SNRNP200

 

Full name: small nuclear ribonucleoprotein U5 subunit 200 Alias Symbol: U5-200KD|HELIC2|KIAA0788|BRR2
Type: protein-coding gene Cytoband: 2q11.2
Entrez ID: 23020 HGNC ID: HGNC:30859 Ensembl Gene: ENSG00000144028 OMIM ID: 601664
Drug and gene relationship at DGIdb

 

Expression of SNRNP200:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SNRNP200 23020 232931_at 0.2153 0.8049
GSE26886 SNRNP200 23020 232931_at -0.6869 0.0012
GSE45670 SNRNP200 23020 232931_at 0.2702 0.0628
GSE53622 SNRNP200 23020 96340 0.4194 0.0000
GSE53624 SNRNP200 23020 96340 0.5016 0.0000
GSE63941 SNRNP200 23020 232931_at 0.0445 0.9069
GSE77861 SNRNP200 23020 232931_at 0.0929 0.3809
GSE97050 SNRNP200 23020 A_23_P131626 0.0672 0.7529
SRP007169 SNRNP200 23020 RNAseq 2.0861 0.0000
SRP008496 SNRNP200 23020 RNAseq 1.9997 0.0000
SRP064894 SNRNP200 23020 RNAseq 0.4386 0.0216
SRP133303 SNRNP200 23020 RNAseq 0.3500 0.0017
SRP159526 SNRNP200 23020 RNAseq 0.5413 0.0424
SRP193095 SNRNP200 23020 RNAseq 0.3204 0.0001
SRP219564 SNRNP200 23020 RNAseq 0.4198 0.2743
TCGA SNRNP200 23020 RNAseq 0.0462 0.2385

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by SNRNP200 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SNRNP200:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SNRNP200 23020 6 2 22
GSE20123 SNRNP200 23020 6 2 22
GSE43470 SNRNP200 23020 2 3 38
GSE46452 SNRNP200 23020 2 3 54
GSE47630 SNRNP200 23020 7 0 33
GSE54993 SNRNP200 23020 0 6 64
GSE54994 SNRNP200 23020 11 0 42
GSE60625 SNRNP200 23020 0 3 8
GSE74703 SNRNP200 23020 2 2 32
GSE74704 SNRNP200 23020 4 1 15
TCGA SNRNP200 23020 36 3 57

Total number of gains: 76; Total number of losses: 25; Total Number of normals: 387.  


 

Somatic mutations of SNRNP200:

 

Generating mutation plots.

 

Highly correlated genes for SNRNP200:

 

Showing top 20/358 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SNRNP200UBXN2A0.83557303
SNRNP200KHNYN0.809294303
SNRNP200TBRG10.797253303
SNRNP200NEDD80.790418303
SNRNP200ANKHD10.773548303
SNRNP200METTL170.769544303
SNRNP200DDX590.764094303
SNRNP200SLC35E10.761007303
SNRNP200NKTR0.758257303
SNRNP200BRCA10.756783303
SNRNP200CBFA2T20.749542303
SNRNP200MZT10.748299404
SNRNP200CRK0.746338303
SNRNP200C6orf1630.745477303
SNRNP200EPRS0.740715303
SNRNP200TMEM2370.738504303
SNRNP200KIN0.737384303
SNRNP200STON20.735688303
SNRNP200TTC40.731023303
SNRNP200USP140.731021303

For details and further investigation, click here