| Full name: LHFPL tetraspan subfamily member 5 | Alias Symbol: MGC33835|dJ510O8.8|Tmhs | ||
| Type: protein-coding gene | Cytoband: 6p21.31 | ||
| Entrez ID: 222662 | HGNC ID: HGNC:21253 | Ensembl Gene: ENSG00000197753 | OMIM ID: 609427 |
| Drug and gene relationship at DGIdb | |||
Expression of LHFPL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LHFPL5 | 222662 | 1555043_at | 0.1028 | 0.6623 | |
| GSE26886 | LHFPL5 | 222662 | 1555043_at | -0.1141 | 0.3598 | |
| GSE45670 | LHFPL5 | 222662 | 1555043_at | 0.1171 | 0.2669 | |
| GSE53622 | LHFPL5 | 222662 | 72271 | 0.1972 | 0.0068 | |
| GSE53624 | LHFPL5 | 222662 | 72271 | -0.0991 | 0.2697 | |
| GSE63941 | LHFPL5 | 222662 | 1555043_at | 0.2396 | 0.1491 | |
| GSE77861 | LHFPL5 | 222662 | 1555043_at | -0.0375 | 0.7097 | |
| GSE97050 | LHFPL5 | 222662 | A_32_P494620 | 0.4007 | 0.2101 | |
| SRP064894 | LHFPL5 | 222662 | RNAseq | -0.1338 | 0.6226 | |
| SRP133303 | LHFPL5 | 222662 | RNAseq | 0.2533 | 0.1889 | |
| SRP159526 | LHFPL5 | 222662 | RNAseq | -0.1539 | 0.6154 | |
| SRP193095 | LHFPL5 | 222662 | RNAseq | -0.0930 | 0.4302 | |
| SRP219564 | LHFPL5 | 222662 | RNAseq | 0.4365 | 0.4206 | |
| TCGA | LHFPL5 | 222662 | RNAseq | 0.9851 | 0.2114 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LHFPL5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LHFPL5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LHFPL5 | 222662 | 5 | 0 | 25 | |
| GSE20123 | LHFPL5 | 222662 | 5 | 0 | 25 | |
| GSE43470 | LHFPL5 | 222662 | 5 | 1 | 37 | |
| GSE46452 | LHFPL5 | 222662 | 2 | 9 | 48 | |
| GSE47630 | LHFPL5 | 222662 | 8 | 4 | 28 | |
| GSE54993 | LHFPL5 | 222662 | 3 | 1 | 66 | |
| GSE54994 | LHFPL5 | 222662 | 11 | 4 | 38 | |
| GSE60625 | LHFPL5 | 222662 | 1 | 0 | 10 | |
| GSE74703 | LHFPL5 | 222662 | 5 | 0 | 31 | |
| GSE74704 | LHFPL5 | 222662 | 2 | 0 | 18 | |
| TCGA | LHFPL5 | 222662 | 15 | 15 | 66 |
Total number of gains: 62; Total number of losses: 34; Total Number of normals: 392.
Somatic mutations of LHFPL5:
Generating mutation plots.
Highly correlated genes for LHFPL5:
Showing top 20/113 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LHFPL5 | OR10H1 | 0.78121 | 3 | 0 | 3 |
| LHFPL5 | SLC12A3 | 0.774312 | 3 | 0 | 3 |
| LHFPL5 | IL21 | 0.759546 | 3 | 0 | 3 |
| LHFPL5 | PTCRA | 0.744319 | 3 | 0 | 3 |
| LHFPL5 | KCNA6 | 0.720952 | 3 | 0 | 3 |
| LHFPL5 | ABCC8 | 0.703796 | 3 | 0 | 3 |
| LHFPL5 | MMP17 | 0.701529 | 3 | 0 | 3 |
| LHFPL5 | PIP5KL1 | 0.70023 | 4 | 0 | 3 |
| LHFPL5 | IPO13 | 0.698367 | 3 | 0 | 3 |
| LHFPL5 | CES3 | 0.694123 | 3 | 0 | 3 |
| LHFPL5 | SEC14L4 | 0.691872 | 3 | 0 | 3 |
| LHFPL5 | B3GALT1 | 0.69083 | 3 | 0 | 3 |
| LHFPL5 | CRYBB3 | 0.68524 | 3 | 0 | 3 |
| LHFPL5 | IL9R | 0.678387 | 3 | 0 | 3 |
| LHFPL5 | SLC25A48 | 0.671386 | 4 | 0 | 4 |
| LHFPL5 | SLC4A1 | 0.657581 | 4 | 0 | 3 |
| LHFPL5 | HAGHL | 0.652706 | 3 | 0 | 3 |
| LHFPL5 | DLK1 | 0.652481 | 4 | 0 | 4 |
| LHFPL5 | KIF21B | 0.648215 | 4 | 0 | 3 |
| LHFPL5 | MYBPH | 0.646526 | 4 | 0 | 3 |
For details and further investigation, click here
