| Full name: protein phosphatase 1 regulatory subunit 13B | Alias Symbol: p53BP2-like|KIAA0771|p85|ASPP1 | ||
| Type: protein-coding gene | Cytoband: 14q32.33 | ||
| Entrez ID: 23368 | HGNC ID: HGNC:14950 | Ensembl Gene: ENSG00000088808 | OMIM ID: 606455 |
| Drug and gene relationship at DGIdb | |||
Expression of PPP1R13B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP1R13B | 23368 | 216347_s_at | -0.1074 | 0.8647 | |
| GSE20347 | PPP1R13B | 23368 | 216347_s_at | -0.3574 | 0.0702 | |
| GSE23400 | PPP1R13B | 23368 | 216347_s_at | -0.2206 | 0.0071 | |
| GSE26886 | PPP1R13B | 23368 | 216347_s_at | 0.3118 | 0.1338 | |
| GSE29001 | PPP1R13B | 23368 | 216347_s_at | -0.3236 | 0.3104 | |
| GSE38129 | PPP1R13B | 23368 | 216347_s_at | -0.2900 | 0.0655 | |
| GSE45670 | PPP1R13B | 23368 | 216347_s_at | 0.0972 | 0.5849 | |
| GSE53622 | PPP1R13B | 23368 | 60835 | -0.5094 | 0.0000 | |
| GSE53624 | PPP1R13B | 23368 | 60835 | -0.4867 | 0.0000 | |
| GSE63941 | PPP1R13B | 23368 | 216347_s_at | 1.5414 | 0.0057 | |
| GSE77861 | PPP1R13B | 23368 | 216347_s_at | -0.1410 | 0.5464 | |
| GSE97050 | PPP1R13B | 23368 | A_33_P3365134 | -0.0385 | 0.8637 | |
| SRP007169 | PPP1R13B | 23368 | RNAseq | -0.2178 | 0.5506 | |
| SRP008496 | PPP1R13B | 23368 | RNAseq | -0.2373 | 0.5035 | |
| SRP064894 | PPP1R13B | 23368 | RNAseq | -0.5894 | 0.0021 | |
| SRP133303 | PPP1R13B | 23368 | RNAseq | -0.3577 | 0.0106 | |
| SRP159526 | PPP1R13B | 23368 | RNAseq | -0.2539 | 0.3832 | |
| SRP193095 | PPP1R13B | 23368 | RNAseq | -0.2172 | 0.1346 | |
| SRP219564 | PPP1R13B | 23368 | RNAseq | -0.5916 | 0.0616 | |
| TCGA | PPP1R13B | 23368 | RNAseq | -0.1261 | 0.0330 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PPP1R13B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP1R13B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP1R13B | 23368 | 12 | 3 | 15 | |
| GSE20123 | PPP1R13B | 23368 | 11 | 2 | 17 | |
| GSE43470 | PPP1R13B | 23368 | 6 | 4 | 33 | |
| GSE46452 | PPP1R13B | 23368 | 19 | 4 | 36 | |
| GSE47630 | PPP1R13B | 23368 | 10 | 8 | 22 | |
| GSE54993 | PPP1R13B | 23368 | 3 | 8 | 59 | |
| GSE54994 | PPP1R13B | 23368 | 22 | 4 | 27 | |
| GSE60625 | PPP1R13B | 23368 | 0 | 2 | 9 | |
| GSE74703 | PPP1R13B | 23368 | 5 | 3 | 28 | |
| GSE74704 | PPP1R13B | 23368 | 5 | 2 | 13 | |
| TCGA | PPP1R13B | 23368 | 30 | 21 | 45 |
Total number of gains: 123; Total number of losses: 61; Total Number of normals: 304.
Somatic mutations of PPP1R13B:
Generating mutation plots.
Highly correlated genes for PPP1R13B:
Showing top 20/184 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP1R13B | IPO13 | 0.811476 | 3 | 0 | 3 |
| PPP1R13B | EGR4 | 0.794054 | 3 | 0 | 3 |
| PPP1R13B | STK11 | 0.769423 | 3 | 0 | 3 |
| PPP1R13B | RTEL1 | 0.741884 | 3 | 0 | 3 |
| PPP1R13B | OR3A3 | 0.73831 | 4 | 0 | 3 |
| PPP1R13B | MAT1A | 0.734978 | 4 | 0 | 4 |
| PPP1R13B | OR10C1 | 0.733769 | 4 | 0 | 4 |
| PPP1R13B | PTAFR | 0.710827 | 3 | 0 | 3 |
| PPP1R13B | WDR90 | 0.707043 | 3 | 0 | 3 |
| PPP1R13B | DOHH | 0.703136 | 4 | 0 | 4 |
| PPP1R13B | C11orf86 | 0.693605 | 3 | 0 | 3 |
| PPP1R13B | SHC2 | 0.692426 | 4 | 0 | 3 |
| PPP1R13B | LIM2 | 0.67924 | 3 | 0 | 3 |
| PPP1R13B | PARP10 | 0.674591 | 3 | 0 | 3 |
| PPP1R13B | SDR42E1 | 0.674567 | 3 | 0 | 3 |
| PPP1R13B | HAUS5 | 0.674275 | 3 | 0 | 3 |
| PPP1R13B | MYO15B | 0.670151 | 4 | 0 | 3 |
| PPP1R13B | MAPK8IP2 | 0.659962 | 4 | 0 | 3 |
| PPP1R13B | EFNA4 | 0.643156 | 4 | 0 | 3 |
| PPP1R13B | ZNF205 | 0.642432 | 5 | 0 | 4 |
For details and further investigation, click here
