| Full name: solute carrier family 12 member 3 | Alias Symbol: NCCT | ||
| Type: protein-coding gene | Cytoband: 16q13 | ||
| Entrez ID: 6559 | HGNC ID: HGNC:10912 | Ensembl Gene: ENSG00000070915 | OMIM ID: 600968 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC12A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC12A3 | 6559 | 215274_at | 0.0505 | 0.8796 | |
| GSE20347 | SLC12A3 | 6559 | 208354_s_at | 0.0745 | 0.4131 | |
| GSE23400 | SLC12A3 | 6559 | 208354_s_at | -0.0937 | 0.0045 | |
| GSE26886 | SLC12A3 | 6559 | 215274_at | 0.0915 | 0.4431 | |
| GSE29001 | SLC12A3 | 6559 | 208354_s_at | -0.1062 | 0.5485 | |
| GSE38129 | SLC12A3 | 6559 | 208354_s_at | -0.0446 | 0.5511 | |
| GSE45670 | SLC12A3 | 6559 | 215274_at | 0.0744 | 0.4740 | |
| GSE53622 | SLC12A3 | 6559 | 16954 | 0.0020 | 0.9802 | |
| GSE53624 | SLC12A3 | 6559 | 16954 | 0.1780 | 0.0101 | |
| GSE63941 | SLC12A3 | 6559 | 215274_at | -0.0176 | 0.9238 | |
| GSE77861 | SLC12A3 | 6559 | 215274_at | -0.1261 | 0.3184 | |
| GSE97050 | SLC12A3 | 6559 | A_23_P77653 | 0.2073 | 0.2731 | |
| TCGA | SLC12A3 | 6559 | RNAseq | -1.4466 | 0.0895 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC12A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC12A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC12A3 | 6559 | 6 | 0 | 24 | |
| GSE20123 | SLC12A3 | 6559 | 6 | 1 | 23 | |
| GSE43470 | SLC12A3 | 6559 | 3 | 6 | 34 | |
| GSE46452 | SLC12A3 | 6559 | 38 | 1 | 20 | |
| GSE47630 | SLC12A3 | 6559 | 10 | 8 | 22 | |
| GSE54993 | SLC12A3 | 6559 | 2 | 4 | 64 | |
| GSE54994 | SLC12A3 | 6559 | 7 | 10 | 36 | |
| GSE60625 | SLC12A3 | 6559 | 4 | 0 | 7 | |
| GSE74703 | SLC12A3 | 6559 | 3 | 3 | 30 | |
| GSE74704 | SLC12A3 | 6559 | 4 | 0 | 16 | |
| TCGA | SLC12A3 | 6559 | 25 | 13 | 58 |
Total number of gains: 108; Total number of losses: 46; Total Number of normals: 334.
Somatic mutations of SLC12A3:
Generating mutation plots.
Highly correlated genes for SLC12A3:
Showing top 20/579 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC12A3 | LHFPL5 | 0.774312 | 3 | 0 | 3 |
| SLC12A3 | OR4D1 | 0.76237 | 3 | 0 | 3 |
| SLC12A3 | SHANK1 | 0.761703 | 3 | 0 | 3 |
| SLC12A3 | RAB3IL1 | 0.75998 | 4 | 0 | 4 |
| SLC12A3 | IGSF9B | 0.759964 | 3 | 0 | 3 |
| SLC12A3 | SLC22A25 | 0.748918 | 3 | 0 | 3 |
| SLC12A3 | GYPE | 0.737372 | 3 | 0 | 3 |
| SLC12A3 | SBNO2 | 0.734704 | 3 | 0 | 3 |
| SLC12A3 | MYBPH | 0.734696 | 4 | 0 | 3 |
| SLC12A3 | SHISA7 | 0.731328 | 3 | 0 | 3 |
| SLC12A3 | SCGN | 0.729888 | 5 | 0 | 5 |
| SLC12A3 | C1QTNF1 | 0.729696 | 3 | 0 | 3 |
| SLC12A3 | ZNF236 | 0.72622 | 3 | 0 | 3 |
| SLC12A3 | TEX22 | 0.718563 | 3 | 0 | 3 |
| SLC12A3 | KCNA6 | 0.716001 | 3 | 0 | 3 |
| SLC12A3 | TSSK3 | 0.715989 | 3 | 0 | 3 |
| SLC12A3 | HHIP | 0.714383 | 3 | 0 | 3 |
| SLC12A3 | RHAG | 0.710192 | 3 | 0 | 3 |
| SLC12A3 | ISLR2 | 0.705497 | 4 | 0 | 3 |
| SLC12A3 | STAC3 | 0.701937 | 3 | 0 | 3 |
For details and further investigation, click here
