| Full name: Ras converting CAAX endopeptidase 1 | Alias Symbol: hRCE1|FACE-2|FACE2 | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 9986 | HGNC ID: HGNC:13721 | Ensembl Gene: ENSG00000173653 | OMIM ID: 605385 |
Expression of RCE1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RCE1 | 9986 | 205333_s_at | 0.4627 | 0.3387 | |
| GSE20347 | RCE1 | 9986 | 205333_s_at | 0.2708 | 0.0108 | |
| GSE23400 | RCE1 | 9986 | 205333_s_at | 0.3240 | 0.0000 | |
| GSE26886 | RCE1 | 9986 | 205333_s_at | 0.4315 | 0.0230 | |
| GSE29001 | RCE1 | 9986 | 205333_s_at | -0.0698 | 0.7391 | |
| GSE38129 | RCE1 | 9986 | 205333_s_at | 0.3737 | 0.0010 | |
| GSE45670 | RCE1 | 9986 | 205333_s_at | 0.1255 | 0.3422 | |
| GSE63941 | RCE1 | 9986 | 205333_s_at | 1.3398 | 0.0006 | |
| GSE77861 | RCE1 | 9986 | 205332_at | -0.1123 | 0.2679 | |
| GSE97050 | RCE1 | 9986 | A_23_P1641 | 0.3965 | 0.2082 | |
| SRP007169 | RCE1 | 9986 | RNAseq | -0.1127 | 0.7653 | |
| SRP008496 | RCE1 | 9986 | RNAseq | 0.1979 | 0.5154 | |
| SRP064894 | RCE1 | 9986 | RNAseq | 0.4336 | 0.0293 | |
| SRP133303 | RCE1 | 9986 | RNAseq | 0.8286 | 0.0000 | |
| SRP159526 | RCE1 | 9986 | RNAseq | 0.4917 | 0.0711 | |
| SRP193095 | RCE1 | 9986 | RNAseq | 0.4030 | 0.0017 | |
| SRP219564 | RCE1 | 9986 | RNAseq | 0.3750 | 0.3051 | |
| TCGA | RCE1 | 9986 | RNAseq | 0.2644 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RCE1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RCE1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RCE1 | 9986 | 9 | 3 | 18 | |
| GSE20123 | RCE1 | 9986 | 9 | 3 | 18 | |
| GSE43470 | RCE1 | 9986 | 6 | 1 | 36 | |
| GSE46452 | RCE1 | 9986 | 12 | 3 | 44 | |
| GSE47630 | RCE1 | 9986 | 9 | 4 | 27 | |
| GSE54993 | RCE1 | 9986 | 3 | 0 | 67 | |
| GSE54994 | RCE1 | 9986 | 10 | 7 | 36 | |
| GSE60625 | RCE1 | 9986 | 0 | 3 | 8 | |
| GSE74703 | RCE1 | 9986 | 4 | 0 | 32 | |
| GSE74704 | RCE1 | 9986 | 7 | 1 | 12 | |
| TCGA | RCE1 | 9986 | 24 | 9 | 63 |
Total number of gains: 93; Total number of losses: 34; Total Number of normals: 361.
Somatic mutations of RCE1:
Generating mutation plots.
Highly correlated genes for RCE1:
Showing top 20/301 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RCE1 | BIN3 | 0.699178 | 3 | 0 | 3 |
| RCE1 | C10orf55 | 0.697245 | 3 | 0 | 3 |
| RCE1 | HLA-DOB | 0.686921 | 3 | 0 | 3 |
| RCE1 | IQSEC2 | 0.685333 | 3 | 0 | 3 |
| RCE1 | FANCD2 | 0.683993 | 3 | 0 | 3 |
| RCE1 | STARD10 | 0.677175 | 4 | 0 | 3 |
| RCE1 | LINC00698 | 0.676743 | 3 | 0 | 3 |
| RCE1 | RAB1B | 0.675172 | 4 | 0 | 4 |
| RCE1 | MYBPC3 | 0.674501 | 3 | 0 | 3 |
| RCE1 | HOXB6 | 0.648338 | 3 | 0 | 3 |
| RCE1 | POLR2E | 0.646817 | 3 | 0 | 3 |
| RCE1 | ZSWIM1 | 0.646511 | 4 | 0 | 3 |
| RCE1 | SORD | 0.645051 | 5 | 0 | 4 |
| RCE1 | REEP4 | 0.644991 | 5 | 0 | 5 |
| RCE1 | DEPDC5 | 0.64085 | 3 | 0 | 3 |
| RCE1 | INO80B | 0.640217 | 7 | 0 | 5 |
| RCE1 | XPO6 | 0.639202 | 4 | 0 | 3 |
| RCE1 | PPP1CA | 0.638972 | 8 | 0 | 7 |
| RCE1 | MTFP1 | 0.634619 | 4 | 0 | 3 |
| RCE1 | TMEM222 | 0.632045 | 3 | 0 | 3 |
For details and further investigation, click here
