| Full name: fibroblast growth factor 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12p13.32 | ||
| Entrez ID: 2251 | HGNC ID: HGNC:3684 | Ensembl Gene: ENSG00000111241 | OMIM ID: 134921 |
| Drug and gene relationship at DGIdb | |||
FGF6 involved pathways:
Expression of FGF6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FGF6 | 2251 | 208417_at | 0.0296 | 0.9389 | |
| GSE20347 | FGF6 | 2251 | 208417_at | -0.1286 | 0.0754 | |
| GSE23400 | FGF6 | 2251 | 208417_at | -0.2229 | 0.0000 | |
| GSE26886 | FGF6 | 2251 | 208417_at | -0.0491 | 0.7211 | |
| GSE29001 | FGF6 | 2251 | 208417_at | -0.1717 | 0.2023 | |
| GSE38129 | FGF6 | 2251 | 208417_at | -0.1987 | 0.0027 | |
| GSE45670 | FGF6 | 2251 | 208417_at | 0.0629 | 0.4436 | |
| GSE63941 | FGF6 | 2251 | 208417_at | 0.3515 | 0.0052 | |
| GSE77861 | FGF6 | 2251 | 208417_at | -0.1897 | 0.1019 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FGF6 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FGF6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FGF6 | 2251 | 6 | 4 | 20 | |
| GSE20123 | FGF6 | 2251 | 6 | 4 | 20 | |
| GSE43470 | FGF6 | 2251 | 10 | 3 | 30 | |
| GSE46452 | FGF6 | 2251 | 10 | 1 | 48 | |
| GSE47630 | FGF6 | 2251 | 12 | 2 | 26 | |
| GSE54993 | FGF6 | 2251 | 1 | 10 | 59 | |
| GSE54994 | FGF6 | 2251 | 10 | 2 | 41 | |
| GSE60625 | FGF6 | 2251 | 0 | 1 | 10 | |
| GSE74703 | FGF6 | 2251 | 9 | 2 | 25 | |
| GSE74704 | FGF6 | 2251 | 4 | 2 | 14 | |
| TCGA | FGF6 | 2251 | 40 | 6 | 50 |
Total number of gains: 108; Total number of losses: 37; Total Number of normals: 343.
Somatic mutations of FGF6:
Generating mutation plots.
Highly correlated genes for FGF6:
Showing top 20/1066 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FGF6 | CXCR6 | 0.75163 | 3 | 0 | 3 |
| FGF6 | TNFAIP8L2 | 0.751057 | 3 | 0 | 3 |
| FGF6 | GTSF1L | 0.711054 | 3 | 0 | 3 |
| FGF6 | TYR | 0.710371 | 5 | 0 | 5 |
| FGF6 | CD79A | 0.70957 | 3 | 0 | 3 |
| FGF6 | MUC5AC | 0.69316 | 5 | 0 | 5 |
| FGF6 | GALR3 | 0.692287 | 5 | 0 | 5 |
| FGF6 | MC5R | 0.691488 | 5 | 0 | 5 |
| FGF6 | CCDC7 | 0.690144 | 5 | 0 | 5 |
| FGF6 | LIPE | 0.685142 | 3 | 0 | 3 |
| FGF6 | LINC00474 | 0.684309 | 3 | 0 | 3 |
| FGF6 | PAX8 | 0.68154 | 6 | 0 | 5 |
| FGF6 | CD22 | 0.680589 | 4 | 0 | 4 |
| FGF6 | LEFTY1 | 0.679513 | 3 | 0 | 3 |
| FGF6 | ACSM5 | 0.677151 | 4 | 0 | 4 |
| FGF6 | FSTL4 | 0.674996 | 5 | 0 | 4 |
| FGF6 | ZMAT4 | 0.672164 | 3 | 0 | 3 |
| FGF6 | XCR1 | 0.671247 | 5 | 0 | 5 |
| FGF6 | IL9R | 0.670315 | 5 | 0 | 4 |
| FGF6 | SLC13A3 | 0.666962 | 4 | 0 | 4 |
For details and further investigation, click here
