| Full name: kelch like family member 41 | Alias Symbol: SARCOSIN|Krp1 | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 10324 | HGNC ID: HGNC:16905 | Ensembl Gene: ENSG00000239474 | OMIM ID: 607701 |
| Drug and gene relationship at DGIdb | |||
Expression of KLHL41:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHL41 | 10324 | 222827_s_at | -0.3383 | 0.4589 | |
| GSE20347 | KLHL41 | 10324 | 219106_s_at | -0.1119 | 0.2154 | |
| GSE23400 | KLHL41 | 10324 | 219106_s_at | -0.1311 | 0.3525 | |
| GSE26886 | KLHL41 | 10324 | 222827_s_at | -0.0396 | 0.7599 | |
| GSE29001 | KLHL41 | 10324 | 219106_s_at | -0.6211 | 0.1095 | |
| GSE38129 | KLHL41 | 10324 | 219106_s_at | -0.7387 | 0.0056 | |
| GSE45670 | KLHL41 | 10324 | 222827_s_at | 0.0254 | 0.8313 | |
| GSE63941 | KLHL41 | 10324 | 222827_s_at | 0.0963 | 0.6178 | |
| GSE77861 | KLHL41 | 10324 | 222827_s_at | 0.1028 | 0.4343 | |
| SRP064894 | KLHL41 | 10324 | RNAseq | -0.7134 | 0.1415 | |
| SRP133303 | KLHL41 | 10324 | RNAseq | -0.8047 | 0.0690 | |
| SRP159526 | KLHL41 | 10324 | RNAseq | 0.2252 | 0.6963 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of KLHL41:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHL41 | 10324 | 8 | 0 | 22 | |
| GSE20123 | KLHL41 | 10324 | 8 | 0 | 22 | |
| GSE43470 | KLHL41 | 10324 | 5 | 1 | 37 | |
| GSE46452 | KLHL41 | 10324 | 1 | 4 | 54 | |
| GSE47630 | KLHL41 | 10324 | 5 | 3 | 32 | |
| GSE54993 | KLHL41 | 10324 | 0 | 5 | 65 | |
| GSE54994 | KLHL41 | 10324 | 11 | 3 | 39 | |
| GSE60625 | KLHL41 | 10324 | 0 | 3 | 8 | |
| GSE74703 | KLHL41 | 10324 | 4 | 1 | 31 | |
| GSE74704 | KLHL41 | 10324 | 5 | 0 | 15 | |
| TCGA | KLHL41 | 10324 | 24 | 10 | 62 |
Total number of gains: 71; Total number of losses: 30; Total Number of normals: 387.
Somatic mutations of KLHL41:
Generating mutation plots.
Highly correlated genes for KLHL41:
Showing top 20/203 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHL41 | POPDC2 | 0.823175 | 3 | 0 | 3 |
| KLHL41 | KL | 0.775323 | 3 | 0 | 3 |
| KLHL41 | MYOT | 0.76709 | 6 | 0 | 6 |
| KLHL41 | ESRRG | 0.765953 | 3 | 0 | 3 |
| KLHL41 | SLIT2 | 0.752181 | 3 | 0 | 3 |
| KLHL41 | CNGA3 | 0.748451 | 3 | 0 | 3 |
| KLHL41 | ANGPT1 | 0.74126 | 3 | 0 | 3 |
| KLHL41 | KCNMB1 | 0.72482 | 5 | 0 | 5 |
| KLHL41 | SMTN | 0.714328 | 3 | 0 | 3 |
| KLHL41 | PLP1 | 0.705031 | 5 | 0 | 4 |
| KLHL41 | CORO2B | 0.704053 | 4 | 0 | 4 |
| KLHL41 | GSTM5 | 0.703968 | 3 | 0 | 3 |
| KLHL41 | TLN1 | 0.69763 | 3 | 0 | 3 |
| KLHL41 | NAALADL1 | 0.697557 | 3 | 0 | 3 |
| KLHL41 | RASL12 | 0.696905 | 4 | 0 | 3 |
| KLHL41 | CKMT2 | 0.69373 | 5 | 0 | 4 |
| KLHL41 | CCDC181 | 0.690792 | 3 | 0 | 3 |
| KLHL41 | CSRP1 | 0.685796 | 4 | 0 | 3 |
| KLHL41 | SPHKAP | 0.681597 | 3 | 0 | 3 |
| KLHL41 | SEMA3E | 0.681342 | 4 | 0 | 3 |
For details and further investigation, click here
