| Full name: ILK associated serine/threonine phosphatase | Alias Symbol: DKFZP434J2031|FLJ10181|PPM1O | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 80895 | HGNC ID: HGNC:15566 | Ensembl Gene: ENSG00000132323 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ILKAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ILKAP | 80895 | 221548_s_at | 0.5240 | 0.6954 | |
| GSE20347 | ILKAP | 80895 | 221548_s_at | 0.0529 | 0.7012 | |
| GSE23400 | ILKAP | 80895 | 221548_s_at | 0.0451 | 0.4891 | |
| GSE26886 | ILKAP | 80895 | 221548_s_at | -0.3991 | 0.0546 | |
| GSE29001 | ILKAP | 80895 | 221548_s_at | 0.0404 | 0.9257 | |
| GSE38129 | ILKAP | 80895 | 221548_s_at | 0.0301 | 0.8418 | |
| GSE45670 | ILKAP | 80895 | 221548_s_at | 0.1288 | 0.2591 | |
| GSE53622 | ILKAP | 80895 | 30580 | 0.1383 | 0.0205 | |
| GSE53624 | ILKAP | 80895 | 30580 | 0.1131 | 0.1652 | |
| GSE63941 | ILKAP | 80895 | 221548_s_at | -0.9873 | 0.0067 | |
| GSE77861 | ILKAP | 80895 | 221548_s_at | 0.3994 | 0.0151 | |
| GSE97050 | ILKAP | 80895 | A_23_P142590 | 0.1380 | 0.6039 | |
| SRP007169 | ILKAP | 80895 | RNAseq | 0.2016 | 0.5709 | |
| SRP008496 | ILKAP | 80895 | RNAseq | 0.1398 | 0.5925 | |
| SRP064894 | ILKAP | 80895 | RNAseq | 0.4214 | 0.0329 | |
| SRP133303 | ILKAP | 80895 | RNAseq | 0.2881 | 0.0785 | |
| SRP159526 | ILKAP | 80895 | RNAseq | 0.3502 | 0.1372 | |
| SRP193095 | ILKAP | 80895 | RNAseq | 0.0942 | 0.3629 | |
| SRP219564 | ILKAP | 80895 | RNAseq | -0.0015 | 0.9960 | |
| TCGA | ILKAP | 80895 | RNAseq | 0.0850 | 0.1567 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ILKAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ILKAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ILKAP | 80895 | 1 | 12 | 17 | |
| GSE20123 | ILKAP | 80895 | 1 | 12 | 17 | |
| GSE43470 | ILKAP | 80895 | 1 | 9 | 33 | |
| GSE46452 | ILKAP | 80895 | 0 | 5 | 54 | |
| GSE47630 | ILKAP | 80895 | 4 | 5 | 31 | |
| GSE54993 | ILKAP | 80895 | 3 | 2 | 65 | |
| GSE54994 | ILKAP | 80895 | 8 | 9 | 36 | |
| GSE60625 | ILKAP | 80895 | 0 | 3 | 8 | |
| GSE74703 | ILKAP | 80895 | 1 | 7 | 28 | |
| GSE74704 | ILKAP | 80895 | 1 | 5 | 14 | |
| TCGA | ILKAP | 80895 | 12 | 27 | 57 |
Total number of gains: 32; Total number of losses: 96; Total Number of normals: 360.
Somatic mutations of ILKAP:
Generating mutation plots.
Highly correlated genes for ILKAP:
Showing top 20/297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ILKAP | TRIM35 | 0.728392 | 4 | 0 | 4 |
| ILKAP | NAPG | 0.724321 | 3 | 0 | 3 |
| ILKAP | SGPP1 | 0.713153 | 3 | 0 | 3 |
| ILKAP | ZBED6 | 0.707978 | 4 | 0 | 4 |
| ILKAP | IL13RA2 | 0.695585 | 4 | 0 | 4 |
| ILKAP | CPT1A | 0.68176 | 3 | 0 | 3 |
| ILKAP | NKIRAS2 | 0.681202 | 3 | 0 | 3 |
| ILKAP | UHRF1BP1L | 0.68003 | 3 | 0 | 3 |
| ILKAP | PKN1 | 0.679332 | 3 | 0 | 3 |
| ILKAP | SPATA9 | 0.670492 | 3 | 0 | 3 |
| ILKAP | MB21D2 | 0.669426 | 4 | 0 | 4 |
| ILKAP | ZDBF2 | 0.669002 | 4 | 0 | 3 |
| ILKAP | SCAF4 | 0.667482 | 3 | 0 | 3 |
| ILKAP | FXR1 | 0.6668 | 3 | 0 | 3 |
| ILKAP | FKBP2 | 0.666371 | 4 | 0 | 3 |
| ILKAP | THAP1 | 0.665073 | 4 | 0 | 4 |
| ILKAP | SNRNP200 | 0.66351 | 4 | 0 | 4 |
| ILKAP | VPS37A | 0.663124 | 3 | 0 | 3 |
| ILKAP | ABHD6 | 0.657591 | 3 | 0 | 3 |
| ILKAP | TGIF1 | 0.657433 | 3 | 0 | 3 |
For details and further investigation, click here
