| Full name: potassium voltage-gated channel modifier subfamily S member 1 | Alias Symbol: Kv9.1 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 3787 | HGNC ID: HGNC:6300 | Ensembl Gene: ENSG00000124134 | OMIM ID: 602905 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNS1 | 3787 | 207366_at | 0.2915 | 0.5482 | |
| GSE20347 | KCNS1 | 3787 | 207366_at | 0.1725 | 0.0870 | |
| GSE23400 | KCNS1 | 3787 | 207366_at | 0.0109 | 0.8105 | |
| GSE26886 | KCNS1 | 3787 | 207366_at | 0.5161 | 0.0090 | |
| GSE29001 | KCNS1 | 3787 | 207366_at | -0.1601 | 0.3336 | |
| GSE38129 | KCNS1 | 3787 | 207366_at | -0.0054 | 0.9784 | |
| GSE45670 | KCNS1 | 3787 | 207366_at | 0.1667 | 0.1323 | |
| GSE53622 | KCNS1 | 3787 | 62337 | 0.8927 | 0.0000 | |
| GSE53624 | KCNS1 | 3787 | 62337 | 0.9035 | 0.0000 | |
| GSE63941 | KCNS1 | 3787 | 207366_at | 0.4117 | 0.1179 | |
| GSE77861 | KCNS1 | 3787 | 207366_at | 0.1177 | 0.5531 | |
| GSE97050 | KCNS1 | 3787 | A_23_P321846 | 0.2890 | 0.6431 | |
| SRP064894 | KCNS1 | 3787 | RNAseq | 0.6791 | 0.0119 | |
| SRP133303 | KCNS1 | 3787 | RNAseq | 0.1653 | 0.5909 | |
| SRP159526 | KCNS1 | 3787 | RNAseq | 0.9847 | 0.0708 | |
| TCGA | KCNS1 | 3787 | RNAseq | 2.0690 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KCNS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KCNS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNS1 | 3787 | 13 | 1 | 16 | |
| GSE20123 | KCNS1 | 3787 | 13 | 1 | 16 | |
| GSE43470 | KCNS1 | 3787 | 12 | 1 | 30 | |
| GSE46452 | KCNS1 | 3787 | 29 | 0 | 30 | |
| GSE47630 | KCNS1 | 3787 | 24 | 1 | 15 | |
| GSE54993 | KCNS1 | 3787 | 0 | 17 | 53 | |
| GSE54994 | KCNS1 | 3787 | 25 | 0 | 28 | |
| GSE60625 | KCNS1 | 3787 | 0 | 0 | 11 | |
| GSE74703 | KCNS1 | 3787 | 10 | 1 | 25 | |
| GSE74704 | KCNS1 | 3787 | 9 | 0 | 11 | |
| TCGA | KCNS1 | 3787 | 45 | 3 | 48 |
Total number of gains: 180; Total number of losses: 25; Total Number of normals: 283.
Somatic mutations of KCNS1:
Generating mutation plots.
Highly correlated genes for KCNS1:
Showing top 20/589 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNS1 | BLK | 0.786865 | 3 | 0 | 3 |
| KCNS1 | CACNA1S | 0.743467 | 3 | 0 | 3 |
| KCNS1 | SERPINA6 | 0.733903 | 3 | 0 | 3 |
| KCNS1 | OR1A1 | 0.733767 | 5 | 0 | 5 |
| KCNS1 | ZNF771 | 0.722061 | 4 | 0 | 4 |
| KCNS1 | TCL6 | 0.702494 | 4 | 0 | 3 |
| KCNS1 | CHGA | 0.694726 | 3 | 0 | 3 |
| KCNS1 | S1PR4 | 0.692564 | 5 | 0 | 4 |
| KCNS1 | STAT2 | 0.68935 | 4 | 0 | 4 |
| KCNS1 | PRR34 | 0.687386 | 4 | 0 | 4 |
| KCNS1 | MAPRE3 | 0.68311 | 4 | 0 | 4 |
| KCNS1 | OR10H3 | 0.683079 | 5 | 0 | 5 |
| KCNS1 | UGT2B28 | 0.67512 | 4 | 0 | 3 |
| KCNS1 | CATIP-AS1 | 0.67327 | 3 | 0 | 3 |
| KCNS1 | DNASE1L2 | 0.672159 | 5 | 0 | 4 |
| KCNS1 | C8A | 0.672042 | 4 | 0 | 3 |
| KCNS1 | CHST4 | 0.670737 | 4 | 0 | 4 |
| KCNS1 | RNASEH2B | 0.667211 | 4 | 0 | 4 |
| KCNS1 | FAM217A | 0.664612 | 3 | 0 | 3 |
| KCNS1 | C10orf95 | 0.663292 | 5 | 0 | 4 |
For details and further investigation, click here
