| Full name: coiled-coil domain containing 157 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 550631 | HGNC ID: HGNC:33854 | Ensembl Gene: ENSG00000187860 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC157:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC157 | 550631 | 1568796_at | -0.1516 | 0.5883 | |
| GSE26886 | CCDC157 | 550631 | 1568796_at | -0.4602 | 0.0045 | |
| GSE45670 | CCDC157 | 550631 | 1568796_at | 0.0501 | 0.7461 | |
| GSE53622 | CCDC157 | 550631 | 90179 | 0.4276 | 0.0000 | |
| GSE53624 | CCDC157 | 550631 | 90179 | 0.2787 | 0.0048 | |
| GSE63941 | CCDC157 | 550631 | 1568796_at | -0.1680 | 0.3732 | |
| GSE77861 | CCDC157 | 550631 | 1568796_at | -0.3740 | 0.0006 | |
| GSE97050 | CCDC157 | 550631 | A_33_P3317103 | 0.0119 | 0.9640 | |
| SRP007169 | CCDC157 | 550631 | RNAseq | 0.4032 | 0.5023 | |
| SRP064894 | CCDC157 | 550631 | RNAseq | 0.3793 | 0.0850 | |
| SRP133303 | CCDC157 | 550631 | RNAseq | 0.1345 | 0.3986 | |
| SRP159526 | CCDC157 | 550631 | RNAseq | 0.5205 | 0.2649 | |
| SRP193095 | CCDC157 | 550631 | RNAseq | -0.0304 | 0.8259 | |
| SRP219564 | CCDC157 | 550631 | RNAseq | 0.2678 | 0.3828 | |
| TCGA | CCDC157 | 550631 | RNAseq | 0.0218 | 0.8802 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC157 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC157:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC157 | 550631 | 4 | 5 | 21 | |
| GSE20123 | CCDC157 | 550631 | 4 | 4 | 22 | |
| GSE43470 | CCDC157 | 550631 | 4 | 6 | 33 | |
| GSE46452 | CCDC157 | 550631 | 31 | 1 | 27 | |
| GSE47630 | CCDC157 | 550631 | 8 | 5 | 27 | |
| GSE54993 | CCDC157 | 550631 | 3 | 6 | 61 | |
| GSE54994 | CCDC157 | 550631 | 11 | 8 | 34 | |
| GSE60625 | CCDC157 | 550631 | 5 | 0 | 6 | |
| GSE74703 | CCDC157 | 550631 | 4 | 5 | 27 | |
| GSE74704 | CCDC157 | 550631 | 1 | 1 | 18 | |
| TCGA | CCDC157 | 550631 | 27 | 15 | 54 |
Total number of gains: 102; Total number of losses: 56; Total Number of normals: 330.
Somatic mutations of CCDC157:
Generating mutation plots.
Highly correlated genes for CCDC157:
Showing top 20/340 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC157 | SPINT3 | 0.798839 | 3 | 0 | 3 |
| CCDC157 | ODF4 | 0.756229 | 5 | 0 | 5 |
| CCDC157 | SH2D1B | 0.751488 | 3 | 0 | 3 |
| CCDC157 | ESAM | 0.737298 | 3 | 0 | 3 |
| CCDC157 | THPO | 0.73195 | 4 | 0 | 4 |
| CCDC157 | AP4B1 | 0.730885 | 3 | 0 | 3 |
| CCDC157 | GFRA2 | 0.724786 | 3 | 0 | 3 |
| CCDC157 | PAOX | 0.724334 | 3 | 0 | 3 |
| CCDC157 | PPOX | 0.719773 | 3 | 0 | 3 |
| CCDC157 | SLC5A10 | 0.719105 | 3 | 0 | 3 |
| CCDC157 | SNED1 | 0.718928 | 3 | 0 | 3 |
| CCDC157 | CYP4A11 | 0.71609 | 3 | 0 | 3 |
| CCDC157 | RGS12 | 0.71152 | 3 | 0 | 3 |
| CCDC157 | ABCC8 | 0.708939 | 3 | 0 | 3 |
| CCDC157 | MT3 | 0.708884 | 3 | 0 | 3 |
| CCDC157 | LRCH4 | 0.705788 | 3 | 0 | 3 |
| CCDC157 | OSM | 0.699394 | 3 | 0 | 3 |
| CCDC157 | TMEM105 | 0.69814 | 4 | 0 | 4 |
| CCDC157 | GPR78 | 0.691924 | 4 | 0 | 4 |
| CCDC157 | AKR7A3 | 0.691411 | 4 | 0 | 3 |
For details and further investigation, click here
