LGALS2

 

Full name: galectin 2 Alias Symbol: HL14
Type: protein-coding gene Cytoband: 22q13.1
Entrez ID: 3957 HGNC ID: HGNC:6562 Ensembl Gene: ENSG00000100079 OMIM ID: 150571
Drug and gene relationship at DGIdb

 

Expression of LGALS2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LGALS2 3957 208450_at -0.3569 0.6662
GSE20347 LGALS2 3957 208450_at -0.2888 0.0289
GSE23400 LGALS2 3957 208450_at -0.1194 0.0691
GSE26886 LGALS2 3957 208450_at -0.4735 0.1595
GSE29001 LGALS2 3957 208450_at -0.3736 0.1240
GSE38129 LGALS2 3957 208450_at -0.1799 0.3375
GSE45670 LGALS2 3957 208450_at -0.3886 0.1002
GSE53622 LGALS2 3957 12519 -0.7929 0.0000
GSE53624 LGALS2 3957 12519 -1.2051 0.0000
GSE63941 LGALS2 3957 208450_at 0.3263 0.0120
GSE77861 LGALS2 3957 208450_at -0.0976 0.5113
GSE97050 LGALS2 3957 A_23_P120902 0.2064 0.6146
SRP064894 LGALS2 3957 RNAseq 0.0789 0.8598
SRP133303 LGALS2 3957 RNAseq -1.0341 0.0001
SRP159526 LGALS2 3957 RNAseq -1.3196 0.1710
SRP193095 LGALS2 3957 RNAseq -0.5410 0.0538
SRP219564 LGALS2 3957 RNAseq -0.2569 0.6735
TCGA LGALS2 3957 RNAseq -0.7579 0.1093

Upregulated datasets: 0; Downregulated datasets: 2.  

 

Survival by LGALS2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LGALS2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LGALS2 3957 6 5 19
GSE20123 LGALS2 3957 6 4 20
GSE43470 LGALS2 3957 4 6 33
GSE46452 LGALS2 3957 32 2 25
GSE47630 LGALS2 3957 9 4 27
GSE54993 LGALS2 3957 3 6 61
GSE54994 LGALS2 3957 9 8 36
GSE60625 LGALS2 3957 5 0 6
GSE74703 LGALS2 3957 4 4 28
GSE74704 LGALS2 3957 3 2 15
TCGA LGALS2 3957 27 15 54

Total number of gains: 108; Total number of losses: 56; Total Number of normals: 324.  

 

Somatic mutations of LGALS2:

 

Generating mutation plots.

 

Highly correlated genes for LGALS2:

 

Showing top 20/302 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LGALS2MPEG10.767666606
LGALS2C16orf540.740651606
LGALS2GIMAP50.740151403
LGALS2P2RY80.739785404
LGALS2GIMAP70.736257706
LGALS2SNX200.726518606
LGALS2ARHGAP150.722277303
LGALS2C1orf1620.718161606
LGALS2TAGAP0.714494505
LGALS2HLA-DOA0.708375505
LGALS2SPOCK20.707722707
LGALS2XPNPEP20.704481404
LGALS2LILRA40.703164303
LGALS2ARHGAP90.686321605
LGALS2RCSD10.684449606
LGALS2GIMAP60.68112908
LGALS2CNTFR0.679948303
LGALS2GNGT20.679617606
LGALS2CD20.6775781008
LGALS2COL4A40.674745403

For details and further investigation, click here