| Full name: zona pellucida glycoprotein 2 | Alias Symbol: ZPA | ||
| Type: protein-coding gene | Cytoband: 16p12.3-p12.2 | ||
| Entrez ID: 7783 | HGNC ID: HGNC:13188 | Ensembl Gene: ENSG00000103310 | OMIM ID: 182888 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZP2 | 7783 | 207933_at | 0.1553 | 0.4724 | |
| GSE20347 | ZP2 | 7783 | 207933_at | -0.0036 | 0.9617 | |
| GSE23400 | ZP2 | 7783 | 207933_at | -0.0831 | 0.0835 | |
| GSE26886 | ZP2 | 7783 | 207933_at | -0.0254 | 0.8451 | |
| GSE29001 | ZP2 | 7783 | 207933_at | 0.0424 | 0.8571 | |
| GSE38129 | ZP2 | 7783 | 207933_at | -0.1067 | 0.0779 | |
| GSE45670 | ZP2 | 7783 | 207933_at | 0.0400 | 0.6760 | |
| GSE53622 | ZP2 | 7783 | 35920 | 0.0821 | 0.5423 | |
| GSE53624 | ZP2 | 7783 | 35920 | 0.5345 | 0.0000 | |
| GSE63941 | ZP2 | 7783 | 207933_at | -0.0691 | 0.7223 | |
| GSE77861 | ZP2 | 7783 | 207933_at | -0.1924 | 0.2115 | |
| TCGA | ZP2 | 7783 | RNAseq | 0.0457 | 0.9882 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZP2 | 7783 | 6 | 3 | 21 | |
| GSE20123 | ZP2 | 7783 | 6 | 2 | 22 | |
| GSE43470 | ZP2 | 7783 | 3 | 3 | 37 | |
| GSE46452 | ZP2 | 7783 | 38 | 1 | 20 | |
| GSE47630 | ZP2 | 7783 | 11 | 6 | 23 | |
| GSE54993 | ZP2 | 7783 | 3 | 5 | 62 | |
| GSE54994 | ZP2 | 7783 | 3 | 10 | 40 | |
| GSE60625 | ZP2 | 7783 | 4 | 0 | 7 | |
| GSE74703 | ZP2 | 7783 | 3 | 2 | 31 | |
| GSE74704 | ZP2 | 7783 | 3 | 1 | 16 | |
| TCGA | ZP2 | 7783 | 19 | 13 | 64 |
Total number of gains: 99; Total number of losses: 46; Total Number of normals: 343.
Somatic mutations of ZP2:
Generating mutation plots.
Highly correlated genes for ZP2:
Showing top 20/346 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZP2 | AFP | 0.736538 | 3 | 0 | 3 |
| ZP2 | KLK14 | 0.718223 | 3 | 0 | 3 |
| ZP2 | HUNK | 0.714676 | 3 | 0 | 3 |
| ZP2 | SCN11A | 0.697711 | 3 | 0 | 3 |
| ZP2 | DGCR6L | 0.693552 | 4 | 0 | 3 |
| ZP2 | CCL1 | 0.692059 | 3 | 0 | 3 |
| ZP2 | DAB1 | 0.689033 | 3 | 0 | 3 |
| ZP2 | HCG9 | 0.680682 | 3 | 0 | 3 |
| ZP2 | ABCC6 | 0.678472 | 4 | 0 | 4 |
| ZP2 | MAG | 0.674742 | 3 | 0 | 3 |
| ZP2 | CLCNKB | 0.673363 | 3 | 0 | 3 |
| ZP2 | SEMA6B | 0.672119 | 3 | 0 | 3 |
| ZP2 | S100G | 0.666852 | 3 | 0 | 3 |
| ZP2 | ZIC4 | 0.666569 | 3 | 0 | 3 |
| ZP2 | SYN1 | 0.661782 | 3 | 0 | 3 |
| ZP2 | KIR2DS5 | 0.657869 | 3 | 0 | 3 |
| ZP2 | CITED1 | 0.654864 | 4 | 0 | 3 |
| ZP2 | HLA-DOA | 0.65273 | 4 | 0 | 3 |
| ZP2 | ITIH1 | 0.65224 | 4 | 0 | 3 |
| ZP2 | PCDH11X | 0.651219 | 3 | 0 | 3 |
For details and further investigation, click here
