| Full name: leucine rich repeat and fibronectin type III domain containing 3 | Alias Symbol: MGC2656|SALM4|FIGLER1 | ||
| Type: protein-coding gene | Cytoband: 19q13.13 | ||
| Entrez ID: 79414 | HGNC ID: HGNC:28370 | Ensembl Gene: ENSG00000126243 | OMIM ID: 612809 |
| Drug and gene relationship at DGIdb | |||
Expression of LRFN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRFN3 | 79414 | 219346_at | 0.2130 | 0.4616 | |
| GSE20347 | LRFN3 | 79414 | 219346_at | -0.2792 | 0.1798 | |
| GSE23400 | LRFN3 | 79414 | 219346_at | -0.0387 | 0.4050 | |
| GSE26886 | LRFN3 | 79414 | 219346_at | 1.1321 | 0.0000 | |
| GSE29001 | LRFN3 | 79414 | 219346_at | 0.0253 | 0.9434 | |
| GSE38129 | LRFN3 | 79414 | 219346_at | -0.0553 | 0.7555 | |
| GSE45670 | LRFN3 | 79414 | 219346_at | 0.0414 | 0.8023 | |
| GSE53622 | LRFN3 | 79414 | 62387 | 0.0003 | 0.9955 | |
| GSE53624 | LRFN3 | 79414 | 62387 | 0.2947 | 0.0002 | |
| GSE63941 | LRFN3 | 79414 | 219346_at | -0.2703 | 0.6214 | |
| GSE77861 | LRFN3 | 79414 | 219346_at | -0.2110 | 0.1297 | |
| GSE97050 | LRFN3 | 79414 | A_23_P50775 | 0.1509 | 0.4427 | |
| SRP007169 | LRFN3 | 79414 | RNAseq | 0.7848 | 0.2417 | |
| SRP008496 | LRFN3 | 79414 | RNAseq | 0.3482 | 0.4560 | |
| SRP064894 | LRFN3 | 79414 | RNAseq | 1.1288 | 0.0000 | |
| SRP133303 | LRFN3 | 79414 | RNAseq | 0.0076 | 0.9751 | |
| SRP159526 | LRFN3 | 79414 | RNAseq | 0.8850 | 0.0024 | |
| SRP193095 | LRFN3 | 79414 | RNAseq | 0.2716 | 0.0607 | |
| SRP219564 | LRFN3 | 79414 | RNAseq | 0.2919 | 0.3438 | |
| TCGA | LRFN3 | 79414 | RNAseq | 0.1066 | 0.1707 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by LRFN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRFN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRFN3 | 79414 | 7 | 4 | 19 | |
| GSE20123 | LRFN3 | 79414 | 7 | 3 | 20 | |
| GSE43470 | LRFN3 | 79414 | 3 | 7 | 33 | |
| GSE46452 | LRFN3 | 79414 | 48 | 1 | 10 | |
| GSE47630 | LRFN3 | 79414 | 9 | 5 | 26 | |
| GSE54993 | LRFN3 | 79414 | 17 | 3 | 50 | |
| GSE54994 | LRFN3 | 79414 | 6 | 9 | 38 | |
| GSE60625 | LRFN3 | 79414 | 9 | 0 | 2 | |
| GSE74703 | LRFN3 | 79414 | 3 | 4 | 29 | |
| GSE74704 | LRFN3 | 79414 | 6 | 1 | 13 | |
| TCGA | LRFN3 | 79414 | 22 | 10 | 64 |
Total number of gains: 137; Total number of losses: 47; Total Number of normals: 304.
Somatic mutations of LRFN3:
Generating mutation plots.
Highly correlated genes for LRFN3:
Showing top 20/153 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRFN3 | CPAMD8 | 0.83016 | 3 | 0 | 3 |
| LRFN3 | TTC7A | 0.821585 | 3 | 0 | 3 |
| LRFN3 | AMPD2 | 0.807452 | 3 | 0 | 3 |
| LRFN3 | THAP3 | 0.792463 | 3 | 0 | 3 |
| LRFN3 | MGAT5B | 0.784463 | 3 | 0 | 3 |
| LRFN3 | RPP25 | 0.770184 | 3 | 0 | 3 |
| LRFN3 | BMF | 0.746366 | 3 | 0 | 3 |
| LRFN3 | TNIP2 | 0.734551 | 3 | 0 | 3 |
| LRFN3 | ARHGAP30 | 0.726246 | 3 | 0 | 3 |
| LRFN3 | PARP10 | 0.722235 | 3 | 0 | 3 |
| LRFN3 | CLCN1 | 0.704944 | 3 | 0 | 3 |
| LRFN3 | SYT3 | 0.70487 | 3 | 0 | 3 |
| LRFN3 | CPNE9 | 0.69907 | 4 | 0 | 3 |
| LRFN3 | PTPRN2 | 0.690917 | 3 | 0 | 3 |
| LRFN3 | RASGRF2 | 0.687795 | 3 | 0 | 3 |
| LRFN3 | KAT2A | 0.687673 | 4 | 0 | 3 |
| LRFN3 | RTEL1 | 0.684512 | 4 | 0 | 3 |
| LRFN3 | PTPRCAP | 0.68338 | 3 | 0 | 3 |
| LRFN3 | FBLN7 | 0.681652 | 3 | 0 | 3 |
| LRFN3 | ZIC1 | 0.678505 | 3 | 0 | 3 |
For details and further investigation, click here
