| Full name: matrix metallopeptidase 24 | Alias Symbol: MT5-MMP | ||
| Type: protein-coding gene | Cytoband: 20q11.22 | ||
| Entrez ID: 10893 | HGNC ID: HGNC:7172 | Ensembl Gene: ENSG00000125966 | OMIM ID: 604871 |
| Drug and gene relationship at DGIdb | |||
Expression of MMP24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MMP24 | 10893 | 213171_s_at | 0.0034 | 0.9943 | |
| GSE20347 | MMP24 | 10893 | 208387_s_at | -0.0437 | 0.6087 | |
| GSE23400 | MMP24 | 10893 | 208387_s_at | -0.1318 | 0.0000 | |
| GSE26886 | MMP24 | 10893 | 213171_s_at | -0.1553 | 0.2889 | |
| GSE29001 | MMP24 | 10893 | 208387_s_at | -0.0552 | 0.6905 | |
| GSE38129 | MMP24 | 10893 | 213171_s_at | -0.0520 | 0.4573 | |
| GSE45670 | MMP24 | 10893 | 213171_s_at | -0.0547 | 0.6690 | |
| GSE63941 | MMP24 | 10893 | 213171_s_at | 0.2023 | 0.3054 | |
| GSE77861 | MMP24 | 10893 | 213171_s_at | -0.0077 | 0.9558 | |
| GSE97050 | MMP24 | 10893 | A_33_P3398331 | -0.2040 | 0.4794 | |
| SRP133303 | MMP24 | 10893 | RNAseq | -0.2592 | 0.2864 | |
| SRP159526 | MMP24 | 10893 | RNAseq | 0.1948 | 0.6454 | |
| SRP193095 | MMP24 | 10893 | RNAseq | -0.0468 | 0.7944 | |
| SRP219564 | MMP24 | 10893 | RNAseq | -0.3323 | 0.4612 | |
| TCGA | MMP24 | 10893 | RNAseq | -0.3757 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MMP24 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MMP24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MMP24 | 10893 | 16 | 0 | 14 | |
| GSE20123 | MMP24 | 10893 | 16 | 0 | 14 | |
| GSE43470 | MMP24 | 10893 | 13 | 0 | 30 | |
| GSE46452 | MMP24 | 10893 | 29 | 0 | 30 | |
| GSE47630 | MMP24 | 10893 | 25 | 0 | 15 | |
| GSE54993 | MMP24 | 10893 | 0 | 17 | 53 | |
| GSE54994 | MMP24 | 10893 | 25 | 0 | 28 | |
| GSE60625 | MMP24 | 10893 | 0 | 0 | 11 | |
| GSE74703 | MMP24 | 10893 | 11 | 0 | 25 | |
| GSE74704 | MMP24 | 10893 | 11 | 0 | 9 | |
| TCGA | MMP24 | 10893 | 49 | 3 | 44 |
Total number of gains: 195; Total number of losses: 20; Total Number of normals: 273.
Somatic mutations of MMP24:
Generating mutation plots.
Highly correlated genes for MMP24:
Showing top 20/496 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MMP24 | HSPB6 | 0.716185 | 3 | 0 | 3 |
| MMP24 | SSPO | 0.703886 | 3 | 0 | 3 |
| MMP24 | LINC01015 | 0.693847 | 3 | 0 | 3 |
| MMP24 | AMBN | 0.682218 | 5 | 0 | 5 |
| MMP24 | SLC45A2 | 0.676828 | 5 | 0 | 5 |
| MMP24 | GP2 | 0.66076 | 3 | 0 | 3 |
| MMP24 | ICAM5 | 0.652253 | 3 | 0 | 3 |
| MMP24 | SH2B1 | 0.652151 | 3 | 0 | 3 |
| MMP24 | LIPF | 0.651662 | 3 | 0 | 3 |
| MMP24 | DNAJB5 | 0.650565 | 4 | 0 | 3 |
| MMP24 | MED24 | 0.650325 | 3 | 0 | 3 |
| MMP24 | TRABD2A | 0.647796 | 3 | 0 | 3 |
| MMP24 | EPHA3 | 0.64642 | 5 | 0 | 5 |
| MMP24 | DNAH9 | 0.646125 | 5 | 0 | 5 |
| MMP24 | EDA2R | 0.637624 | 7 | 0 | 6 |
| MMP24 | ACVR2B-AS1 | 0.6324 | 3 | 0 | 3 |
| MMP24 | TRPC4 | 0.630846 | 3 | 0 | 3 |
| MMP24 | DIRAS1 | 0.63038 | 3 | 0 | 3 |
| MMP24 | LGI4 | 0.629067 | 3 | 0 | 3 |
| MMP24 | LRP5 | 0.628916 | 3 | 0 | 3 |
For details and further investigation, click here
