| Full name: prepronociceptin | Alias Symbol: PPNOC|N/OFQ|NOP | ||
| Type: protein-coding gene | Cytoband: 8p21.1 | ||
| Entrez ID: 5368 | HGNC ID: HGNC:9163 | Ensembl Gene: ENSG00000168081 | OMIM ID: 601459 |
| Drug and gene relationship at DGIdb | |||
Expression of PNOC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PNOC | 5368 | 205901_at | 0.0316 | 0.9633 | |
| GSE20347 | PNOC | 5368 | 205901_at | 0.1065 | 0.1613 | |
| GSE23400 | PNOC | 5368 | 205901_at | -0.0793 | 0.0430 | |
| GSE26886 | PNOC | 5368 | 205901_at | 0.0553 | 0.6295 | |
| GSE29001 | PNOC | 5368 | 205901_at | -0.1241 | 0.5862 | |
| GSE38129 | PNOC | 5368 | 205901_at | -0.0502 | 0.7515 | |
| GSE45670 | PNOC | 5368 | 205901_at | 0.0332 | 0.8907 | |
| GSE53622 | PNOC | 5368 | 34710 | -0.0136 | 0.9485 | |
| GSE53624 | PNOC | 5368 | 34710 | -0.2441 | 0.3137 | |
| GSE63941 | PNOC | 5368 | 205901_at | 0.1444 | 0.3670 | |
| GSE77861 | PNOC | 5368 | 205901_at | 0.0934 | 0.4318 | |
| GSE97050 | PNOC | 5368 | A_23_P253321 | 0.3861 | 0.2163 | |
| TCGA | PNOC | 5368 | RNAseq | -1.1803 | 0.0218 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PNOC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PNOC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PNOC | 5368 | 4 | 10 | 16 | |
| GSE20123 | PNOC | 5368 | 4 | 10 | 16 | |
| GSE43470 | PNOC | 5368 | 4 | 7 | 32 | |
| GSE46452 | PNOC | 5368 | 13 | 13 | 33 | |
| GSE47630 | PNOC | 5368 | 10 | 8 | 22 | |
| GSE54993 | PNOC | 5368 | 2 | 15 | 53 | |
| GSE54994 | PNOC | 5368 | 10 | 15 | 28 | |
| GSE60625 | PNOC | 5368 | 3 | 0 | 8 | |
| GSE74703 | PNOC | 5368 | 4 | 6 | 26 | |
| GSE74704 | PNOC | 5368 | 3 | 7 | 10 | |
| TCGA | PNOC | 5368 | 17 | 43 | 36 |
Total number of gains: 74; Total number of losses: 134; Total Number of normals: 280.
Somatic mutations of PNOC:
Generating mutation plots.
Highly correlated genes for PNOC:
Showing top 20/419 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PNOC | CPNE5 | 0.765884 | 4 | 0 | 4 |
| PNOC | MEI1 | 0.75213 | 3 | 0 | 3 |
| PNOC | FCRL5 | 0.733443 | 5 | 0 | 4 |
| PNOC | CAMK1G | 0.726612 | 3 | 0 | 3 |
| PNOC | FCRLA | 0.722031 | 4 | 0 | 4 |
| PNOC | IGK | 0.711719 | 6 | 0 | 5 |
| PNOC | FCRL3 | 0.709551 | 4 | 0 | 4 |
| PNOC | P2RY8 | 0.707999 | 3 | 0 | 3 |
| PNOC | MS4A1 | 0.707651 | 7 | 0 | 6 |
| PNOC | CD79A | 0.705149 | 8 | 0 | 6 |
| PNOC | CD19 | 0.700245 | 8 | 0 | 7 |
| PNOC | SPIB | 0.682455 | 6 | 0 | 5 |
| PNOC | TCL1A | 0.68238 | 7 | 0 | 6 |
| PNOC | GEMIN7 | 0.681619 | 3 | 0 | 3 |
| PNOC | ASIC4 | 0.680323 | 4 | 0 | 4 |
| PNOC | ABCA4 | 0.678944 | 3 | 0 | 3 |
| PNOC | STAG3 | 0.678138 | 5 | 0 | 4 |
| PNOC | CD27 | 0.675784 | 7 | 0 | 6 |
| PNOC | ZC3H12D | 0.674437 | 3 | 0 | 3 |
| PNOC | FOXN3-AS2 | 0.673635 | 3 | 0 | 3 |
For details and further investigation, click here
