GREB1L

 

Full name: GREB1 like retinoic acid receptor coactivator Alias Symbol: FLJ13687|C18orf6
Type: protein-coding gene Cytoband: 18q11.1-q11.2
Entrez ID: 80000 HGNC ID: HGNC:31042 Ensembl Gene: ENSG00000141449 OMIM ID: 617782
Drug and gene relationship at DGIdb

 

Expression of GREB1L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GREB1L 80000 220340_at -0.1410 0.6175
GSE20347 GREB1L 80000 220340_at 0.0867 0.3773
GSE23400 GREB1L 80000 220340_at -0.1532 0.0044
GSE26886 GREB1L 80000 220340_at -0.0026 0.9832
GSE29001 GREB1L 80000 220340_at -0.2355 0.2460
GSE38129 GREB1L 80000 220340_at -0.1475 0.1452
GSE45670 GREB1L 80000 233977_at 0.0863 0.4201
GSE53622 GREB1L 80000 160784 0.0660 0.7755
GSE53624 GREB1L 80000 160784 0.7455 0.0000
GSE63941 GREB1L 80000 243907_at 1.1668 0.0699
GSE77861 GREB1L 80000 220340_at -0.2207 0.1652
GSE97050 GREB1L 80000 A_23_P119040 -0.9804 0.1756
SRP007169 GREB1L 80000 RNAseq 4.6566 0.0005
SRP133303 GREB1L 80000 RNAseq -0.0421 0.8721
SRP159526 GREB1L 80000 RNAseq 2.5788 0.0069
SRP193095 GREB1L 80000 RNAseq 0.2436 0.2673
SRP219564 GREB1L 80000 RNAseq 0.4829 0.5176
TCGA GREB1L 80000 RNAseq -0.4724 0.4742

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by GREB1L expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GREB1L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GREB1L 80000 2 5 23
GSE20123 GREB1L 80000 1 5 24
GSE43470 GREB1L 80000 2 1 40
GSE46452 GREB1L 80000 3 22 34
GSE47630 GREB1L 80000 7 17 16
GSE54993 GREB1L 80000 7 1 62
GSE54994 GREB1L 80000 3 12 38
GSE60625 GREB1L 80000 0 4 7
GSE74703 GREB1L 80000 1 1 34
GSE74704 GREB1L 80000 1 4 15
TCGA GREB1L 80000 18 18 60

Total number of gains: 45; Total number of losses: 90; Total Number of normals: 353.  


 

Somatic mutations of GREB1L:

 

Generating mutation plots.

 

Highly correlated genes for GREB1L:

 

Showing top 20/709 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GREB1LARHGEF260.724782303
GREB1LUBQLN30.722773404
GREB1LADRA1A0.714047303
GREB1LSLC2A20.701862303
GREB1LCGA0.696518404
GREB1LGYPB0.691259303
GREB1LCACNA1H0.686308403
GREB1LKHDRBS20.685068404
GREB1LALB0.678539303
GREB1LFCN20.678233403
GREB1LFAM107A0.676667303
GREB1LIL1RAPL10.676661303
GREB1LKCNMB20.674398504
GREB1LLIPC0.672901303
GREB1LBTNL20.670028403
GREB1LIHH0.667551303
GREB1LP2RX20.667108505
GREB1LFLT30.665389303
GREB1LG6PC20.665234505
GREB1LFGF140.665211404

For details and further investigation, click here