| Full name: NADPH oxidase 5 | Alias Symbol: NOX5A|NOX5B | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 79400 | HGNC ID: HGNC:14874 | Ensembl Gene: ENSG00000255346 | OMIM ID: 606572 |
| Drug and gene relationship at DGIdb | |||
Expression of NOX5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOX5 | 79400 | 220641_at | -0.1296 | 0.6076 | |
| GSE20347 | NOX5 | 79400 | 220641_at | -0.1123 | 0.2009 | |
| GSE23400 | NOX5 | 79400 | 220641_at | -0.1398 | 0.0028 | |
| GSE26886 | NOX5 | 79400 | 220641_at | 0.1379 | 0.3509 | |
| GSE29001 | NOX5 | 79400 | 220641_at | -0.3715 | 0.0544 | |
| GSE38129 | NOX5 | 79400 | 220641_at | -0.1806 | 0.1369 | |
| GSE45670 | NOX5 | 79400 | 220641_at | 0.0605 | 0.6704 | |
| GSE53622 | NOX5 | 79400 | 116773 | -0.5050 | 0.0041 | |
| GSE53624 | NOX5 | 79400 | 50218 | -1.1131 | 0.0000 | |
| GSE63941 | NOX5 | 79400 | 220641_at | 0.4312 | 0.0040 | |
| GSE77861 | NOX5 | 79400 | 220641_at | -0.0769 | 0.6489 | |
| GSE97050 | NOX5 | 79400 | A_23_P140475 | 0.0941 | 0.6269 | |
| SRP064894 | NOX5 | 79400 | RNAseq | -0.7207 | 0.1002 | |
| SRP133303 | NOX5 | 79400 | RNAseq | -0.2117 | 0.7214 | |
| SRP159526 | NOX5 | 79400 | RNAseq | -2.0968 | 0.0017 | |
| TCGA | NOX5 | 79400 | RNAseq | 0.1456 | 0.7994 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NOX5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOX5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOX5 | 79400 | 7 | 1 | 22 | |
| GSE20123 | NOX5 | 79400 | 7 | 1 | 22 | |
| GSE43470 | NOX5 | 79400 | 4 | 6 | 33 | |
| GSE46452 | NOX5 | 79400 | 3 | 7 | 49 | |
| GSE47630 | NOX5 | 79400 | 8 | 10 | 22 | |
| GSE54993 | NOX5 | 79400 | 5 | 6 | 59 | |
| GSE54994 | NOX5 | 79400 | 5 | 7 | 41 | |
| GSE60625 | NOX5 | 79400 | 4 | 0 | 7 | |
| GSE74703 | NOX5 | 79400 | 4 | 3 | 29 | |
| GSE74704 | NOX5 | 79400 | 3 | 1 | 16 | |
| TCGA | NOX5 | 79400 | 10 | 15 | 71 |
Total number of gains: 60; Total number of losses: 57; Total Number of normals: 371.
Somatic mutations of NOX5:
Generating mutation plots.
Highly correlated genes for NOX5:
Showing top 20/825 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOX5 | C11orf16 | 0.722932 | 6 | 0 | 6 |
| NOX5 | AMN | 0.700583 | 6 | 0 | 6 |
| NOX5 | CNGB3 | 0.699802 | 5 | 0 | 5 |
| NOX5 | SGK2 | 0.69219 | 3 | 0 | 3 |
| NOX5 | HABP2 | 0.688556 | 4 | 0 | 4 |
| NOX5 | FGF4 | 0.688528 | 3 | 0 | 3 |
| NOX5 | IQSEC2 | 0.68213 | 4 | 0 | 4 |
| NOX5 | C6 | 0.681641 | 3 | 0 | 3 |
| NOX5 | PRB4 | 0.681301 | 5 | 0 | 4 |
| NOX5 | GDF3 | 0.67184 | 5 | 0 | 4 |
| NOX5 | TNK1 | 0.670271 | 4 | 0 | 4 |
| NOX5 | TAAR2 | 0.669351 | 4 | 0 | 4 |
| NOX5 | NOS1 | 0.663574 | 5 | 0 | 5 |
| NOX5 | FAM223B | 0.663023 | 3 | 0 | 3 |
| NOX5 | ABCB9 | 0.66293 | 4 | 0 | 4 |
| NOX5 | GLP1R | 0.66126 | 7 | 0 | 5 |
| NOX5 | GDF2 | 0.660922 | 7 | 0 | 6 |
| NOX5 | MYOG | 0.660872 | 9 | 0 | 6 |
| NOX5 | CGA | 0.660735 | 4 | 0 | 4 |
| NOX5 | EXTL1 | 0.660634 | 4 | 0 | 4 |
For details and further investigation, click here
