| Full name: G protein-coupled receptor 171 | Alias Symbol: H963 | ||
| Type: protein-coding gene | Cytoband: 3q25.1 | ||
| Entrez ID: 29909 | HGNC ID: HGNC:30057 | Ensembl Gene: ENSG00000174946 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GPR171:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR171 | 29909 | 207651_at | 0.5632 | 0.7321 | |
| GSE20347 | GPR171 | 29909 | 207651_at | -0.4248 | 0.0782 | |
| GSE23400 | GPR171 | 29909 | 207651_at | -0.0753 | 0.1888 | |
| GSE26886 | GPR171 | 29909 | 207651_at | -0.8191 | 0.0885 | |
| GSE29001 | GPR171 | 29909 | 207651_at | -0.4012 | 0.3271 | |
| GSE38129 | GPR171 | 29909 | 207651_at | -0.5478 | 0.0086 | |
| GSE45670 | GPR171 | 29909 | 207651_at | -0.3404 | 0.4197 | |
| GSE53622 | GPR171 | 29909 | 102954 | -0.3661 | 0.0451 | |
| GSE53624 | GPR171 | 29909 | 102954 | -0.8731 | 0.0000 | |
| GSE63941 | GPR171 | 29909 | 207651_at | 0.1539 | 0.2644 | |
| GSE77861 | GPR171 | 29909 | 207651_at | -0.1808 | 0.1541 | |
| GSE97050 | GPR171 | 29909 | A_23_P253317 | 0.3631 | 0.2429 | |
| SRP007169 | GPR171 | 29909 | RNAseq | -1.4974 | 0.0313 | |
| SRP133303 | GPR171 | 29909 | RNAseq | -0.2148 | 0.3713 | |
| SRP159526 | GPR171 | 29909 | RNAseq | -1.0874 | 0.3224 | |
| SRP219564 | GPR171 | 29909 | RNAseq | 0.0323 | 0.9559 | |
| TCGA | GPR171 | 29909 | RNAseq | -0.1571 | 0.6347 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GPR171 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR171:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR171 | 29909 | 20 | 0 | 10 | |
| GSE20123 | GPR171 | 29909 | 20 | 0 | 10 | |
| GSE43470 | GPR171 | 29909 | 23 | 0 | 20 | |
| GSE46452 | GPR171 | 29909 | 18 | 2 | 39 | |
| GSE47630 | GPR171 | 29909 | 19 | 3 | 18 | |
| GSE54993 | GPR171 | 29909 | 1 | 10 | 59 | |
| GSE54994 | GPR171 | 29909 | 37 | 1 | 15 | |
| GSE60625 | GPR171 | 29909 | 0 | 6 | 5 | |
| GSE74703 | GPR171 | 29909 | 20 | 0 | 16 | |
| GSE74704 | GPR171 | 29909 | 13 | 0 | 7 | |
| TCGA | GPR171 | 29909 | 72 | 1 | 23 |
Total number of gains: 243; Total number of losses: 23; Total Number of normals: 222.
Somatic mutations of GPR171:
Generating mutation plots.
Highly correlated genes for GPR171:
Showing top 20/302 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR171 | CCR4 | 0.814031 | 3 | 0 | 3 |
| GPR171 | GIMAP5 | 0.803621 | 3 | 0 | 3 |
| GPR171 | CD2 | 0.803262 | 11 | 0 | 11 |
| GPR171 | CD3D | 0.789144 | 11 | 0 | 11 |
| GPR171 | GPR174 | 0.777624 | 3 | 0 | 3 |
| GPR171 | ITK | 0.767393 | 11 | 0 | 10 |
| GPR171 | TAGAP | 0.765297 | 5 | 0 | 5 |
| GPR171 | PARVG | 0.759847 | 5 | 0 | 5 |
| GPR171 | ARHGAP15 | 0.752883 | 3 | 0 | 3 |
| GPR171 | CD3E | 0.749003 | 8 | 0 | 7 |
| GPR171 | TNFAIP8L2 | 0.747601 | 5 | 0 | 5 |
| GPR171 | GIMAP7 | 0.745806 | 6 | 0 | 6 |
| GPR171 | CD96 | 0.734752 | 11 | 0 | 11 |
| GPR171 | SAMD3 | 0.731789 | 6 | 0 | 6 |
| GPR171 | CD3G | 0.729567 | 8 | 0 | 8 |
| GPR171 | CD48 | 0.726553 | 10 | 0 | 9 |
| GPR171 | C1orf162 | 0.723292 | 6 | 0 | 5 |
| GPR171 | PIK3CG | 0.719916 | 5 | 0 | 5 |
| GPR171 | VASH1 | 0.718665 | 3 | 0 | 3 |
| GPR171 | CD226 | 0.717531 | 8 | 0 | 7 |
For details and further investigation, click here
