| Full name: cyclin dependent kinase like 5 | Alias Symbol: EIEE2|CFAP247 | ||
| Type: protein-coding gene | Cytoband: Xp22.13 | ||
| Entrez ID: 6792 | HGNC ID: HGNC:11411 | Ensembl Gene: ENSG00000008086 | OMIM ID: 300203 |
| Drug and gene relationship at DGIdb | |||
Expression of CDKL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDKL5 | 6792 | 206575_at | -0.1194 | 0.6880 | |
| GSE20347 | CDKL5 | 6792 | 206575_at | -0.1058 | 0.1102 | |
| GSE23400 | CDKL5 | 6792 | 206575_at | -0.1408 | 0.0000 | |
| GSE26886 | CDKL5 | 6792 | 206575_at | -0.1294 | 0.3435 | |
| GSE29001 | CDKL5 | 6792 | 206575_at | -0.2482 | 0.0646 | |
| GSE38129 | CDKL5 | 6792 | 206575_at | -0.0811 | 0.3370 | |
| GSE45670 | CDKL5 | 6792 | 206575_at | -0.0205 | 0.8722 | |
| GSE53622 | CDKL5 | 6792 | 4122 | -0.7654 | 0.0000 | |
| GSE53624 | CDKL5 | 6792 | 4122 | -0.8277 | 0.0000 | |
| GSE63941 | CDKL5 | 6792 | 206575_at | -0.1680 | 0.2593 | |
| GSE77861 | CDKL5 | 6792 | 206575_at | -0.0698 | 0.5051 | |
| GSE97050 | CDKL5 | 6792 | A_24_P282343 | -0.4880 | 0.1984 | |
| SRP007169 | CDKL5 | 6792 | RNAseq | -2.1619 | 0.0000 | |
| SRP008496 | CDKL5 | 6792 | RNAseq | -2.3432 | 0.0000 | |
| SRP064894 | CDKL5 | 6792 | RNAseq | -1.2808 | 0.0000 | |
| SRP133303 | CDKL5 | 6792 | RNAseq | -0.4345 | 0.0321 | |
| SRP159526 | CDKL5 | 6792 | RNAseq | -1.0564 | 0.0037 | |
| SRP193095 | CDKL5 | 6792 | RNAseq | -1.6101 | 0.0000 | |
| SRP219564 | CDKL5 | 6792 | RNAseq | -1.1183 | 0.0401 | |
| TCGA | CDKL5 | 6792 | RNAseq | -0.4169 | 0.0161 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by CDKL5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDKL5:
No record found for this gene.
Somatic mutations of CDKL5:
Generating mutation plots.
Highly correlated genes for CDKL5:
Showing top 20/993 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDKL5 | FCHO2 | 0.723236 | 3 | 0 | 3 |
| CDKL5 | TMEM127 | 0.715772 | 4 | 0 | 4 |
| CDKL5 | ACSBG1 | 0.704407 | 4 | 0 | 4 |
| CDKL5 | IFNA10 | 0.703339 | 4 | 0 | 3 |
| CDKL5 | ZNF79 | 0.701767 | 3 | 0 | 3 |
| CDKL5 | NPBWR2 | 0.699181 | 3 | 0 | 3 |
| CDKL5 | TAB3 | 0.695805 | 3 | 0 | 3 |
| CDKL5 | LACTBL1 | 0.695489 | 3 | 0 | 3 |
| CDKL5 | GABRR2 | 0.689904 | 4 | 0 | 4 |
| CDKL5 | NPAP1 | 0.68893 | 5 | 0 | 5 |
| CDKL5 | ZNF614 | 0.687258 | 3 | 0 | 3 |
| CDKL5 | PSG9 | 0.686273 | 3 | 0 | 3 |
| CDKL5 | TMSB4Y | 0.68626 | 3 | 0 | 3 |
| CDKL5 | CTNNA1 | 0.685856 | 3 | 0 | 3 |
| CDKL5 | STRADB | 0.684912 | 3 | 0 | 3 |
| CDKL5 | PCSK5 | 0.682162 | 3 | 0 | 3 |
| CDKL5 | RAB4B | 0.681556 | 4 | 0 | 4 |
| CDKL5 | MPP5 | 0.68079 | 3 | 0 | 3 |
| CDKL5 | PYGO1 | 0.680075 | 5 | 0 | 5 |
| CDKL5 | MSH4 | 0.679876 | 4 | 0 | 4 |
For details and further investigation, click here
