| Full name: interleukin 16 | Alias Symbol: LCF|IL-16|prIL-16|HsT19289|FLJ42735|FLJ16806 | ||
| Type: protein-coding gene | Cytoband: 15q25.1 | ||
| Entrez ID: 3603 | HGNC ID: HGNC:5980 | Ensembl Gene: ENSG00000172349 | OMIM ID: 603035 |
| Drug and gene relationship at DGIdb | |||
Expression of IL16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL16 | 3603 | 209827_s_at | -0.1744 | 0.8797 | |
| GSE20347 | IL16 | 3603 | 209827_s_at | -0.0090 | 0.9533 | |
| GSE23400 | IL16 | 3603 | 209827_s_at | -0.1816 | 0.0003 | |
| GSE26886 | IL16 | 3603 | 209827_s_at | -0.2212 | 0.3259 | |
| GSE29001 | IL16 | 3603 | 209827_s_at | -0.1826 | 0.1367 | |
| GSE38129 | IL16 | 3603 | 209827_s_at | -0.3730 | 0.0361 | |
| GSE45670 | IL16 | 3603 | 209827_s_at | -0.5940 | 0.0067 | |
| GSE53622 | IL16 | 3603 | 49704 | -0.2348 | 0.1347 | |
| GSE53624 | IL16 | 3603 | 18494 | -0.1204 | 0.1268 | |
| GSE63941 | IL16 | 3603 | 209827_s_at | -0.6527 | 0.0010 | |
| GSE77861 | IL16 | 3603 | 1555016_at | -0.0941 | 0.4675 | |
| GSE97050 | IL16 | 3603 | A_33_P3359683 | -0.2871 | 0.3746 | |
| SRP007169 | IL16 | 3603 | RNAseq | 0.9552 | 0.1921 | |
| SRP064894 | IL16 | 3603 | RNAseq | 0.0504 | 0.8514 | |
| SRP133303 | IL16 | 3603 | RNAseq | -0.5996 | 0.0006 | |
| SRP159526 | IL16 | 3603 | RNAseq | -1.1480 | 0.0867 | |
| SRP193095 | IL16 | 3603 | RNAseq | -0.1097 | 0.6538 | |
| SRP219564 | IL16 | 3603 | RNAseq | 0.0826 | 0.8556 | |
| TCGA | IL16 | 3603 | RNAseq | -0.1149 | 0.2897 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IL16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL16 | 3603 | 7 | 1 | 22 | |
| GSE20123 | IL16 | 3603 | 7 | 1 | 22 | |
| GSE43470 | IL16 | 3603 | 4 | 5 | 34 | |
| GSE46452 | IL16 | 3603 | 3 | 7 | 49 | |
| GSE47630 | IL16 | 3603 | 8 | 10 | 22 | |
| GSE54993 | IL16 | 3603 | 5 | 6 | 59 | |
| GSE54994 | IL16 | 3603 | 5 | 7 | 41 | |
| GSE60625 | IL16 | 3603 | 4 | 0 | 7 | |
| GSE74703 | IL16 | 3603 | 4 | 2 | 30 | |
| GSE74704 | IL16 | 3603 | 3 | 1 | 16 | |
| TCGA | IL16 | 3603 | 15 | 14 | 67 |
Total number of gains: 65; Total number of losses: 54; Total Number of normals: 369.
Somatic mutations of IL16:
Generating mutation plots.
Highly correlated genes for IL16:
Showing top 20/259 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL16 | ATP2A3 | 0.725754 | 5 | 0 | 5 |
| IL16 | MS4A1 | 0.681737 | 5 | 0 | 4 |
| IL16 | CD19 | 0.680938 | 5 | 0 | 4 |
| IL16 | RCSD1 | 0.679018 | 4 | 0 | 3 |
| IL16 | LINC01013 | 0.669378 | 3 | 0 | 3 |
| IL16 | KRTAP19-3 | 0.666773 | 3 | 0 | 3 |
| IL16 | LAX1 | 0.665794 | 4 | 0 | 4 |
| IL16 | TESC | 0.657611 | 4 | 0 | 3 |
| IL16 | ANHX | 0.655265 | 3 | 0 | 3 |
| IL16 | INPP5D | 0.654546 | 6 | 0 | 4 |
| IL16 | GTSF1L | 0.652641 | 3 | 0 | 3 |
| IL16 | CYP2A6 | 0.650003 | 3 | 0 | 3 |
| IL16 | PVRIG | 0.649971 | 6 | 0 | 4 |
| IL16 | RHOH | 0.646079 | 7 | 0 | 6 |
| IL16 | RNASE6 | 0.6413 | 4 | 0 | 3 |
| IL16 | TCL6 | 0.634475 | 3 | 0 | 3 |
| IL16 | PNOC | 0.632376 | 5 | 0 | 3 |
| IL16 | IRF8 | 0.625948 | 7 | 0 | 4 |
| IL16 | GIMAP4 | 0.625849 | 6 | 0 | 4 |
| IL16 | GPR18 | 0.624189 | 6 | 0 | 4 |
For details and further investigation, click here
