| Full name: double C2 domain beta | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 8447 | HGNC ID: HGNC:2986 | Ensembl Gene: ENSG00000272636 | OMIM ID: 604568 |
| Drug and gene relationship at DGIdb | |||
Expression of DOC2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DOC2B | 8447 | 207311_at | 0.0560 | 0.8426 | |
| GSE20347 | DOC2B | 8447 | 207311_at | -0.0389 | 0.6903 | |
| GSE23400 | DOC2B | 8447 | 207311_at | -0.1818 | 0.0001 | |
| GSE26886 | DOC2B | 8447 | 207311_at | 0.2486 | 0.1049 | |
| GSE29001 | DOC2B | 8447 | 207311_at | -0.1435 | 0.4677 | |
| GSE38129 | DOC2B | 8447 | 207311_at | -0.1462 | 0.0609 | |
| GSE45670 | DOC2B | 8447 | 207311_at | 0.1792 | 0.0447 | |
| GSE53622 | DOC2B | 8447 | 93376 | -0.3437 | 0.1056 | |
| GSE53624 | DOC2B | 8447 | 93376 | -0.2515 | 0.1097 | |
| GSE63941 | DOC2B | 8447 | 207311_at | 0.5135 | 0.0003 | |
| GSE77861 | DOC2B | 8447 | 207311_at | -0.0394 | 0.7187 | |
| GSE97050 | DOC2B | 8447 | A_24_P236753 | 0.7992 | 0.1163 | |
| TCGA | DOC2B | 8447 | RNAseq | 0.0033 | 0.9898 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DOC2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DOC2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DOC2B | 8447 | 4 | 4 | 22 | |
| GSE20123 | DOC2B | 8447 | 4 | 5 | 21 | |
| GSE43470 | DOC2B | 8447 | 1 | 7 | 35 | |
| GSE46452 | DOC2B | 8447 | 34 | 1 | 24 | |
| GSE47630 | DOC2B | 8447 | 8 | 1 | 31 | |
| GSE54993 | DOC2B | 8447 | 8 | 3 | 59 | |
| GSE54994 | DOC2B | 8447 | 7 | 9 | 37 | |
| GSE60625 | DOC2B | 8447 | 4 | 0 | 7 | |
| GSE74703 | DOC2B | 8447 | 1 | 4 | 31 | |
| GSE74704 | DOC2B | 8447 | 2 | 2 | 16 | |
| TCGA | DOC2B | 8447 | 19 | 21 | 56 |
Total number of gains: 92; Total number of losses: 57; Total Number of normals: 339.
Somatic mutations of DOC2B:
Generating mutation plots.
Highly correlated genes for DOC2B:
Showing top 20/873 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DOC2B | PI15 | 0.817951 | 3 | 0 | 3 |
| DOC2B | GGT5 | 0.734221 | 5 | 0 | 5 |
| DOC2B | ADCYAP1 | 0.734173 | 4 | 0 | 4 |
| DOC2B | CRYBB2 | 0.72868 | 3 | 0 | 3 |
| DOC2B | CENPH | 0.727274 | 3 | 0 | 3 |
| DOC2B | PLEK | 0.726026 | 3 | 0 | 3 |
| DOC2B | SSNA1 | 0.725413 | 3 | 0 | 3 |
| DOC2B | GTPBP2 | 0.716572 | 4 | 0 | 4 |
| DOC2B | CHCHD5 | 0.705112 | 3 | 0 | 3 |
| DOC2B | GPR132 | 0.701997 | 5 | 0 | 5 |
| DOC2B | SARDH | 0.695873 | 6 | 0 | 5 |
| DOC2B | MYF5 | 0.695024 | 3 | 0 | 3 |
| DOC2B | FBXL18 | 0.6935 | 4 | 0 | 4 |
| DOC2B | CDK20 | 0.690229 | 3 | 0 | 3 |
| DOC2B | DERL3 | 0.683574 | 4 | 0 | 4 |
| DOC2B | MYPOP | 0.68036 | 3 | 0 | 3 |
| DOC2B | FZR1 | 0.679277 | 5 | 0 | 5 |
| DOC2B | MPG | 0.676351 | 3 | 0 | 3 |
| DOC2B | C9orf16 | 0.67496 | 5 | 0 | 5 |
| DOC2B | SLC39A3 | 0.67259 | 3 | 0 | 3 |
For details and further investigation, click here
