| Full name: potassium voltage-gated channel subfamily A member 10 | Alias Symbol: Kv1.8 | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 3744 | HGNC ID: HGNC:6219 | Ensembl Gene: ENSG00000143105 | OMIM ID: 602420 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNA10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNA10 | 3744 | 208560_at | -0.0424 | 0.9011 | |
| GSE20347 | KCNA10 | 3744 | 208560_at | -0.0206 | 0.7980 | |
| GSE23400 | KCNA10 | 3744 | 208560_at | -0.1075 | 0.0019 | |
| GSE26886 | KCNA10 | 3744 | 208560_at | 0.1576 | 0.1934 | |
| GSE29001 | KCNA10 | 3744 | 208560_at | -0.1482 | 0.3165 | |
| GSE38129 | KCNA10 | 3744 | 208560_at | -0.1088 | 0.1108 | |
| GSE45670 | KCNA10 | 3744 | 208560_at | -0.0218 | 0.8417 | |
| GSE53622 | KCNA10 | 3744 | 54952 | -0.0569 | 0.7778 | |
| GSE53624 | KCNA10 | 3744 | 54952 | 0.1079 | 0.4563 | |
| GSE63941 | KCNA10 | 3744 | 208560_at | 0.0009 | 0.9961 | |
| GSE77861 | KCNA10 | 3744 | 208560_at | -0.0919 | 0.5404 | |
| GSE97050 | KCNA10 | 3744 | A_23_P126528 | -0.2883 | 0.2574 | |
| TCGA | KCNA10 | 3744 | RNAseq | -3.0968 | 0.0124 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KCNA10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNA10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNA10 | 3744 | 0 | 11 | 19 | |
| GSE20123 | KCNA10 | 3744 | 0 | 11 | 19 | |
| GSE43470 | KCNA10 | 3744 | 0 | 8 | 35 | |
| GSE46452 | KCNA10 | 3744 | 2 | 1 | 56 | |
| GSE47630 | KCNA10 | 3744 | 9 | 5 | 26 | |
| GSE54993 | KCNA10 | 3744 | 0 | 1 | 69 | |
| GSE54994 | KCNA10 | 3744 | 7 | 4 | 42 | |
| GSE60625 | KCNA10 | 3744 | 0 | 0 | 11 | |
| GSE74703 | KCNA10 | 3744 | 0 | 7 | 29 | |
| GSE74704 | KCNA10 | 3744 | 0 | 7 | 13 | |
| TCGA | KCNA10 | 3744 | 8 | 27 | 61 |
Total number of gains: 26; Total number of losses: 82; Total Number of normals: 380.
Somatic mutations of KCNA10:
Generating mutation plots.
Highly correlated genes for KCNA10:
Showing top 20/484 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNA10 | WFDC3 | 0.764095 | 3 | 0 | 3 |
| KCNA10 | IL9 | 0.714251 | 3 | 0 | 3 |
| KCNA10 | SERPIND1 | 0.713021 | 3 | 0 | 3 |
| KCNA10 | ADAM7 | 0.698106 | 3 | 0 | 3 |
| KCNA10 | NR0B2 | 0.696426 | 3 | 0 | 3 |
| KCNA10 | BCDIN3D-AS1 | 0.689558 | 3 | 0 | 3 |
| KCNA10 | OR12D3 | 0.673482 | 3 | 0 | 3 |
| KCNA10 | UMOD | 0.672751 | 4 | 0 | 4 |
| KCNA10 | CYP11B1 | 0.663262 | 3 | 0 | 3 |
| KCNA10 | GPR37L1 | 0.660971 | 4 | 0 | 4 |
| KCNA10 | SV2C | 0.658558 | 3 | 0 | 3 |
| KCNA10 | OR2W1 | 0.657404 | 3 | 0 | 3 |
| KCNA10 | LZTS1 | 0.654895 | 3 | 0 | 3 |
| KCNA10 | PRAMEF10 | 0.648105 | 4 | 0 | 3 |
| KCNA10 | PLA2G1B | 0.645495 | 3 | 0 | 3 |
| KCNA10 | ZP2 | 0.642101 | 3 | 0 | 3 |
| KCNA10 | GPA33 | 0.640689 | 3 | 0 | 3 |
| KCNA10 | CDKL5 | 0.636581 | 5 | 0 | 4 |
| KCNA10 | CCR9 | 0.634761 | 3 | 0 | 3 |
| KCNA10 | NTN1 | 0.633586 | 3 | 0 | 3 |
For details and further investigation, click here
