| Full name: FAST kinase domains 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q33.3 | ||
| Entrez ID: 22868 | HGNC ID: HGNC:29160 | Ensembl Gene: ENSG00000118246 | OMIM ID: 612322 |
| Drug and gene relationship at DGIdb | |||
Expression of FASTKD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FASTKD2 | 22868 | 216996_s_at | -0.0486 | 0.9543 | |
| GSE20347 | FASTKD2 | 22868 | 216996_s_at | 0.2412 | 0.2862 | |
| GSE23400 | FASTKD2 | 22868 | 216996_s_at | 0.2638 | 0.0001 | |
| GSE26886 | FASTKD2 | 22868 | 216996_s_at | -0.1689 | 0.5523 | |
| GSE29001 | FASTKD2 | 22868 | 216996_s_at | 0.2473 | 0.5220 | |
| GSE38129 | FASTKD2 | 22868 | 216996_s_at | 0.3483 | 0.0177 | |
| GSE45670 | FASTKD2 | 22868 | 216996_s_at | 0.2048 | 0.1341 | |
| GSE53622 | FASTKD2 | 22868 | 107575 | -0.1060 | 0.0862 | |
| GSE53624 | FASTKD2 | 22868 | 107575 | 0.0446 | 0.5636 | |
| GSE63941 | FASTKD2 | 22868 | 216996_s_at | 0.3182 | 0.2814 | |
| GSE77861 | FASTKD2 | 22868 | 216996_s_at | 0.3505 | 0.1462 | |
| GSE97050 | FASTKD2 | 22868 | A_23_P345830 | -0.1108 | 0.7013 | |
| SRP007169 | FASTKD2 | 22868 | RNAseq | 0.0368 | 0.9266 | |
| SRP008496 | FASTKD2 | 22868 | RNAseq | -0.0713 | 0.7512 | |
| SRP064894 | FASTKD2 | 22868 | RNAseq | -0.2422 | 0.0417 | |
| SRP133303 | FASTKD2 | 22868 | RNAseq | 0.1295 | 0.2426 | |
| SRP159526 | FASTKD2 | 22868 | RNAseq | -0.1811 | 0.4094 | |
| SRP193095 | FASTKD2 | 22868 | RNAseq | -0.1433 | 0.2223 | |
| SRP219564 | FASTKD2 | 22868 | RNAseq | -0.2308 | 0.2734 | |
| TCGA | FASTKD2 | 22868 | RNAseq | -0.0714 | 0.1276 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FASTKD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FASTKD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FASTKD2 | 22868 | 3 | 6 | 21 | |
| GSE20123 | FASTKD2 | 22868 | 3 | 6 | 21 | |
| GSE43470 | FASTKD2 | 22868 | 2 | 4 | 37 | |
| GSE46452 | FASTKD2 | 22868 | 1 | 4 | 54 | |
| GSE47630 | FASTKD2 | 22868 | 4 | 5 | 31 | |
| GSE54993 | FASTKD2 | 22868 | 0 | 3 | 67 | |
| GSE54994 | FASTKD2 | 22868 | 8 | 9 | 36 | |
| GSE60625 | FASTKD2 | 22868 | 0 | 3 | 8 | |
| GSE74703 | FASTKD2 | 22868 | 2 | 3 | 31 | |
| GSE74704 | FASTKD2 | 22868 | 2 | 2 | 16 | |
| TCGA | FASTKD2 | 22868 | 14 | 22 | 60 |
Total number of gains: 39; Total number of losses: 67; Total Number of normals: 382.
Somatic mutations of FASTKD2:
Generating mutation plots.
Highly correlated genes for FASTKD2:
Showing top 20/757 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FASTKD2 | KCTD18 | 0.800872 | 3 | 0 | 3 |
| FASTKD2 | CIB1 | 0.791727 | 3 | 0 | 3 |
| FASTKD2 | STX4 | 0.781489 | 3 | 0 | 3 |
| FASTKD2 | FOPNL | 0.779402 | 3 | 0 | 3 |
| FASTKD2 | PPIL3 | 0.779118 | 3 | 0 | 3 |
| FASTKD2 | NDUFA9 | 0.770703 | 4 | 0 | 4 |
| FASTKD2 | ALDOA | 0.752502 | 3 | 0 | 3 |
| FASTKD2 | HEATR5A | 0.748371 | 3 | 0 | 3 |
| FASTKD2 | NBAS | 0.747809 | 3 | 0 | 3 |
| FASTKD2 | FBXO30 | 0.746312 | 3 | 0 | 3 |
| FASTKD2 | METAP2 | 0.743955 | 6 | 0 | 5 |
| FASTKD2 | ARPC5 | 0.74267 | 3 | 0 | 3 |
| FASTKD2 | TRAPPC6B | 0.736668 | 3 | 0 | 3 |
| FASTKD2 | MAP4K5 | 0.729132 | 3 | 0 | 3 |
| FASTKD2 | ADAM9 | 0.725204 | 3 | 0 | 3 |
| FASTKD2 | SGMS1 | 0.72458 | 4 | 0 | 3 |
| FASTKD2 | PHLPP1 | 0.724532 | 3 | 0 | 3 |
| FASTKD2 | CTDSPL2 | 0.723775 | 3 | 0 | 3 |
| FASTKD2 | ATP6V0B | 0.719229 | 4 | 0 | 4 |
| FASTKD2 | EIF3E | 0.709026 | 3 | 0 | 3 |
For details and further investigation, click here
