| Full name: N-acetyltransferase 14 (putative) | Alias Symbol: KLP1 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 57106 | HGNC ID: HGNC:28918 | Ensembl Gene: ENSG00000090971 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NAT14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAT14 | 57106 | 223284_at | 1.0100 | 0.0494 | |
| GSE26886 | NAT14 | 57106 | 223284_at | 1.6000 | 0.0000 | |
| GSE45670 | NAT14 | 57106 | 223284_at | 0.5152 | 0.0106 | |
| GSE53622 | NAT14 | 57106 | 91024 | 0.9909 | 0.0000 | |
| GSE53624 | NAT14 | 57106 | 91024 | 1.3245 | 0.0000 | |
| GSE63941 | NAT14 | 57106 | 223284_at | -1.0026 | 0.0523 | |
| GSE77861 | NAT14 | 57106 | 223284_at | 0.3002 | 0.1067 | |
| GSE97050 | NAT14 | 57106 | A_23_P50389 | 0.3373 | 0.2944 | |
| SRP007169 | NAT14 | 57106 | RNAseq | 2.8408 | 0.0001 | |
| SRP008496 | NAT14 | 57106 | RNAseq | 3.2700 | 0.0000 | |
| SRP064894 | NAT14 | 57106 | RNAseq | 2.2874 | 0.0000 | |
| SRP133303 | NAT14 | 57106 | RNAseq | 0.7267 | 0.0055 | |
| SRP159526 | NAT14 | 57106 | RNAseq | 2.0333 | 0.0005 | |
| SRP219564 | NAT14 | 57106 | RNAseq | 1.0276 | 0.0956 | |
| TCGA | NAT14 | 57106 | RNAseq | 0.4423 | 0.0002 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by NAT14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAT14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAT14 | 57106 | 3 | 4 | 23 | |
| GSE20123 | NAT14 | 57106 | 3 | 3 | 24 | |
| GSE43470 | NAT14 | 57106 | 3 | 10 | 30 | |
| GSE46452 | NAT14 | 57106 | 45 | 1 | 13 | |
| GSE47630 | NAT14 | 57106 | 8 | 6 | 26 | |
| GSE54993 | NAT14 | 57106 | 17 | 4 | 49 | |
| GSE54994 | NAT14 | 57106 | 4 | 13 | 36 | |
| GSE60625 | NAT14 | 57106 | 9 | 0 | 2 | |
| GSE74703 | NAT14 | 57106 | 3 | 6 | 27 | |
| GSE74704 | NAT14 | 57106 | 3 | 1 | 16 | |
| TCGA | NAT14 | 57106 | 19 | 14 | 63 |
Total number of gains: 117; Total number of losses: 62; Total Number of normals: 309.
Somatic mutations of NAT14:
Generating mutation plots.
Highly correlated genes for NAT14:
Showing top 20/529 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAT14 | TNFAIP8L1 | 0.770023 | 4 | 0 | 4 |
| NAT14 | MFAP2 | 0.76929 | 6 | 0 | 5 |
| NAT14 | BMF | 0.754505 | 5 | 0 | 4 |
| NAT14 | LONP1 | 0.74408 | 7 | 0 | 6 |
| NAT14 | SHISA8 | 0.743713 | 3 | 0 | 3 |
| NAT14 | C19orf53 | 0.741961 | 4 | 0 | 4 |
| NAT14 | HSD17B14 | 0.741229 | 3 | 0 | 3 |
| NAT14 | TMEM9 | 0.740142 | 7 | 0 | 7 |
| NAT14 | DBF4B | 0.73096 | 4 | 0 | 4 |
| NAT14 | GSDMD | 0.72858 | 6 | 0 | 5 |
| NAT14 | CHGB | 0.725709 | 4 | 0 | 3 |
| NAT14 | LAMA5 | 0.723361 | 3 | 0 | 3 |
| NAT14 | FZD9 | 0.723218 | 3 | 0 | 3 |
| NAT14 | HOXC9 | 0.722178 | 5 | 0 | 4 |
| NAT14 | PAX6 | 0.719839 | 4 | 0 | 3 |
| NAT14 | ASMTL | 0.717918 | 4 | 0 | 4 |
| NAT14 | RFX8 | 0.713091 | 3 | 0 | 3 |
| NAT14 | CLCNKB | 0.7129 | 3 | 0 | 3 |
| NAT14 | IQCH | 0.710929 | 4 | 0 | 4 |
| NAT14 | LBX2-AS1 | 0.707863 | 4 | 0 | 4 |
For details and further investigation, click here
