| Full name: chromosome 2 open reading frame 50 | Alias Symbol: FLJ25143 | ||
| Type: protein-coding gene | Cytoband: 2p25.1 | ||
| Entrez ID: 130813 | HGNC ID: HGNC:26324 | Ensembl Gene: ENSG00000150873 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C2orf50:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C2orf50 | 130813 | 1563814_at | -0.0857 | 0.7016 | |
| GSE26886 | C2orf50 | 130813 | 1563814_at | 0.1757 | 0.0618 | |
| GSE45670 | C2orf50 | 130813 | 1563814_at | 0.1008 | 0.2725 | |
| GSE53622 | C2orf50 | 130813 | 150962 | 0.1142 | 0.0831 | |
| GSE53624 | C2orf50 | 130813 | 150962 | -0.6080 | 0.0000 | |
| GSE63941 | C2orf50 | 130813 | 1563814_at | -0.0884 | 0.5530 | |
| GSE77861 | C2orf50 | 130813 | 1563814_at | -0.0813 | 0.4834 | |
| GSE97050 | C2orf50 | 130813 | A_33_P3398998 | -0.0945 | 0.6532 | |
| SRP007169 | C2orf50 | 130813 | RNAseq | 0.6902 | 0.3257 | |
| SRP064894 | C2orf50 | 130813 | RNAseq | 0.3395 | 0.1766 | |
| SRP133303 | C2orf50 | 130813 | RNAseq | 0.1072 | 0.3316 | |
| SRP159526 | C2orf50 | 130813 | RNAseq | 0.3588 | 0.2361 | |
| SRP193095 | C2orf50 | 130813 | RNAseq | 0.2063 | 0.1677 | |
| SRP219564 | C2orf50 | 130813 | RNAseq | 0.2160 | 0.5821 | |
| TCGA | C2orf50 | 130813 | RNAseq | -0.8790 | 0.1011 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C2orf50 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C2orf50:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C2orf50 | 130813 | 10 | 2 | 18 | |
| GSE20123 | C2orf50 | 130813 | 10 | 2 | 18 | |
| GSE43470 | C2orf50 | 130813 | 2 | 1 | 40 | |
| GSE46452 | C2orf50 | 130813 | 3 | 4 | 52 | |
| GSE47630 | C2orf50 | 130813 | 7 | 0 | 33 | |
| GSE54993 | C2orf50 | 130813 | 0 | 7 | 63 | |
| GSE54994 | C2orf50 | 130813 | 11 | 0 | 42 | |
| GSE60625 | C2orf50 | 130813 | 0 | 3 | 8 | |
| GSE74703 | C2orf50 | 130813 | 2 | 0 | 34 | |
| GSE74704 | C2orf50 | 130813 | 9 | 1 | 10 | |
| TCGA | C2orf50 | 130813 | 34 | 5 | 57 |
Total number of gains: 88; Total number of losses: 25; Total Number of normals: 375.
Somatic mutations of C2orf50:
Generating mutation plots.
Highly correlated genes for C2orf50:
Showing top 20/214 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C2orf50 | PLA2G2C | 0.765419 | 3 | 0 | 3 |
| C2orf50 | IL1F10 | 0.755565 | 3 | 0 | 3 |
| C2orf50 | STRC | 0.753799 | 3 | 0 | 3 |
| C2orf50 | MYL7 | 0.752939 | 3 | 0 | 3 |
| C2orf50 | FOXE3 | 0.750196 | 3 | 0 | 3 |
| C2orf50 | SUN5 | 0.748199 | 3 | 0 | 3 |
| C2orf50 | GRIK4 | 0.745284 | 3 | 0 | 3 |
| C2orf50 | BTNL2 | 0.733902 | 3 | 0 | 3 |
| C2orf50 | SLC18A3 | 0.731249 | 3 | 0 | 3 |
| C2orf50 | PAX2 | 0.730587 | 3 | 0 | 3 |
| C2orf50 | HCRT | 0.728273 | 3 | 0 | 3 |
| C2orf50 | RSPH4A | 0.728023 | 3 | 0 | 3 |
| C2orf50 | DCDC1 | 0.724009 | 3 | 0 | 3 |
| C2orf50 | TNNI2 | 0.723069 | 3 | 0 | 3 |
| C2orf50 | KRTAP4-8 | 0.715516 | 3 | 0 | 3 |
| C2orf50 | MRGPRE | 0.714635 | 3 | 0 | 3 |
| C2orf50 | TSPAN11 | 0.714497 | 3 | 0 | 3 |
| C2orf50 | CHD5 | 0.701375 | 3 | 0 | 3 |
| C2orf50 | PTAFR | 0.700589 | 3 | 0 | 3 |
| C2orf50 | SPACA3 | 0.698794 | 4 | 0 | 3 |
For details and further investigation, click here
