| Full name: family with sequence similarity 217 member A | Alias Symbol: MGC43581 | ||
| Type: protein-coding gene | Cytoband: 6p25.2 | ||
| Entrez ID: 222826 | HGNC ID: HGNC:21362 | Ensembl Gene: ENSG00000145975 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FAM217A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM217A | 222826 | 237619_at | 0.1408 | 0.5431 | |
| GSE26886 | FAM217A | 222826 | 237619_at | 0.0997 | 0.2517 | |
| GSE45670 | FAM217A | 222826 | 237619_at | -0.0024 | 0.9819 | |
| GSE53622 | FAM217A | 222826 | 92191 | 0.0806 | 0.5571 | |
| GSE53624 | FAM217A | 222826 | 92191 | -0.0496 | 0.5991 | |
| GSE63941 | FAM217A | 222826 | 237619_at | 0.0696 | 0.6572 | |
| GSE77861 | FAM217A | 222826 | 237619_at | 0.0366 | 0.7317 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM217A expression:
Note: Click image to view full size file.
Copy number change of FAM217A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM217A | 222826 | 4 | 5 | 21 | |
| GSE20123 | FAM217A | 222826 | 4 | 5 | 21 | |
| GSE43470 | FAM217A | 222826 | 8 | 2 | 33 | |
| GSE46452 | FAM217A | 222826 | 1 | 10 | 48 | |
| GSE47630 | FAM217A | 222826 | 7 | 8 | 25 | |
| GSE54993 | FAM217A | 222826 | 1 | 1 | 68 | |
| GSE54994 | FAM217A | 222826 | 10 | 3 | 40 | |
| GSE60625 | FAM217A | 222826 | 0 | 1 | 10 | |
| GSE74703 | FAM217A | 222826 | 7 | 2 | 27 | |
| GSE74704 | FAM217A | 222826 | 2 | 2 | 16 | |
| TCGA | FAM217A | 222826 | 16 | 29 | 51 |
Total number of gains: 60; Total number of losses: 68; Total Number of normals: 360.
Somatic mutations of FAM217A:
Generating mutation plots.
Highly correlated genes for FAM217A:
Showing top 20/41 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM217A | P4HA3 | 0.686894 | 3 | 0 | 3 |
| FAM217A | ZFP92 | 0.681823 | 3 | 0 | 3 |
| FAM217A | KCNS1 | 0.664612 | 3 | 0 | 3 |
| FAM217A | GLP1R | 0.664068 | 3 | 0 | 3 |
| FAM217A | GPR21 | 0.657746 | 3 | 0 | 3 |
| FAM217A | TCTE3 | 0.638206 | 3 | 0 | 3 |
| FAM217A | CRYGA | 0.623316 | 3 | 0 | 3 |
| FAM217A | CNGB3 | 0.621858 | 4 | 0 | 3 |
| FAM217A | CD101 | 0.615873 | 4 | 0 | 4 |
| FAM217A | SERPINA9 | 0.615249 | 3 | 0 | 3 |
| FAM217A | GNAO1 | 0.610504 | 4 | 0 | 3 |
| FAM217A | LINC00928 | 0.605172 | 4 | 0 | 3 |
| FAM217A | KDM6B | 0.596568 | 3 | 0 | 3 |
| FAM217A | BTG4 | 0.591452 | 3 | 0 | 3 |
| FAM217A | GAMT | 0.590697 | 3 | 0 | 3 |
| FAM217A | PRKAR1B | 0.585144 | 3 | 0 | 3 |
| FAM217A | LINC00520 | 0.58242 | 4 | 0 | 3 |
| FAM217A | SLC8A3 | 0.582211 | 4 | 0 | 3 |
| FAM217A | ROPN1L | 0.581906 | 3 | 0 | 3 |
| FAM217A | FAM219A | 0.580338 | 3 | 0 | 3 |
For details and further investigation, click here

