PLA2G4F

 

Full name: phospholipase A2 group IVF Alias Symbol: PLA2G4F/Z
Type: protein-coding gene Cytoband: 15q15.1
Entrez ID: 255189 HGNC ID: HGNC:27396 Ensembl Gene: ENSG00000168907 OMIM ID: 
Drug and gene relationship at DGIdb

 

PLA2G4F involved pathways:

KEGG pathway Description View
hsa04010MAPK signaling pathway
hsa04014Ras signaling pathway
hsa04270Vascular smooth muscle contraction
hsa04370VEGF signaling pathway
hsa04611Platelet activation
hsa04664Fc epsilon RI signaling pathway
hsa04666Fc gamma R-mediated phagocytosis
hsa04724Glutamatergic synapse
hsa04726Serotonergic synapse
hsa04730Long-term depression
hsa04750Inflammatory mediator regulation of TRP channels
hsa04912GnRH signaling pathway
hsa04913Ovarian steroidogenesis
hsa04921Oxytocin signaling pathway
hsa05231Choline metabolism in cancer

 

Expression of PLA2G4F:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PLA2G4F 255189 235958_at -0.1383 0.7018
GSE26886 PLA2G4F 255189 235958_at -0.1908 0.3063
GSE45670 PLA2G4F 255189 235958_at 0.1314 0.2972
GSE53622 PLA2G4F 255189 18196 -0.4163 0.0040
GSE53624 PLA2G4F 255189 115711 -0.2663 0.0135
GSE63941 PLA2G4F 255189 235958_at 0.4355 0.0252
GSE77861 PLA2G4F 255189 235958_at 0.0373 0.8667
GSE97050 PLA2G4F 255189 A_24_P147169 -0.1048 0.7835
SRP007169 PLA2G4F 255189 RNAseq -1.1505 0.1172
SRP008496 PLA2G4F 255189 RNAseq -1.5055 0.0006
SRP064894 PLA2G4F 255189 RNAseq -1.8821 0.0000
SRP133303 PLA2G4F 255189 RNAseq -0.6548 0.0367
SRP159526 PLA2G4F 255189 RNAseq -0.2533 0.8070
SRP193095 PLA2G4F 255189 RNAseq -0.7706 0.0011
SRP219564 PLA2G4F 255189 RNAseq -0.7162 0.5928
TCGA PLA2G4F 255189 RNAseq -0.1408 0.7008

Upregulated datasets: 0; Downregulated datasets: 2.  

 

Survival by PLA2G4F expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PLA2G4F:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PLA2G4F 255189 4 5 21
GSE20123 PLA2G4F 255189 4 6 20
GSE43470 PLA2G4F 255189 4 5 34
GSE46452 PLA2G4F 255189 3 7 49
GSE47630 PLA2G4F 255189 8 11 21
GSE54993 PLA2G4F 255189 4 6 60
GSE54994 PLA2G4F 255189 5 7 41
GSE60625 PLA2G4F 255189 4 0 7
GSE74703 PLA2G4F 255189 4 4 28
GSE74704 PLA2G4F 255189 3 3 14
TCGA PLA2G4F 255189 11 17 68

Total number of gains: 54; Total number of losses: 71; Total Number of normals: 363.  

 

Somatic mutations of PLA2G4F:

 

Generating mutation plots.

 

Highly correlated genes for PLA2G4F:

 

Showing top 20/373 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PLA2G4FRAD520.751776303
PLA2G4FC11orf860.750853303
PLA2G4FSLC25A480.737866303
PLA2G4FPHGR10.732457303
PLA2G4FMYO15B0.719582303
PLA2G4FRUFY40.714642303
PLA2G4FGRAP0.705087404
PLA2G4FFGF180.701457303
PLA2G4FCEACAM10.697975303
PLA2G4FEME20.691383303
PLA2G4FSLC35C10.686602303
PLA2G4FEGR40.685717303
PLA2G4FHCRT0.685311404
PLA2G4FNKAIN40.684441303
PLA2G4FABCC80.684392303
PLA2G4FIGFN10.682514303
PLA2G4FPOR0.676924303
PLA2G4FADRA2C0.676495303
PLA2G4FPGAM20.675883303
PLA2G4FGPR390.675297303

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