359 | 0.3383 | |
| GSE45670 | TIFAB | 497189 | 236673_at | 0.0675 | 0.5338 | |
| GSE53622 | TIFAB | 497189 | 111728 | -0.2713 | 0.1897 | |
| GSE53624 | TIFAB | 497189 | 111728 | -0.4506 | 0.0098 | |
| GSE63941 | TIFAB | 497189 | 236673_at | 0.2011 | 0.1333 | |
| GSE77861 | TIFAB | 497189 | 236673_at | 0.0575 | 0.5285 | |
| GSE97050 | TIFAB | 497189 | A_33_P3380383 | 0.1737 | 0.3791 | |
| SRP133303 | TIFAB | 497189 | RNAseq | -1.2943 | 0.0005 | |
| TCGA | TIFAB | 497189 | RNAseq | 0.9862 | 0.0741 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TIFAB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TIFAB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TIFAB | 497189 | 3 | 11 | 16 | |
| GSE20123 | TIFAB | 497189 | 4 | 11 | 15 | |
| GSE43470 | TIFAB | 497189 | 4 | 5 | 34 | |
| GSE46452 | TIFAB | 497189 | 0 | 27 | 32 | |
| GSE47630 | TIFAB | 497189 | 0 | 21 | 19 | |
| GSE54993 | TIFAB | 497189 | 9 | 1 | 60 | |
| GSE54994 | TIFAB | 497189 | 3 | 13 | 37 | |
| GSE60625 | TIFAB | 497189 | 0 | 0 | 11 | |
| GSE74703 | TIFAB | 497189 | 3 | 4 | 29 | |
| GSE74704 | TIFAB | 497189 | 3 | 5 | 12 | |
| TCGA | TIFAB | 497189 | 4 | 36 | 56 |
Total number of gains: 33; Total number of losses: 134; Total Number of normals: 321.
Somatic mutations of TIFAB:
Generating mutation plots.
Highly correlated genes for TIFAB:
Showing top 20/191 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TIFAB | IKZF1 | 0.742964 | 3 | 0 | 3 |
| TIFAB | CD79B | 0.742066 | 3 | 0 | 3 |
| TIFAB | GIMAP1 | 0.730084 | 3 | 0 | 3 |
| TIFAB | KCNA3 | 0.725703 | 3 | 0 | 3 |
| TIFAB | GRAP2 | 0.719246 | 3 | 0 | 3 |
| TIFAB | PWP1 | 0.715832 | 3 | 0 | 3 |
| TIFAB | ACAP1 | 0.714283 | 4 | 0 | 4 |
| TIFAB | CD37 | 0.712932 | 3 | 0 | 3 |
| TIFAB | SENP3 | 0.711006 | 3 | 0 | 3 |
| TIFAB | PSMB10 | 0.710929 | 3 | 0 | 3 |
| TIFAB | RPA1 | 0.705048 | 3 | 0 | 3 |
| TIFAB | CDC25A | 0.70287 | 3 | 0 | 3 |
| TIFAB | LILRB2 | 0.702289 | 4 | 0 | 4 |
| TIFAB | ANP32E | 0.699131 | 3 | 0 | 3 |
| TIFAB | RPL22L1 | 0.699088 | 3 | 0 | 3 |
| TIFAB | SFMBT1 | 0.698919 | 3 | 0 | 3 |
| TIFAB | IRF8 | 0.698367 | 4 | 0 | 3 |
| TIFAB | TFDP2 | 0.698142 | 3 | 0 | 3 |
| TIFAB | SNX20 | 0.696081 | 5 | 0 | 5 |
| TIFAB | TMEM14B | 0.696033 | 3 | 0 | 3 |
For details and further investigation, click here
