| Full name: abhydrolase domain containing 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p14.3 | ||
| Entrez ID: 57406 | HGNC ID: HGNC:21398 | Ensembl Gene: ENSG00000163686 | OMIM ID: 616966 |
| Drug and gene relationship at DGIdb | |||
Expression of ABHD6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABHD6 | 57406 | 221552_at | 0.4415 | 0.4812 | |
| GSE20347 | ABHD6 | 57406 | 221552_at | -0.2460 | 0.1053 | |
| GSE23400 | ABHD6 | 57406 | 221552_at | -0.1062 | 0.1284 | |
| GSE26886 | ABHD6 | 57406 | 45288_at | -0.2092 | 0.3768 | |
| GSE29001 | ABHD6 | 57406 | 45288_at | -0.0800 | 0.7190 | |
| GSE38129 | ABHD6 | 57406 | 45288_at | -0.3796 | 0.0037 | |
| GSE45670 | ABHD6 | 57406 | 221552_at | 0.3420 | 0.0866 | |
| GSE53622 | ABHD6 | 57406 | 28789 | -0.5805 | 0.0000 | |
| GSE53624 | ABHD6 | 57406 | 28789 | -0.4931 | 0.0002 | |
| GSE63941 | ABHD6 | 57406 | 221552_at | 0.0024 | 0.9973 | |
| GSE77861 | ABHD6 | 57406 | 221552_at | -0.1634 | 0.3776 | |
| GSE97050 | ABHD6 | 57406 | A_23_P211850 | 0.0142 | 0.9732 | |
| SRP007169 | ABHD6 | 57406 | RNAseq | -0.8510 | 0.0241 | |
| SRP008496 | ABHD6 | 57406 | RNAseq | -0.2331 | 0.4654 | |
| SRP064894 | ABHD6 | 57406 | RNAseq | -0.0065 | 0.9663 | |
| SRP133303 | ABHD6 | 57406 | RNAseq | -0.1993 | 0.4101 | |
| SRP159526 | ABHD6 | 57406 | RNAseq | 0.1540 | 0.7377 | |
| SRP193095 | ABHD6 | 57406 | RNAseq | -0.7215 | 0.0000 | |
| SRP219564 | ABHD6 | 57406 | RNAseq | -0.7954 | 0.0498 | |
| TCGA | ABHD6 | 57406 | RNAseq | -0.3400 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ABHD6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABHD6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABHD6 | 57406 | 0 | 17 | 13 | |
| GSE20123 | ABHD6 | 57406 | 0 | 18 | 12 | |
| GSE43470 | ABHD6 | 57406 | 0 | 17 | 26 | |
| GSE46452 | ABHD6 | 57406 | 2 | 17 | 40 | |
| GSE47630 | ABHD6 | 57406 | 1 | 24 | 15 | |
| GSE54993 | ABHD6 | 57406 | 6 | 2 | 62 | |
| GSE54994 | ABHD6 | 57406 | 0 | 32 | 21 | |
| GSE60625 | ABHD6 | 57406 | 5 | 0 | 6 | |
| GSE74703 | ABHD6 | 57406 | 0 | 14 | 22 | |
| GSE74704 | ABHD6 | 57406 | 0 | 11 | 9 | |
| TCGA | ABHD6 | 57406 | 0 | 79 | 17 |
Total number of gains: 14; Total number of losses: 231; Total Number of normals: 243.
Somatic mutations of ABHD6:
Generating mutation plots.
Highly correlated genes for ABHD6:
Showing top 20/82 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABHD6 | B3GNT2 | 0.753396 | 3 | 0 | 3 |
| ABHD6 | NGF | 0.746898 | 3 | 0 | 3 |
| ABHD6 | CASP9 | 0.746122 | 3 | 0 | 3 |
| ABHD6 | PTPN12 | 0.742195 | 3 | 0 | 3 |
| ABHD6 | PLA2G4A | 0.707327 | 3 | 0 | 3 |
| ABHD6 | ENOSF1 | 0.698971 | 3 | 0 | 3 |
| ABHD6 | FITM2 | 0.68965 | 3 | 0 | 3 |
| ABHD6 | LINGO1 | 0.68 | 3 | 0 | 3 |
| ABHD6 | CYP26B1 | 0.679218 | 3 | 0 | 3 |
| ABHD6 | ARL5B | 0.67572 | 3 | 0 | 3 |
| ABHD6 | TMEM129 | 0.674481 | 3 | 0 | 3 |
| ABHD6 | TGFB2 | 0.669409 | 3 | 0 | 3 |
| ABHD6 | FOXQ1 | 0.668524 | 3 | 0 | 3 |
| ABHD6 | TUBG1 | 0.665276 | 3 | 0 | 3 |
| ABHD6 | ILKAP | 0.657591 | 3 | 0 | 3 |
| ABHD6 | SLC6A2 | 0.656002 | 3 | 0 | 3 |
| ABHD6 | BTBD7 | 0.652522 | 3 | 0 | 3 |
| ABHD6 | TMEM184B | 0.650712 | 3 | 0 | 3 |
| ABHD6 | GLRX2 | 0.646549 | 5 | 0 | 4 |
| ABHD6 | ALAS1 | 0.636181 | 5 | 0 | 3 |
For details and further investigation, click here
