| Full name: S100 calcium binding protein B | Alias Symbol: S100beta | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 6285 | HGNC ID: HGNC:10500 | Ensembl Gene: ENSG00000160307 | OMIM ID: 176990 |
| Drug and gene relationship at DGIdb | |||
Expression of S100B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | S100B | 6285 | 209686_at | -0.8427 | 0.3926 | |
| GSE20347 | S100B | 6285 | 209686_at | -0.4845 | 0.0016 | |
| GSE23400 | S100B | 6285 | 209686_at | -0.2829 | 0.0000 | |
| GSE26886 | S100B | 6285 | 209686_at | -1.0660 | 0.0007 | |
| GSE29001 | S100B | 6285 | 209686_at | -0.2869 | 0.2243 | |
| GSE38129 | S100B | 6285 | 209686_at | -1.2436 | 0.0022 | |
| GSE45670 | S100B | 6285 | 209686_at | -1.3390 | 0.0000 | |
| GSE53622 | S100B | 6285 | 14737 | -1.4460 | 0.0000 | |
| GSE53624 | S100B | 6285 | 14737 | -1.6044 | 0.0000 | |
| GSE63941 | S100B | 6285 | 209686_at | -0.1106 | 0.3731 | |
| GSE77861 | S100B | 6285 | 209686_at | -0.3706 | 0.0150 | |
| GSE97050 | S100B | 6285 | A_23_P143526 | -0.7504 | 0.1377 | |
| SRP064894 | S100B | 6285 | RNAseq | -0.2489 | 0.5077 | |
| SRP133303 | S100B | 6285 | RNAseq | -1.0744 | 0.0037 | |
| SRP159526 | S100B | 6285 | RNAseq | -0.7219 | 0.1665 | |
| SRP219564 | S100B | 6285 | RNAseq | -0.2022 | 0.7921 | |
| TCGA | S100B | 6285 | RNAseq | -0.3715 | 0.1135 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by S100B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of S100B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | S100B | 6285 | 3 | 9 | 18 | |
| GSE20123 | S100B | 6285 | 3 | 9 | 18 | |
| GSE43470 | S100B | 6285 | 0 | 14 | 29 | |
| GSE46452 | S100B | 6285 | 1 | 21 | 37 | |
| GSE47630 | S100B | 6285 | 6 | 17 | 17 | |
| GSE54993 | S100B | 6285 | 8 | 1 | 61 | |
| GSE54994 | S100B | 6285 | 5 | 8 | 40 | |
| GSE60625 | S100B | 6285 | 0 | 0 | 11 | |
| GSE74703 | S100B | 6285 | 0 | 10 | 26 | |
| GSE74704 | S100B | 6285 | 1 | 5 | 14 | |
| TCGA | S100B | 6285 | 10 | 37 | 49 |
Total number of gains: 37; Total number of losses: 131; Total Number of normals: 320.
Somatic mutations of S100B:
Generating mutation plots.
Highly correlated genes for S100B:
Showing top 20/1300 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| S100B | CLEC3B | 0.787299 | 3 | 0 | 3 |
| S100B | RAB9B | 0.766531 | 5 | 0 | 5 |
| S100B | TNFSF12 | 0.762499 | 3 | 0 | 3 |
| S100B | BHMT2 | 0.760827 | 8 | 0 | 8 |
| S100B | NEGR1 | 0.760143 | 5 | 0 | 5 |
| S100B | LRRN4CL | 0.758089 | 5 | 0 | 5 |
| S100B | ZBTB10 | 0.756992 | 3 | 0 | 3 |
| S100B | ANGPTL1 | 0.749164 | 5 | 0 | 5 |
| S100B | CASQ2 | 0.748075 | 8 | 0 | 8 |
| S100B | SORCS1 | 0.74589 | 4 | 0 | 4 |
| S100B | PGM5 | 0.745532 | 7 | 0 | 7 |
| S100B | FXYD1 | 0.744636 | 6 | 0 | 6 |
| S100B | EIF4E3 | 0.739606 | 7 | 0 | 7 |
| S100B | MAN1C1 | 0.735602 | 7 | 0 | 6 |
| S100B | GPRASP2 | 0.734502 | 3 | 0 | 3 |
| S100B | RCAN2 | 0.734277 | 8 | 0 | 8 |
| S100B | RNF150 | 0.733087 | 5 | 0 | 5 |
| S100B | MACROD2 | 0.730273 | 4 | 0 | 4 |
| S100B | DPT | 0.72947 | 8 | 0 | 8 |
| S100B | LRRK2 | 0.728441 | 7 | 0 | 7 |
For details and further investigation, click here
