| Full name: zinc finger protein 385D | Alias Symbol: FLJ22419 | ||
| Type: protein-coding gene | Cytoband: 3p24.3 | ||
| Entrez ID: 79750 | HGNC ID: HGNC:26191 | Ensembl Gene: ENSG00000151789 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZNF385D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF385D | 79750 | 230773_at | -0.6663 | 0.4791 | |
| GSE20347 | ZNF385D | 79750 | 220117_at | 0.0025 | 0.9744 | |
| GSE23400 | ZNF385D | 79750 | 220117_at | -0.0854 | 0.0285 | |
| GSE26886 | ZNF385D | 79750 | 230773_at | 0.0996 | 0.4506 | |
| GSE29001 | ZNF385D | 79750 | 220117_at | -0.1091 | 0.3010 | |
| GSE38129 | ZNF385D | 79750 | 220117_at | -0.5461 | 0.0408 | |
| GSE45670 | ZNF385D | 79750 | 220117_at | -1.3002 | 0.0000 | |
| GSE53622 | ZNF385D | 79750 | 22942 | -1.9609 | 0.0000 | |
| GSE53624 | ZNF385D | 79750 | 22942 | -1.3087 | 0.0000 | |
| GSE63941 | ZNF385D | 79750 | 220117_at | 0.0108 | 0.9524 | |
| GSE77861 | ZNF385D | 79750 | 220117_at | -0.0049 | 0.9777 | |
| GSE97050 | ZNF385D | 79750 | A_23_P113748 | -0.5803 | 0.2878 | |
| SRP007169 | ZNF385D | 79750 | RNAseq | 1.7404 | 0.0488 | |
| SRP064894 | ZNF385D | 79750 | RNAseq | 0.2863 | 0.5601 | |
| SRP133303 | ZNF385D | 79750 | RNAseq | -0.7626 | 0.1530 | |
| SRP159526 | ZNF385D | 79750 | RNAseq | -0.8251 | 0.1020 | |
| SRP193095 | ZNF385D | 79750 | RNAseq | 0.1311 | 0.5429 | |
| SRP219564 | ZNF385D | 79750 | RNAseq | 0.1587 | 0.8680 | |
| TCGA | ZNF385D | 79750 | RNAseq | -1.0630 | 0.0163 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by ZNF385D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF385D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF385D | 79750 | 0 | 19 | 11 | |
| GSE20123 | ZNF385D | 79750 | 0 | 19 | 11 | |
| GSE43470 | ZNF385D | 79750 | 0 | 20 | 23 | |
| GSE46452 | ZNF385D | 79750 | 2 | 17 | 40 | |
| GSE47630 | ZNF385D | 79750 | 1 | 24 | 15 | |
| GSE54993 | ZNF385D | 79750 | 6 | 1 | 63 | |
| GSE54994 | ZNF385D | 79750 | 1 | 32 | 20 | |
| GSE60625 | ZNF385D | 79750 | 5 | 0 | 6 | |
| GSE74703 | ZNF385D | 79750 | 0 | 17 | 19 | |
| GSE74704 | ZNF385D | 79750 | 0 | 13 | 7 | |
| TCGA | ZNF385D | 79750 | 1 | 68 | 27 |
Total number of gains: 16; Total number of losses: 230; Total Number of normals: 242.
Somatic mutations of ZNF385D:
Generating mutation plots.
Highly correlated genes for ZNF385D:
Showing top 20/1067 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF385D | ADAMTSL1 | 0.815969 | 5 | 0 | 5 |
| ZNF385D | CYP21A2 | 0.797974 | 3 | 0 | 3 |
| ZNF385D | FIBIN | 0.790338 | 3 | 0 | 3 |
| ZNF385D | GIPC3 | 0.77733 | 3 | 0 | 3 |
| ZNF385D | RASSF3 | 0.771584 | 4 | 0 | 4 |
| ZNF385D | MRVI1 | 0.767768 | 5 | 0 | 5 |
| ZNF385D | COX7A1 | 0.76764 | 7 | 0 | 7 |
| ZNF385D | C1QTNF7 | 0.765793 | 5 | 0 | 5 |
| ZNF385D | MSRB3 | 0.760937 | 5 | 0 | 5 |
| ZNF385D | CFL2 | 0.75886 | 5 | 0 | 5 |
| ZNF385D | SH3BGR | 0.757308 | 7 | 0 | 7 |
| ZNF385D | MAMDC2 | 0.756572 | 5 | 0 | 5 |
| ZNF385D | ZNF582 | 0.746515 | 3 | 0 | 3 |
| ZNF385D | IL17B | 0.745868 | 4 | 0 | 4 |
| ZNF385D | JAM2 | 0.74259 | 8 | 0 | 7 |
| ZNF385D | CCDC69 | 0.742231 | 8 | 0 | 8 |
| ZNF385D | AQP1 | 0.74109 | 8 | 0 | 7 |
| ZNF385D | C3orf70 | 0.740522 | 6 | 0 | 6 |
| ZNF385D | SYNC | 0.740364 | 5 | 0 | 5 |
| ZNF385D | NEGR1 | 0.737875 | 7 | 0 | 6 |
For details and further investigation, click here
